Cyclin C (CCNC) (NM_001013399) Human Untagged Clone

CAT#: SC301777

CCNC (untagged)-Human cyclin C (CCNC), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCNC
• Synonyms: CycC; hSRB11; SRB11
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001013399, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCCTACATGTGTGTTTTTGGCATCCAAAGTAGAGGAATTTGGAGTAGTTTCAAATACAAGATTGA
  TTGCTGCTGCTACTTCTGTATTAAAAACTAGATTTTCATATGCCTTTCCAAAGGAATTTCCTTATAGGAT
  GAATCATATATTAGAATGTGAATTCTATCTGTTAGAACTAATGGATTGTTGCTTGATAGTGTATCATCCT
  TATAGACCTTTGCTCCAGTATGTGCAGGACATGGGCCAAGAAGACATGTTGCTTCCCCTTGCATGGAGGA
  TAGTGAATGATACCTACAGAACGGATCTTTGCCTACTGTATCCTCCTTTCATGATAGCTTTAGCTTGCCT
  ACATGTAGCCTGTGTTGTACAGCAGAAAGATGCCAGGCAATGGTTTGCTGAGCTTTCTGTGGATATGGAA
  AAGATTTTGGAAATAATCAGGGTTATTTTAAAACTATATGAGCAGTGGAAGAATTTCGATGAGAGAAAAG
  AGATGGCAACCATTCTTAGTAAGATGCCAAAACCAAAACCACCTCCAAACAGTGAAGGAGAGCAGGGTCC
  AAATGGAAGTCAGAACTCTAGCTACAGCCAATCTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001013399
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001013399.1, NP_001013417.1
• RefSeq Size: 2099 bp
• RefSeq ORF: 597 bp
• Locus ID: 892
• Cytogenetics: 6q16.2
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) uses an alternate splice site compared to variant 1, that results in the use of a downstream translational start codon. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.