Lefty (LEFTY1) (NM_020997) Human Untagged Clone

CAT#: SC122900

LEFTY1 (untagged)-Human left-right determination factor 1 (LEFTY1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LEFTY1
• Synonyms: LEFTB; LEFTYB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020997 edited
  TGAGACCCTCCTGCAGCCTTCTCAAGGGACAGCCCCACTCTGCCTCTTGCTCCTCCAGGG
  CAGCACCATGCAGCCCCTGTGGCTCTGCTGGGCACTCTGGGTGTTGCCCCTGGCCAGCCC
  CGGGGCCGCCCTGACCGGGGAGCAGCTCCTGGGCAGCCTGCTGCGGCAGCTGCAGCTCAA
  AGAGGTGCCCACCCTGGACAGGGCCGACATGGAGGAGCTGGTCATCCCCACCCACGTGAG
  GGCCCAGTACGTGGCCCTGCTGCAGCGCAGCCACGGGGACCGCTCCCGCGGAAAGAGGTT
  CAGCCAGAGCTTCCGAGAGGTGGCCGGCAGGTTCCTGGCGTTGGAGGCCAGCACACACCT
  GCTGGTGTTCGGCATGGAGCAGCGGCTGCCGCCCAACAGCGAGCTGGTGCAGGCCGTGCT
  GCGGCTCTTCCAGGAGCCGGTCCCCAAGGCCGCGCTGCACAGGCACGGGCGGCTGTCCCC
  GCGCAGCGCCCGGGCCCGGGTGACCGTCGAGTGGCTGCGCGTCCGCGACGACGGCTCCAA
  CCGCACCTCCCTCATCGACTCCAGGCTGGTGTCCGTCCACGAGAGCGGCTGGAAGGCCTT
  CGACGTGACCGAGGCCGTGAACTTCTGGCAGCAGCTGAGCCGGCCCCGGCAGCCGCTGCT
  GCTACAGGTGTCGGTGCAGAGGGAGCATCTGGGCCCGCTGGCGTCCGGCGCCCACAAGCT
  GGTCCGCTTTGCCTCGCAGGGGGCGCCAGCCGGGCTTGGGGAGCCCCAGCTGGAGCTGCA
  CACCCTGGACCTTGGGGACTATGGAGCTCAGGGCGACTGTGACCCTGAAGCACCAATGAC
  CGAGGGCACCCGCTGCTGCCGCCAGGAGATGTACATTGACCTGCAGGGGATGAAGTGGGC
  CGAGAACTGGGTGCTGGAGCCCCCGGGCTTCCTGGCTTATGAGTGTGTGGGCACCTGCCG
  GCAGCCCCCGGAGGCCCTGGCCTTCAAGTGGCCGTTTCTGGGGCCTCGACAGTGCATCGC
  CTCGGAGACTGACTCGCTGCCCATGATCGTCAGCATCAAGGAGGGAGGCAGGACCAGGCC
  CCAGGTGGTCAGCCTGCCCAACATGAGGGTGCAGAAGTGCAGCTGTGCCTCGGATGGTGC
  GCTCGTGCCAAGGAGGCTCCAGCCATAGGCGCCTAGTGTAGCCATCGAGGGACTTGACTT
  GTGTGTGTTTCTGAAGTGTTCGAGGGTACCAGGAGAGCTGGCGATGACTGAACTGCTGAT
  GGACAAATGCTCTGTGCTCTCTAGTGAGCCCTGAATTTGCTTCCTCTGACAAGTTACCTC
  ACCTAATTTTTGCTTCTCAGGAATGAGAATCTTTGGCCACTGGAGAGCCCTTGCTCAGTT
  TTCTCTATTCTTATTATTCACTGCACTATATTCTAAGCACTTACATGTGGAGATACTGTA
  ACTTGAGGGCAGAAAGCCCAATGTGTCATTGTTTACTTGTCCTGTCACTGGATCTGGGCT
  AAAGTCCTCCACCACCACTCTGGACCTAAGACCTGGGGTTAAGTGTGGGTTGTGCATCCC
  CAATCCAGATAATAAAGACTTTGTAAAACATGAATAAAACACATTTTATTCTAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020997 unedited
  NNAAGTTCGAATTTGTATACGACTCATATAGGCGGCCGCGNATTCCCGGGATTGAGACCC
  TCCTGCAGCCTTCTCAAGGACAGCCCCACTCTGCCTCTTGCTCCTCCAGGGCAGCACCAT
  GCAGCCCCTGTGGCTCTGCTGGGCACTCTGGGTGTTGCCCCTGGCCAGCCCCGGGGCCGC
  CCTGACCGGGGAGCAGCTCCTGGGCAGCCTGCTGCGGCAGCTGCAGCTCAAAGAGGTGCC
  CACCCTGGACAGGGCCGACATGGAGGAGCTGGTCATCCCCACCCACGTGAGGGCCCAGTA
  CGTGGCCCTGCTGCAGCGCAGCCACGGGGACCGCTCCCGCGGAAAGAGGTTCAGCCAGAG
  CTTCCGAGAGGTGGCCGGCAGGTTCCTGGCGTTGGAGGCCAGCACACACCTGCTGGTGTT
  CGGCATGGAGCAGCGGCTGCCGCCCAACAGCGAGCTGGTGCAGGCCGTGCTGCGGCTCTT
  CCAGGAGCCGGTCCCCAAGGCCGCGCTGCACAGGCACGGGCGGCTGTCCCCGCGCAGCGC
  CCGGGCCCGGGTGACCGTCGAGTGGCTGCGCGTCCGCGACGACGGCTCCAACCGCACCTC
  CCTCATCGACTCCAGGCTGGTGTCCGTCCACGAGAGCGGCTGGAAGGCCTTCGACGTGAC
  CGAGGCCGTGAACTTCTGGCAGCAGCTGAGCCGGCCCCGGCAGCCGCTGCTGCTACAGGT
  GTCGGTGCAGAGGGAGCATCTGGGCCCGCTGGCGTCCGGCGCCCACAAGCTGGTCCGCTT
  TGCCTCGCAGGGGCGCCAGCCGGGCTTTGGGAGCCCCAGCTGGAGCTGCACACCCTGGAC
  CTTGGGGACTATGGAGCTCANGGCGACTGTGACCCTGAAGCACCATGACCGAGGGCACCG
  C
  
• Restriction Sites: Please inquire
• ACCN: NM_020997
• ORF Size: 1101 bp
• Insert Size: 1644
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020997.2, NP_066277.1
• RefSeq Size: 1647
• RefSeq ORF: 1101
• Locus ID: 10637
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: TGF-beta signaling pathway
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016]