FNIP1 (NM_001008738) Human Untagged Clone

CAT#: SC301360

FNIP1 (untagged)-Human folliculin interacting protein 1 (FNIP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FNIP1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001008738, the custom clone sequence may differ by one or more nucleotides
  ATGGCCCCTACGCTGTTCCAGAAGCTCTTCAGCAAGAGGACCGGGCTGGGCGCGCCCGGC
  CGCGACGCCCGGGACCCAGATTGCGGGTTCAGTTGGCCTTTACCAGAGTTTGATCCAAGC
  CAGATTCGACTGATTGTATATCAAGACTGTGAAAGACGAGGGAGAAATGTTTTGTTTGAC
  TCCAGTGTTAAGAGAAGAAATGAGGACATATCAGTATCGAAACTCTGCAGTGATGCTCAA
  GTTAAAGTCTTTGGGAAATGCTGCCAACTGAAACCTGGAGGAGACAGTTCTTCCTCTTTA
  GATAGTTCTGTGACTTCATCTTCTGATATAAAAGACCAGTGTCTTAAGTACCAGGGTTCT
  CGGTGCTCTTCTGATGCCAATATGCTTGGAGAGATGATGTTTGGCTCAGTAGCAATGAGC
  TACAAAGGATCCACCTTAAAAATTCATCAGATTCGTTCCCCTCCACAGCTCATGCTCAGC
  AAAGTGTTTACTGCTCGGACTGGCAGCAGTATTTGTGGGAGTCTCAATACGCTACAAGAT
  AGTCTTGAATTCATCAATCAGGACAACAATACATTAAAGGCTGATAATAACACAGTTATT
  AATGGACTGCTTGGAAATATAGTTCACAGCAACCCAATGGACATGCCTGGAAGAGAGCTC
  AATGAGGACAGAGACAGTGGCATAGCACGGTCTGCATCTCTCAGCAGCTTGCTGATCACT
  CCATTTCCTTCCCCAAACTCCTCACTTACCCGAAGTTGTGCCAGCAGCTACCAGCGACGT
  TGGCGACGCAGCCAAACAACAAGTTTGGAAAATGGGGTATTTCCTAGATGGTCTATAGAA
  GAAAGCTTTAATCTCTCAGATGAAAGCTGTGGCCCTAACCCAGGAATTGTGCGGAAAAAG
  AAGATTGCAATTGGGGTAATCTTTTCATTGTCCAAAGATGAAGATGAAAATAACAAATTT
  AATGAATTCTTTTTTTCACATTTTCCTCTCTTTGAAAGCCACATGAACAAATTAAAGAGT
  GCAATAGAACAGGCTATGAAAATGAGCCGGAGATCAGCTGATGCCAGTCAGAGAAGTTTG
  GCATATAATCGAATAGTTGATGCCCTAAATGAATTCAGAACAACAATTTGTAATCTTTAC
  ACGATGCCACGAATTGGAGAACCTGTCTGGCTTACAATGATGTCGGGGACTCCAGAAAAG
  AACCACCTTTGCTATCGTTTCATGAAGGAGTTCACCTTTCTAATGGAAAATGCTTCCAAA
  AATCAATTCTTGCCAGCTCTCATTACTGCAGTTCTGACCAATCATCTTGCCTGGGTTCCA
  ACAGTCATGCCAAATGGACAACCACCTATAAAAATATTTTTAGAAAAGCATTCCTCTCAG
  AGTGTGGACATGTTGGCAAAGACTCATCCATATAACCCACTTTGGGCACAACTGGGAGAC
  TTGTATGGCGCTATTGGCTCTCCCGTACGGTTAGCAAGGACTGTGGTAGTTGGCAAACGA
  CAAGACATGGTCCAGAGGCTACTTTATTTTCTTACTTATTTTATAAGATGCTCTGAACTT
  CAAGAAACGCATCTTTTAGAAAATGGAGAAGATGAAGCCATCGTTATGCCAGGCACAGTA
  ATTACTACCACTTTAGAGAAAGGTGAAATAGAAGAATCAGAGTATGTCCTTGTCACAATG
  CATAGAAACAAAAGCAGTTTGCTCTTTAAAGAGTCAGAAGAAATTAGAACTCCCAATTGT
  AACTGTAAATATTGCAGTCATCCACTCCTTGGGCAAAATGTAGAGAACATTTCACAACAA
  GAGAGAGAAGATATTCAAAACAGCTCTAAGGAGCTGCTAGGAATTTCAGATGAGTGCCAG
  ATGATTTCTCCTTCTGACTGCCAAGAAGAAAATGCTGTTGATGTTAAACAGTACAGAGAT
  AAATTAAGAACTTGCTTTGACGCCAAGTTAGAGACAGTTGTTTGCACAGGATCTGTTCCA
  GTAGACAAATGTGCATTGTCAGAGTCAGGCTTAGAGTCAACAGAGGAAACATGGCAGAGT
  GAGAAGTTGCTGGATTCAGACAGTCACACAGGCAAAGCAATGAGATCCACAGGAATGGTT
  GTGGAAAAAAAACCTCCAGATAAGATTGTGCCTGCTTCATTTTCTTGTGAGGCTGCCCAG
  ACAAAGGTTACTTTCCTGATTGGGGATTCTATGTCACCTGATTCAGATACTGAGCTTCGA
  AGTCAGGCAGTGGTGGATCAGATTACCAGACATCACACCAAACCATTGAAGGAAGAAAGA
  GGGGCTATTGATCAGCATCAAGAAACTAAACAAACAACCAAGGACCAATCTGGAGAGTCT
  GATACACAGAACATGGTTTCTGAAGAGCCCTGTGAACTTCCCTGTTGGAATCATTCAGAC
  CCAGAAAGCATGAGCTTATTCGACGAATATTTTAATGATGATTCAATCGAAACCAGGACT
  ATTGATGATGTTCCATTTAAAACAAGTACAGATAGTAAAGACCATTGCTGTATGTTAGAG
  TTTTCAAAAATATTGTGTACAAAAAATAACAAGCAGAACAATGAATTTTGTAAATGTATA
  GAAACAGTTCCCCAAGATTCATGTAAAACCTGCTTTCCTCAGCAGGACCAAAGAGATACA
  CTCTCCATTCTTGTCCCCCATGGGGATAAAGAGAGTTCAGATAAAAAAATTGCTGTAGGA
  ACTGAATGGGACATTCCAAGAAATGAAAGTTCAGACAGTGCCCTTGGGGATAGTGAAAGT
  GAAGATACAGGTCATGATATGACTAGACAAGTTAGCAGTTATTATGGAGGAGAGCAAGAA
  GATTGGGCAGAAGAGGATGAGATACCTTTTCCTGGGTCAAAGTTAATCGAAGTGAGTGCT
  GTTCAGCCCAACATTGCCAACTTCGGGAGGTCCTTGCTGGGTGGCTACTGCTCATCTTAT
  GTGCCTGACTTTGTTCTTCAAGGAATTGGGAGTGATGAGAGGTTCCGTCAGTGTCTGATG
  TCAGATTTATCTCATGCTGTGCAGCATCCAGTTTTGGATGAACCAATAGCAGAAGCTGTC
  TGTATTATAGCTGACATGGATAAATGGACTGTTCAAGTGGCCAGTAGCCAGAGACGAGTG
  ACAGATAATAAATTGGGAAAGGAAGTATTGGTTTCCAGTCTTGTTTCCAATCTGCTTCAT
  TCCACACTTCAGCTTTATAAGCATAACTTGTCTCCAAATTTTTGTGTAATGCATCTTGAA
  GACCGGTTGCAGGAGCTATACTTCAAAAGTAAAATGCTGTCTGAATACCTGAGGGGGCAG
  ATGCGTGTTCATGTCAAGGAGCTGGGAGTGGTTCTGGGGATTGAATCCAGTGATCTTCCA
  CTTCTGGCTGCTGTAGCAAGCACTCACTCTCCATATGTTGCACAAATACTCCTTTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001008738
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001008738.1, NP_001008738.1
• RefSeq Size: 6500 bp
• RefSeq ORF: 3417 bp
• Locus ID: 96459
• Cytogenetics: 5q31.1
• Gene Summary: This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1, which results in a shorter protein (isoform 2), compared to isoform 1.