GPR56 (ADGRG1) (NM_201525) Human Untagged Clone

CAT#: SC126689

GPR56 (untagged)-Human G protein-coupled receptor 56 (GPR56), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADGRG1
• Synonyms: BFPP; BPPR; GPR56; TM7LN4; TM7XN1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126689 sequence for NM_201525 edited (data generated by NextGen Sequencing)
  ATGACTCCCCAGTCGCTGCTGCAGACGACACTGTTCCTGCTGAGTCTGCTCTTCCTGGTC
  CAAGGTGCCCACGGCAGGGGCCACAGGGAAGACTTTCGCTTCTGCAGCCAGCGGAACCAG
  ACACACAGGAGCAGCCTCCACTACAAACCCACACCAGACCTGCGCATCTCCATCGAGAAC
  TCCGAAGAGGCCCTCACAGTCCATGCCCCTTTCCCTGCAGCCCACCCTGCTTCCCGATCC
  TTCCCTGACCCCAGGGGCCTCTACCACTTCTGCCTCTACTGGAACCGACATGCTGGGAGA
  TTACATCTTCTCTATGGCAAGCGTGACTTCTTGCTGAGTGACAAAGCCTCTAGCCTCCTC
  TGCTTCCAGCACCAGGAGGAGAGCCTGGCTCAGGGCCCCCCGCTGTTAGCCACTTCTGTC
  ACCTCCTGGTGGAGCCCTCAGAACATCAGCCTGCCCAGTGCCGCCAGCTTCACCTTCTCC
  TTCCACAGTCCTCCCCACACGGCCGCTCACAATGCCTCGGTGGACATGTGCGAGCTCAAA
  AGGGACCTCCAGCTGCTCAGCCAGTTCCTGAAGCATCCCCAGAAGGCCTCAAGGAGGCCC
  TCGGCTGCCCCCGCCAGCCAGCAGTTGCAGAGCCTGGAGTCGAAACTGACCTCTGTGAGA
  TTCATGGGGGACATGGTGTCCTTCGAGGAGGACCGGATCAACGCCACGGTGTGGAAGCTC
  CAGCCCACAGCCGGCCTCCAGGACCTGCACATCCACTCCCGGCAGGAGGAGGAGCAGAGC
  GAGATCATGGAGTACTCGGTGCTGCTGCCTCGAACACTCTTCCAGAGGACGAAAGGCCGG
  AGGGGGGAGGCTGAGAAGAGACTCCTCCTGGTGGACTTCAGCAGCCAAGCCCTGTTCCAG
  GACAAGAATTCCAGCCAAGTCCTGGGTGAGAAGGTCTTGGGGATTGTGGTACAGAACACC
  AAAGTAGCCAACCTCACGGAGCCCGTGGTGCTCACCTTCCAGCACCAGCTACAGCCGAAG
  AATGTGACTCTGCAATGTGTGTTCTGGGTTGAAGACCCCACATTGAGCAGCCCGGGGCAT
  TGGAGCAGTGCTGGGTGTGAGACCGTCAGGAGAGAAACCCAAACATCCTGCTTCTGCAAC
  CACTTGACCTACTTTGCAGTGCTGATGGTCTCCTCGGTGGAGGTGGACGCCGTGCACAAG
  CACTACCTGAGCCTCCTCTCCTACGTGGGCTGTGTCGTCTCTGCCCTGGCCTGCCTTGTC
  ACCATTGCCGCCTACCTCTGCTCCAGGAGGAAACCTCGGGACTACACCATCAAGGTGCAC
  ATGAACCTGCTGCTGGCCGTCTTCCTGCTGGACACGAGCTTCCTGCTCAGCGAGCCGGTG
  GCCCTGACAGGCTCTGAGGCTGGCTGCCGAGCCAGTGCCATCTTCCTGCACTTCTCCCTG
  CTCACCTGCCTTTCCTGGATGGGCCTCGAGGGGTACAACCTCTACCGACTCGTGGTGGAG
  GTCTTTGGCACCTATGTCCCTGGCTACCTACTCAAGCTGAGCGCCATGGGCTGGGGCTTC
  CCCATCTTTCTGGTGACGCTGGTGGCCCTGGTGGATGTGGACAACTATGGCCCCATCATC
  TTGGCTGTGCATAGGACTCCAGAGGGCGTCATCTACCCTTCCATGTGCTGGATCCGGGAC
  TCCCTGGTCAGCTACATCACCAACCTGGGCCTCTTCAGCCTGGTGTTTCTGTTCAACATG
  GCCATGCTAGCCACCATGGTGGTGCAGATCCTGCGGCTGCGCCCCCACACCCAAAAGTGG
  TCACATGTGCTGACACTGCTGGGCCTCAGCCTGGTCCTTGGCCTGCCCTGGGCCTTGATC
  TTCTTCTCCTTTGCTTCTGGCACCTTCCAGCTTGTCGTCCTCTACCTTTTCAGCATCATC
  ACCTCCTTCCAAGGCTTCCTCATCTTCATCTGGTACTGGTCCATGCGGCTGCAGGCCCGG
  GGTGGCCCCTCCCCTCTGAAGAGCAACTCAGACAGCGCCAGGCTCCCCATCAGCTCGGGC
  AGCACCTCGTCCAGCCGCATCTAG
  
  Clone variation with respect to NM_201525.2
  843 c=>g;996 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005682 unedited
  TAGGGCGGCCCGCGAATTCGCACGAGGGGGAGCAGTGGCTGGGGTGGCCCAGCTTCAAAG
  TCTCTGTCCTCTTGAAAAAGGTGGTCGGGGGACATTGACCCACCAGCCCTGCAGGCTACT
  GCCTGCAAACAAGAACCCCTCATCTGCCACGCACGTTCTTAATGTATCTATAGTCTGCCT
  GATGCCACAAAGGAGTCCAGGTGGTGACTTCCAAGAGTGACTCCGTCGGAGGAAAATGAC
  TCCCCAGTCGCTGCTGCAGACGACACTGTTCCTGCTGAGTCTGCTCTTCCTGGTCCAAGG
  TGCCCACGGCAGGGGCCACAGGGAAGACTTTCGCTTCTGCAGCCAGCGGAACCAGACACA
  CAGGAGCAGCCTCCACTACAAACCCACACCAGACCTGCGCATCTCCATCGAGAACTCCGA
  AGAGGCCCTCACAGTCCATGCCCCTTTCCCTGCAGCCCACCCTGCTTCCCGATCCTTCCC
  TGACCCCAGGGGCCTCTACCACTTCTGCCTCTACTGGAACCGACATGCTGGGAGATTACA
  TCTTCTCTATGGCAAGCGTGACTTCTTGCTGAGTGACAAAGCCTCTAGCCTCCTCTGCTT
  CCAGCACCAGGAGGAGAGCCTGGCTCAGGGCCCCCCGCTGTTAGCCACTTCTGTCACCTC
  CTGGTGGAGCCCTCAGACATCAGCCTGCCCAGTGCCGNCAGCTTCACCTTCTNCTTNCAC
  AGTCCTNCCCACACGGNCGCTCACAATGCCCTCGTGGACATGTGCGAGCTCAAAGGGACC
  TNCAGCTGCTCAGCCCAGTCCTGAAGCATCCCCAGAAGGCCTCAGGNNNAGCCCTCGCTG
  CNNCCCGCAGCCAGCAGTGCAGAGCCTGGAGTCGAACTGACCTTGTGAGATCATGGGGGA
  AATGGTGTCCTCGAGAGGACCGATCACGCCACGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_005682 unedited
  TTGCGNTTACAACGNCTGGTTTTNTTTTTTCTTCTTGATTCTCTTCTACAGTTTCCAAAT
  TCTCTACAATGAACATGTACTTCTTTTTAATATCAAAAGACAAAAGAATTGGTACGTAAA
  AAGAACATCCTTCCCATCTTCAAGGTCAAGATTGAACGCTGACTCCTGCAGGAAGTCTTC
  CAGGATTCCCAGGCAGGAATGATGGCTCCCTGTCCCTGTAGCTCCAGGAGTTCTTGCTTC
  ACGCACGCCTCACATACCAGACTGAATGTTGGCAGGAGGAGTGACCAGGTCGGTCATCTG
  TGTCCCTACCACCTACAACAGGCCAGCAATCTACCCGTGTGTGTTTGTTGGACAGAATTA
  ACCATGATGGGCGGCCGAGGGCGCCTGGAGCTATTTGGGGGCTTGGAGAGAACCTCTTAT
  GAGAGTGTCAGGCTCTATGCCAGTGTCACCAGAGGAGGGCAGTCTCAGTCCTTGGAGTGG
  TGGGATGGAAACCAGACGGGACTGGCATGGTCCACAGTTCTTGCCACAAGAGGGCTTCAG
  GAGAGGCTGAGGGCCCCTCTGAGGCGTGTGCTTGGTCAGGGTGAGCAAGGGCAATGCAGC
  TCATACAAAGGCCCACATGGACAGAGGGACCTAGCNCAGCCCACGCATCGGTACCGAGCC
  TGGCTCATGGGCAGGCCGAGGCTTGTGCAGTTTACAAACATTTACAGCAGACACCAGGCA
  GCTCCTGTAAACCACTCCCCACAAACAGCATTGGAATCGGGGACCCCCACCTGTGTACGA
  AGGAGCAAGAAGGCCCTGGCAGAGGAGGAGAACCCCACGCAAATGGAGGNAGACTGGGGG
  GCTTGGGGAGGAAGGGGGCCTGGGCTCATAGTAGGCGAGCTGCTGCTGTGCTCTGGCAAA
  GGACTTTTCTTCGCCAGGCTCTGCCCTGAAGGATGACCTGGGCCCATACGCCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_201525
• ORF Size: 2064 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_201525.1, NP_958933.1
• RefSeq Size: 3755
• RefSeq ORF: 2064
• Locus ID: 9289
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the coding region compared to variant 4. The resulting isoform (b, also known as S1) is shorter than isoform a. Variants 2, 3, 5, 6, and 7 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.