XRCC4 (BC005259) Human Untagged Clone

CAT#: SC126431

XRCC4 (untagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 4, mRNA (cDNA clone MGC:12297 IMAGE:3838919), complete cds


Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol XRCC4
Synonyms DNA repair protein XRCC4; X-ray repair, complementing defective, repair in Chinese hamster; X-ray repair complementing defective repair in Chinese hamster cells 4; X-ray repair cross complementing protein 4
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for BC005259 edited
AAACCTTGATCTGTGAAAGCGGGCGTTTTGGAAGATACCGGAAGTAGAGTCACGGAGAGG
TATTAAGAAATGGAGAGAAAAATAAGCAGAATCCACCTTGTTTCTGAACCCAGTATAACT
CATTTTCTACAAGTATCTTGGGAGAAAACACTGGAATCTGGTTTTGTTATTACACTTACT
GATGGTCATTCAGCATGGACTGGGACAGTTTCTGAATCAGAGATTTCCCAAGAAGCTGAT
GACATGGCAATGGAAAAAGGGAAATATGTTGGTGAACTGAGAAAAGCATTGTTGTCAGGA
GCAGGACCAGCTGATGTATACACGTTTAATTTTTCTAAAGAGTCTTGTTATTTCTTCTTT
GAGAAAAACCTGAAAGATGTCTCATTCAGACTTGGTTCCTTCAACCTAGAGAAAGTTGAA
AACCCAGCTGAAGTCATTAGAGAACTTATTTGTTATTGCTTGGACACCATTGCAGAAAAT
CAAGCCAAAAATGAGCACCTGCAGAAAGAAAATGAAAGGCTTCTGAGAGATTGGAATGAT
GTTCAAGGACGATTTGAAAAATGTGTGAGTGCTAAGGAAGCTTTGGAGACTGATCTTTAT
AAGCGGTTTATTCTGGTGTTGAATGAGAAGAAAACAAAAATCAGAAGTTTGCATAATAAA
TTATTAAATGCAGCTCAAGAACGAGAAAAGGACATCAAACAAGAAGGGGAAACTGCAATC
TGTTCTGAAATGACTGCTGACCGAGATCCAGTCTATGATGAGAGTACTGATGAGGAAAGT
GAAAACCAAACTGATCTCTCTGGGTTGGCTTCAGCTGCTGTAAGTAAAGATGATTCCATT
ATTTCAAGTCTTGATGTCACTGATATTGCACCAAGTAGAAAAAGGAGACAGCGAATGCAA
AGAAATCTTGGGACAGAACCTAAAATGGCTCCTCAGGAGAATCAGCTTCAAGAAAAGGAA
AAAGGGAGGAAGAAGGAGACTTCAGAGAAAGAGGCCGTGTGATGGAAGCAAAATCAGAGA
GAAAAGATGCTAAGCTGCTGCCTTTGAATAAGGAGGAACGTGAGCCAACAGATCCAAGAA
CTGAAGCTCTAGGCAGTGGAAAAGCCAAGGAAACTGATCTTCCCTTCGAGCCTCCGGAGG
GAGTGTAGCCCTGCCAACACCTTTATTTTAGCCCCATAACAGTCATTTCAGACTTGTGGC
CTCCAGAATTTTAAGAGAATAAATTTTTATTGTATTAAGCCATGAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAA
>OriGene 5' read for BC005259 unedited
TAGGATTTTGTAATACGACTCACTATAGGCGGCGCGCGAATTCGCCATTACGGCCGGGGA
AACCTTGATCTGTGAAAGCGGGGGTTTTGGAGGATACCGGAAGTAGAGTCACGGAGAGGT
ATTAAGAAATGGAGAGAAAAATAAGCAGAATCCACCTTGTTTCTGAACCCAGTATAACTC
ATTTTCTACAAGTATCTTGGGAGAAAACACTGGAATCTGGTTTTGTTATTACACTTACTG
ATGGGGATTCANCATGGACTGGGACAGTTTCTGAATCAGAGATTTCCCAAGAAGCTGATG
ACATGGCAATGGAAAAAGGGAAATATGTTGGTGAACTGAGAAAAGCATTGTTGTCAGGAG
CAGGACCAGCTGATGTATACACGTTTAATTTTTCTAAAGAGTCTTGTTATTTCTTCTTTG
AGAAAAACCTGAAAGATGTCTCATTCAGACTTGGTTCCTTCAACCTAGAGAAAGTTGAAA
ACCCAGCTGAAGTCATTAGAGAACTTATTTGTTATTGCTTGGACCCATTGGCAGAAATCA
AGCCAAAATGAGCACCTGCCAAAAGAAATGAAAGGCTTCTGAGAGATGGGATGATGTTCA
AGGACGATTTGAAAAATGTGTGAGTGCTAAGGAAGCTTTGGAGACTGATCTTTATAAGCG
GGTTATTCTGGGGGTGGATGAGAAGGAAACAAAAATCAGAGATGTGGTAATAAATTATTA
AATGCGGCTCAGGAACGAGAAAGGGCCTCAAACAGGAGGGGAAACTGCCATCTGGTCCTG
AATGACTGCTGGCCCAGATCCACTCCATTATGAGGGTCCTGTTAGAGAAATGGAAACCCA
CCCGGTCCCTCTGGGGTGGGTTCCCCTGGGGAAACGAAAAAGAGTCCCTTTTTTCAAGCC
TTGGGGCCCTTGATTTGGCCCACTGAAAAAGGGGCCCGCAATGCGCAAAACCTTGGGGCA
AACCC
Restriction Sites Please inquire     
ACCN BC005259
Insert Size 1300 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq BC005259.1, AAH05259.1
RefSeq Size 1274 bp
Locus ID 7518
Cytogenetics 5q14.2
Protein Families Druggable Genome
Protein Pathways Non-homologous end-joining
Gene Summary 'The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. [provided by RefSeq, Oct 2019]'

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