BHMT2 (NM_017614) Human Untagged Clone

CAT#: SC124281

BHMT2 (untagged)-Human betaine--homocysteine S-methyltransferase 2 (BHMT2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BHMT2
• Synonyms: FLJ20001
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017614, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCACCTGCTGGACGCCCGGGGGCCAAGAAGGGGATTTTGGAGCGCCTGGAGAGTGGGGAGGTTGTGA
  TTGGAGATGGCAGCTTTCTCATTACTCTGGAGAAGAGAGGCTATGTGAAGGCTGGGCTCTGGACTCCAGA
  GGCAGTGATAGAACACCCAGACGCAGTTCGTCAACTTCACATGGAATTCTTGAGAGCAGGATCAAATGTC
  ATGCAGACTTTTACCTTTTCTGCCAGTGAGGACAATATGGAAAGCAAGTGGGAAGATGTAAATGCTGCTG
  CCTGTGACCTCGCCAGGGAAGTGGCTGGCAAAGGTGATGCTTTGGTAGCAGGGGGGATCTGCCAGACATC
  AATATACAAATACCAGAAGGATGAAGCTAGAATTAAAAAACTTTTTCGACAACAGCTAGAAGTTTTTGCC
  TGGAAAAATGTGGACTTCTTGATTGCAGAGTATTTTGAGCACGTTGAAGAAGCTGTGTGGGCTGTGGAAG
  TCTTAAAAGAATCAGATAGACCCGTGGCAGTTACCATGTGCATAGGCCCAGAGGGAGACATGCATGATAT
  AACCCCCGGAGAATGTGCTGTGAGGCTGGTGAAGGCAGGGGCTTCCATCGTTGGCGTGAACTGCCGCTTT
  GGGCCCGACACCAGCTTGAAGACGATGGAGCTCATGAAGGAGGGTCTTGAGTGGGCAGGGCTGAAAGCGC
  ACCTCATGGTGCAGCCTCTGGGGTTCCACGCGCCTGACTGTGGCAAAGAGGGGTTTGTGGATCTCCCAGA
  ATATCCCTTTGGACTGGAGTCCAGAGTTGCCACCAGATGGGATATTCAAAAATACGCCAGAGAGGCCTAC
  AACCTGGGGGTCAGGTACATTGGCGGGTGCTGTGGATTTGAGCCCTACCACATCAGGGCAATTGCAGAGG
  AGCTGGCCCCAGAAAGGGGCTTTTTGCCACCAGCTTCAGAAAAACACGGCAGCTGGGGAAGTGGTTTGGA
  CATGCACACCAAACCCTGGATTAGAGCAAGGGCTCGAAGGGAGTATTGGGAGAATCTGCTGCCAGCTTCA
  GGCAGACCTTTCTGTCCTTCGCTGTCAAAGCCAGACTTCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017614 unedited
  NNGGTTCACATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGGAACCC
  GGCGCCCACAGAGCCGCGGCACCATGGCACCTGCTGGACGCCCGGGGGCCAAGAAGGGGA
  TTTTGGAGCGCCTGGAGAGTGGGGAGGTTGTGATTGGAGATGGCAGCTTTCTCATTACTC
  TGGAGAAGAGAGGCTATGTGAAGGCTGGGCTCTGGACTCCAGAGGCAGTGATAGAACACC
  CAGACGCAGTTCGTCAACTTCACATGGAATTCTTGAGAGCAGGATCAAATGTCATGCAGA
  CTTTTACCTTTTCTGCCAGTGAGGACAATATGGAAAGCAAGTGGGAAGATGTAAATGCTG
  CTGCCTGTGACCTCGCCAGGGAAGTGGCTGGCAAAGGTGATGCTTTGGTAGCAGGGGGGA
  TCTGCCAGACATCAATATACAAATACCAGAAGGATGAAGCTAGAATTAAAAAACTTTTTC
  GACAACAGCTAGAAGTTTTTGCCTGGAAAAATGTGGACTTCTTGATTGCAGAGTATTTTG
  AGCACGTTGAAGAAGCTGTGTGGGCTGTGGAAGTCTTAAAAGAATCAGATAGACCCGTGG
  CAGTTACCATGTGCATAGGCCCAGAGGGAGACATGCATGATATAACCCCCGGAGAATGTG
  CTGTGAGGCTGGTGAAGGCAGGGGCTTCCATCGTTGGCGTGAACTGCCGCTTTGGGCCCG
  ACACCAGCTTGAAGACGATGGAGCTCATGAAGGANGGTCTTGAGTGGGCAGGGCTGAAAG
  CGCACCTCATGGTGCAGCCTCTGGGGTTCCACGCGCCTGACTGTGGCANAGAGGGGGTTT
  TGTGGATCTCCCAGATATCCCTTTGGACTGGAGTCCAGAGTTGCCACCAGATGGGATATT
  CAAAAATACGCCCAGAGAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017614
• ORF Size: 1092 bp
• Insert Size: 2750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017614.3, NP_060084.2
• RefSeq Size: 2007
• RefSeq ORF: 1092
• Locus ID: 23743
• Domains: S-methyl_trans
• Gene Summary: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.