FBXO3 (NM_012175) Human Untagged Clone

CAT#: SC126716

FBXO3 (untagged)-Human F-box protein 3 (FBXO3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXO3
• Synonyms: FBA; FBX3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126716 sequence for NM_012175 edited (data generated by NextGen Sequencing)
  ATGGCGGCCATGGAGACCGAGACGGCGCCGCTGACCCTAGAGTCGCTGCCCACCGATCCC
  CTGCTCCTCATCTTATCCTTTTTGGACTATCGGGATCTAATCAACTGTTGTTATGTCAGT
  CGAAGACTTAGCCAGCTATCAAGTCATGATCCGCTGTGGAGAAGACATTGCAAAAAATAC
  TGGCTGATATCTGAGGAAGAGAAAACACAGAAGAATCAGTGTTGGAAATCTCTCTTCATA
  GATACTTACTCTGATGTAGGAAGATACATTGACCATTATGCTGCTATTAAAAAGGCCTGG
  GATGATCTCAAGAAATATTTGGAGCCCAGGTGTCCTCGGATGGTTTTATCTCTGAAAGAG
  GGTGCTCGAGAGGAAGACCTCGATGCTGTGGAAGCGCAGATTGGCTGCAAGCTTCCTGAC
  GATTATCGATGTTCATACCGAATTCACAATGGACAGAAGTTAGTGGTTCCTGGGTTATTG
  GGAAGCATGGCACTGTCTAATCACTATCGTTCTGAAGATTTGTTAGACGTCGATACAGCT
  GCCGGAGGATTCCAGCAGAGACAGGGACTGAAATACTGTCTCCCTTTAACTTTTTGCATA
  CATACTGGTTTGAGTCAGTACATAGCAGTGGAAGCTGCAGAGGGCCGAAACAAAAATGAA
  GTTTTCTACCAATGTCCAGACCAAATGGCTCGAAATCCAGCTGCTATTGACATGTTTATT
  ATAGGTGCTACTTTTACTGACTGGTTTACCTCTTATGTCAAAAATGTTGTATCAGGTGGC
  TTCCCCATCATCAGAGACCAAATTTTCAGATATGTTCACGATCCAGAATGTGTAGCAACA
  ACTGGGGATATTACTGTGTCAGTTTCCACATCGTTTCTGCCAGAACTTAGCTCTGTACAT
  CCACCCCACTATTTCTTCACATACCGAATCAGGATTGAAATGTCAAAAGATGCACTTCCT
  GAGAAGGCCTGTCAGTTGGACAGTCGCTATTGGAGAATAACAAATGCTAAGGGTGACGTG
  GAAGAAGTTCAAGGACCTGGAGTAGTTGGTGAATTTCCAATCATCAGCCCAGGTCGGGTA
  TATGAATACACAAGCTGTACCACATTCTCTACAACATCAGGATACATGGAAGGATATTAT
  ACCTTCCATTTTCTTTACTTTAAAGACAAGATCTTTAATGTTGCCATTCCCCGATTCCAT
  ATGGCATGTCCAACATTCAGGGTGTCTATAGCCCGATTGGAAATGGGTCCTGATGAATAT
  GAAGAGATGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAAGACGAGGATGATGATTCAGCA
  GATATGGATGAATCAGATGAAGATGATGAAGAGGAGAGACGGAGGAGAGTCTTTGATGTT
  CCCATTCGCAGACGCCGCTGCTCACGCCTTTTTTAG
  
  Clone variation with respect to NM_012175.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012175 unedited
  ATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGCCAGGCAAGATGGCGGC
  CATGGAGACCGAGACGGCGCCGCTGACCCTAGAGTCGCTGCCCACCGATCCCCTGCTCCT
  CATCTTATCCTTTTTGGACTATCGGGATCTAATCAACTGTTGTTATGTCAGTCGAAGACT
  TAGCCAGCTATCAAGTCATGATCCGCTGTGGAGAAGACATTGCAAAAAATACTGGCTGAT
  ATCTGAGGAAGAGAAAACACAGAAGAATCAGTGTTGGAAATCTCTCTTCATAGATACTTA
  CTCTGATGTAGGAAGATACATTGACCATTATGCTGCTATTAAAAAGGCCTGGGATGATCT
  CAAGAAATATTTGGAGCCCAGGTGTCCTCGGATGGTTTTATCTCTGAAAGAGGGTGCTCG
  AGAGGAAGACCTCGATGCTGTGGAAGCGCAGATTGGCTGCAAGCTTCCTGACGATTATCG
  ATGTTCATACCGAATTCACAATGGACAGAAGTTAGTGGTTCCTGGGTTATTGGGAAGCAT
  GGCACTGTCTAATCACTATCGTTCTGAAGATTTGTTAGACGTCGATACAGCTGCCGGAGG
  ATTCCAGCAGAGACAGGGACTGAAATACTGGTCTCCCTTTAACTTTTTGCATACATACTG
  GTNTTGAGTCAGTACATANCAGTGGAAGCTGCANNAGGCCGAAACAAAATGAAGNTTTCT
  CCAATGTNCCGACCAAATGGCTCGAATCCAGCTGCTATTGACATGTTATTATAGGTGCTA
  CTTTACTGACTGGGTTACCTCTATGTCAAATGTGTATCAGGTGGCTTCCCATCTCAAGAC
  CAATTCAGATTGTTCACATCCAAATGTGAACACACTGGGAATTACTGGGTCAGTTCCACT
  GGTCTGGCGAACCTAATTTGACATCCCCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012175 unedited
  CTATGGACCCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTGCTTTTAAAA
  GTGAGTTTTTAACACTTGGAAGATTTCATTCTTAACTCTCAATTATATAATTACAAAAAA
  AATCCAAGTTTCAGGAAAACATACTTAATCCTAACATAAAATTCATGTCACTTATCACAA
  AGACAGTCAAGTGTATAAAGGAGAAACAAAACAGAAGCAGTATTTACAAATTTAAACTAC
  ATGAGATGTTGTGAACAATCTTTTGTTAATAAACAGCACGTTACATACTTTTACATACTA
  CATTTCAAAAATGCATCTGTGAATAATATGATAAAGCGCATAGTGTTGAAGACTTTAAAT
  TAAATCCAAGGTCATCATGTTGAAGACCTGAAATTAAATTCAAGGTTGTAGTGATGAAAA
  ATTTAAAGTCAAGGTCTTAGCGATAAAGACTTTAAATTCAAAGACAGATTGTCTAAGGAC
  AAACCACTAGCGTTCAAGTTGTTTAGTCAATTAGTTCTCTGTGAGTACAAAATATTAGGA
  ATCACTAAATGGATTAGCCTAATTACAAATTTTGATCATTTCTAAATAACTCACAACTGC
  AAGAAGTCTTTTCACAGAATGAGTCACATAGTTTCTCTCTATCCTTGTGCAGGTATTTTA
  AATCCTTATTCAAAACAGTTCCCTCTCCATTTCTAGATTTTTGTAAGTATAAAATATTTT
  AAAACAAAGGTATGTCCGTTCCTTATCTAGAGAACTATTCTTCCACTGACTCCTGGAAAA
  GAAAAAAAGATTCCATTTCTTCCTCTACCTCAAAAACCAAAGCAAACCCAAACAATCCAT
  TCCTAATGTAGTGTCCATAGAACCCAAGGCCTGAACAAATTTCATGCTAGNTTTCCTGCA
  TATGCANAGACCAATTAGTTATTAATTATTGAGAAACTATTAAAGGCTAGATCATCCTAA
  GCTTCCTCACAGAAAGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012175
• ORF Size: 1416 bp
• Insert Size: 2440
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_012175.3, NP_036307.2
• RefSeq Size: 2408
• RefSeq ORF: 1416
• Locus ID: 26273
• Domains: F-box, DUF525
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1) which includes a highly acidic D/E-rich domain and two poly-R pieces at the C-terminus.