RGR (BC008094) Human Untagged Clone

CAT#: SC123730

RGR (untagged)-Homo sapiens, Similar to retinal G protein coupled receptor, clone MGC:17108 IMAGE:4179231, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGR
• Synonyms: RP44
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC008094 edited
  TGAGGATGGCAGAGACCAGTGCCTTGCCCACCGGCTTCGGGGAGCTCGAGGTGCTGGCTG
  TGGGGATGGTGCTACTGGTGGAAGACCCCGGAGCTGCGGACTCCCTGCCACCTACTGGTG
  CTGAGCTTGGCTCTTGCGGACAGTGGGATCAGCCTGAATGCCCTCGTTGCAGCCACATCC
  AGCCTTCTCCGTGTCTCCCACAGGCGCTGGCCCTACGGCTCGGACGGCTGCCAGGCTCAC
  GGCTTCCAGGGCTTTGTGACAGCGTTGGCCAGCATCTGCAGCAGTGCAGCCATCGCATGG
  GGGCGTTATCACCACTACTGCACCCGCCAAAATGCTGCCATCGGTCTCATCATTTTGAGT
  GGCGATAGGTTAGCCCTCTTGTCCACTTGGCCTCAGAGCACTTCTCCCACTCCTTACATC
  CCAGCCCCTGCCCCTAATGCTCCCTTGGACCATCTTATACACACACACACACACACACAC
  ACACACACACACACACACACACACCACCTTCTCAGATAGCAACAGGCTTCTCTGCCTCAA
  TATAGAACAGTTAATCCCTGTGCCAGAGGCCTTAGATCAAAGCCCTTTCTATACTGAGAG
  CATGGCAGAGCAGTGTGAAGGCAGGCAAAGGGGAATGAGGAGGTCTGAATTCATCTACTC
  CATCCCTGGGTGGTTGTAGGCATGTCACCTTGGCCATCTGTTTCTAAAGCTGAAAGTCTG
  AGGCAGCACAATGGTCCAGGTAGATATTAATTATTGTGCCCACAGAGAATTGTTTGAACC
  TGGAAGGCAGAGGTTGCAGTGAGCTGAGATGGCACCACTGCACTCCAGCCTGGGCAACAG
  AATGAGACTCCGCCTCAATAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC008094 unedited
  NAGGTCGCATATTGTATACGACTCACTATAGGCGGCCGCGNATTCATATCTGGTACCGGT
  CCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCCCACGCGTCCGTGAGGATGGCAG
  AGACCAGTGCCTTGCCCACCGGCTTCGGGGAGCTCGAGGTGCTGGCTGTGGGGATGGTGC
  TACTGGTGGAAGACCCCGGAGCTGCGGACTCCCTGCCACCTACTGGTGCTGAGCTTGGCT
  CTTGCGGACAGTGGGATCAGCCTGAATGCCCTCGTTGCAGCCACATCCAGCCTTCTCCGT
  GTCTCCCACAGGCGCTGGCCCTACGGCTCGGACGGCTGCCAGGCTCACGGCTTCCAGGGC
  TTTGTGACAGCGTTGGCCAGCATCTGCAGCAGTGCAGCCATCGCATGGGGGCGTTATCAC
  CACTACTGCACCCGCCAAAATGCTGCCATCGGTCTCATCATTTTGAGTGGCGATAGGTTA
  GCCCTCTTGTCCACTTGGCCTCAGAGCACTTCTCCCACTCCTTACATCCCAGCCCCTGCC
  CCTAATGCTCCCTTGGACCATCTTATACACACACACACACACACACACACACACACACAC
  ACACACACACACCACCTTCTCAGATAGCAACAGGCTTCTCTGCCTCAATATAGAACAGTT
  AATCCCTGTGCCAGAGGCCTTATATCAAAGCCCTTTCTATACTGAGAGCATGGCAGAGCA
  GTGTGAAGGCAGGCAAAGGGGAATGAGGAGGTCTGAATTCATCTACTCCATCCCTGGGTG
  GTTGTAGGCATGTCACCTTGGCCATCTGTTTCTAAAGCTGAAAGTCTGANGCAGCACAAT
  GGTCCAGGTAGATATTAATATTGTGCCCACAGGACAATGTTTGATCCTGGAAGCCAAAGT
  TGGCATGAGCTGAAATGGCACACTGCACTCATCCTGGGCACAGATGAGACTCCGCT
  
• Restriction Sites: Please inquire
• ACCN: BC008094
• Insert Size: 877 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC008094.1, AAH08094.1
• RefSeq Size: 877 bp
• RefSeq ORF: 363 bp
• Locus ID: 5995
• Cytogenetics: 10q23.1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: 'This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'