HNRPAB (HNRNPAB) (NM_004499) Human Untagged Clone

CAT#: SC127447

HNRNPAB (untagged)-Human heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HNRNPAB
• Synonyms: ABBP1; HNRPAB
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127447 sequence for NM_004499 edited (data generated by NextGen Sequencing)
  ATGTCGGAAGCGGGCGAGGAGCAGCCCATGGAGACGACGGGCGCCACCGAGAACGGACAT
  GAGGCCGTCCCCGAAGGCGAGTCGCCGGCCGGGGCTGGCACGGGCGCCGCGGCGGGGGCT
  GGAGGCGCGACCGCGGCGCCCCCGAGCGGGAATCAGAACGGCGCCGAGGGCGACCAGATC
  AACGCCAGCAAGAACGAGGAGGACGCGGGAAAAATGTTCGTTGGTGGCCTGAGCTGGGAT
  ACTAGCAAAAAAGATTTAAAAGACTATTTTACTAAATTTGGAGAGGTCGTTGACTGTACA
  ATAAAAATGGATCCCAACACTGGACGGTCAAGAGGGTTTGGGTTTATCCTGTTCAAAGAT
  GCAGCCAGTGTGGAGAAGGTCCTAGACCAGAAGGAGCACAGGCTGGATGGCCGTGTCATT
  GACCCTAAAAAGGCCATGGCTATGAAGAAGGACCCGGTGAAGAAAATCTTCGTTGGGGGT
  CTGAATCCTGAAGCCACTGAGGAAAAGATCAGGGAGTACTTTGGCGAGTTTGGGGAGATT
  GAGGCCATTGAATTGCCAATGGATCCAAAGTTGAACAAAAGACGAGGTTTTGTGTTTATC
  ACCTTTAAAGAAGAAGAACCCGTGAAGAAGGTTCTGGAGAAAAAGTTCCATACTGTCAGT
  GGAAGCAAGTGTGAGATCAAGGTGGCCCAGCCCAAAGAAGTCTATCAGCAGCAGCAGTAT
  GGCTCTGGGGGCCGTGGAAACCGCAACCGAGGGAACCGAGGCAGCGGAGGTGGTGGTGGA
  GGTGGAGGTCAGGGTAGTACAAACTACGGCAAGAGCCAGCGACGTGGTGGCCATCAGAAT
  AACTACAAGCCATACTGA
  
  Clone variation with respect to NM_004499.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004499 unedited
  GTTCAAATTTTGTAATACGACTCACTATAGGGCGGCNCGCGAATTCGCACGAGGCCGCGC
  GGGACGGAGCTTGGCTGTTGGTCGGTGGGTTCCCGTGCGGCGGCGGCCAAGGAGGAGGAG
  ACACAGTTGGAGCAGCTCCGTGGGCTGACTGGGGCGAGGCCTCAGCAGCGCGAGCTTGAG
  TGCGGCCGAGCCTGCGGCGCCTTCCCCTGCGGGTGGGGACGAGCGGGCCCCGCGGCGTCA
  TCGGCGGCGAGGAGCCGCCGCGCCTCGGCCTAGCATGTCGGAAGCGGGCGAGGAGCAGCC
  CATGGAGACGACGGGCGCCACCGAGAACGGACATGAGGCCGTCCCCGAAGGCGAGTCGCC
  GGCCGGGGCTGGCACGGGGCGCCGCGGCGGGGGCTGGAGGCGCGACCGCGGCGCCCCCGA
  GCGGGAATCAGAACGGCGCCGAGGGCGACCAGATCAACGCCAGCAAGAACGAGGAGGACG
  CGGGAAAAATGTTCGTTGGTGGCCTGAGCTGGGATACTAGCAAAAAAGATTTAAAAGACT
  ATTTTACTAAATTTGGGAGAGGGTCGTTGACTGTACAATAAAAATGGATCCCAACACTGG
  ACGGTCAAGAGGGTTTTGGGGTTTATTCCTGTTCAAAGATGCAGCCAGTGTGGNAGAAGG
  TCCTAGACCAGAAGGAGCACAGGCCTGGATGGGCCGTGTCATTGACCCTTAAAAGGCCAT
  GGCTTGNAAAGAAGACCCGGTGAAGAAATCTTCCGTAGGGGGGTCTGAATCCCTGAGCCA
  CTGAGGAAAGATCAGGGAGTACTTGGCCGAGGTTGGGGGGAGAATGAGGCCATTGAATGC
  CAATGGATCCCAAGTGACAAAAAACAGGGGTTTTTGGGGTTATCACTTTAAAGAGAAGAC
  CGGGGAAAAAAAGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004499 unedited
  GGTCTTAAATCTTTTTAAAGCTTGGCTAGCTTCAATTCCAGTTGTGGCAAAATTATGACA
  CGTGTAAAATACCTTACAATACATTAGATTCCCAAAGGTACCAAAAGTACAGTAAAATTA
  ACACTTCCGTTACAGGAAATGTATGACGCAAATAATATAAAATTAAAAGGTGAAAAAAAG
  GTGACACTGGTTTCCTAAGATACAATTTACTCTTTACAACCAGGGTCCACAGGTCCAGGC
  TGCAGAGCGGCAGCAGGAAGCAGAGCCTCCCACCTGCTTCTGGGGGACCTGGTAATAAAA
  ATCAGCCCATGATGGCGCTATGGCCTCTCAGACACCACACGCTGCCTAAACACCTAGAGC
  TCTGGAAATAGTCAACAGGAGAGTGATTTCCATGGGGGAAATTTTAAATAAGATGCACAT
  GGGACAGGCAATAGAAAGTTTGCCAAGTTAAATTTGGTACATAATTGTGTTCACTCCATA
  TCCAAACAAAGCATGTGTGCGATCAGTTGGTCGCTCCTGCTGCCGCCTCAGTATGGCTTG
  TAGTTATTCTGATGGCCACCACGTCGCTGGCTCTCGCCGTAGTTCGTACTACCCTGACTG
  TAGTCGTAGCCGGGGCCGTACCCGTAATAGCCATACGGCGAGCACTCCGAGCCGCCATAT
  TAGGCCCGTAGCCCTGCTGGCACCTGTACCCCTGGTTTCACGCGCCTGTCGCAATCCTTG
  ATTCCAACTTCGACTTTTGATTCTTCACCTTACCANTACCTCCGCCTGCCTCCGGTTCTT
  CGGTTGCTGGTTCCACGGGCCCCACAACCCTACTGGCTGCTGCTGTAGGAATTTTTGTCG
  CCTGGCCACCTTTGATCTCCCCTTNGCTTCACTGACATTCGGGACACTTTTTCCAGAACC
  TTCTTACGGCTNCCTTTTCTTTAAGTGATAAACCACCCCCCCCCTTTGCTACCTTTGTTC
  TTGCCACTCACGGCCTCACTCCTTATTCTCCAACCCCCGTACTCTCTAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004499
• Insert Size: 1820 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004499.3, NP_004490.2
• RefSeq Size: 1696 bp
• RefSeq ORF: 858 bp
• Locus ID: 3182
• Cytogenetics: 5q35.3
• Domains: RRM
• Gene Summary: 'This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region compared to variant 1. The resulting protein (isoform b) is shorter, compared to isoform a.