ABCA2 (NM_001606) Human Untagged Clone

CAT#: SC303047

ABCA2 (untagged)-Human ATP-binding cassette, sub-family A (ABC1), member 2 (ABCA2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCA2
• Synonyms: ABC2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001606, the custom clone sequence may differ by one or more nucleotides
  ATGGGCTTCCTGCACCAGCTGCAGCTGCTGCTCTGGAAGAACGTGACGCTCAAACGCCGG
  AGCCCGTGGGTCCTGGCCTTCGAGATCTTCATCCCCCTGGTGCTGTTCTTTATCCTGCTG
  GGGCTGCGACAGAAGAAGCCCACCATCTCCGTGAAGGAAGTCTCCTTCTACACAGCGGCG
  CCCCTGACGTCTGCCGGCATCCTGCCTGTCATGCAATCGCTGTGCCCGGACGGCCAGCGA
  GACGAGTTCGGCTTCCTGCAGTACGCCAACTCCACGGTCACGCAGCTGCTTGAGCGCCTG
  GACCGCGTGGTGGAGGAAGGCAACCTGTTTGACCCAGCGCGGCCCAGCCTGGGCTCAGAG
  CTCGAGGCCCTACGCCAGCATCTGGAGGCCCTCAGTGCGGGCCCGGGCACCTCGGGGAGC
  CACCTGGACAGATCCACAGTGTCTTCCTTCTCTCTGGACTCGGTGGCCAGAAACCCGCAG
  GAGCTCTGGCGTTTCCTGACGCAAAACTTGTCGCTGCCCAATAGCACGGCCCAAGCACTC
  TTGGCCGCCCGTGTGGACCCGCCCGAGGTCTACCACCTGCTCTTTGGTCCCTCATCTGCC
  CTGGATTCACAGTCTGGCCTCCACAAGGGTCAGGAGCCCTGGAGCCGCCTAGGGGGCAAT
  CCCCTGTTCCGGATGGAGGAGCTGCTGCTGGCTCCTGCCCTCCTGGAGCAGCTCACCTGC
  ACGCCGGGCTCGGGGGAGCTGGGCCGGATCCTCACTGTGCCTGAGAGTCAGAAGGGAGCC
  CTGCAGGGCTACCGGGATGCTGTCTGCAGTGGGCAGGCTGCTGCGCGTGCCAGGCGCTTC
  TCTGGGCTGTCTGCTGAGCTCCGGAACCAGCTGGACGTGGCCAAGGTCTCCCAGCAGCTG
  GGCCTGGATGCCCCCAACGGCTCGGACTCCTCGCCACAGGCGCCACCCCCACGGAGGCTG
  CAGGCGCTTCTGGGGGACCTGCTGGATGCCCAGAAGGTTCTGCAGGATGTGGATGTCCTG
  TCGGCCCTGGCCCTGCTACTGCCCCAGGGTGCCTGCACTGGCCGGACCCCCGGACCCCCA
  GCCAGTGGTGCGGGTGGGGCGGCCAATGGCACTGGGGCAGGGGCAGTCATGGGCCCCAAC
  GCCACCGCTGAGGAGGGCGCACCCTCTGCTGCAGCACTGGCCACCCCGGACACGCTGCAG
  GGCCAGTGCTCAGCCTTCGTACAGCTCTGGGCCGGCCTGCAGCCCATCTTGTGTGGCAAC
  AACCGCACCATTGAACCCGAGGCGCTGCGGCGGGGCAACATGAGCTCCCTGGGCTTCACG
  AGCAAGGAGCAGCGGAACCTGGGCCTCCTCGTGCACCTCATGACCAGCAACCCCAAAATC
  CTGTACGCGCCTGCGGGCTCTGAGGTCGACCGCGTCATCCTCAAGGCCAACGAGACTTTT
  GCTTTTGTGGGCAACGTGACTCACTATGCCCAGGTCTGGCTCAACATCTCGGCGGAGATC
  CGCAGCTTCCTGGAGCAGGGCAGGCTGCAGCAACACCTGCGCTGGCTGCAGCAGTATGTA
  GCAGAGCTGCGGCTGCACCCCGAGGCACTGAACCTGTCACTGGATGAGCTGCCGCCGGCC
  CTGAGACAGGACAACTTCTCGCTGCCCAGTGGCATGGCCCTCCTGCAGCAGCTGGATACC
  ATTGACAACGCGGCCTGCGGCTGGATCCAGTTCATGTCCAAGGTGAGCGTGGACATCTTC
  AAGGGCTTCCCCGACGAGGAGAGCATTGTCAACTACACCCTCAACCAGGCCTACCAGGAC
  AACGTCACTGTTTTTGCCAGTGTGATCTTCCAGACCCGGAAGGACGGCTCGCTCCCGCCT
  CACGTGCACTACAAGATCCGCCAGAACTCCAGCTTCACCGAGAAAACCAACGAGATCCGC
  CGCGCCTACTGGCGGCCTGGGCCCAATACTGGCGGCCGCTTCTACTTCCTCTACGGCTTC
  GTCTGGATCCAGGACATGATGGAGCGCGCCATCATCGACACTTTTGTGGGGCACGATGTG
  GTGGAGCCAGGCAGCTACGTGCAGATGTTCCCCTACCCCTGCTACACACGCGATGACTTC
  CTGTTTGTCATTGAGCACATGATGCCGCTGTGCATGGTGATCTCCTGGGTCTACTCCGTG
  GCCATGACCATCCAGCACATCGTGGCGGAGAAGGAGCACCGGCTCAAGGAGGTGATGAAG
  ACCATGGGCCTGAACAACGCGGTGCACTGGGTGGCCTGGTTCATCACCGGCTTTGTGCAG
  CTGTCCATCTCCGTGACAGCACTCACCGCCATCCTGAAGTACGGCCAGGTGCTTATGCAC
  AGCCACGTGGTCATCATCTGGCTCTTCCTGGCAGTCTACGCGGTGGCCACCATCATGTTC
  TGCTTCCTGGTGTCTGTGCTGTACTCCAAGGCCAAGCTGGCCTCGGCCTGCGGTGGCATC
  ATCTACTTCCTGAGCTACGTGCCCTACATGTACGTGGCGATCCGAGAGGAGGTGGCGCAT
  GATAAGATCACGGCCTTCGAGAAGTGCATCGCGTCCCTCATGTCCACGACGGCCTTTGGT
  CTGGGCTCTAAGTACTTCGCGCTGTATGAGGTGGCCGGCGTGGGCATCCAGTGGCACACC
  TTCAGCCAGTCCCCGGTGGAGGGGGACGACTTCAACTTGCTCCTGGCTGTCACCATGCTG
  ATGGTGGACGCCGTGGTCTATGGCATCCTCACGTGGTACATTGAGGCTGTGCACCCAGGC
  ATGTACGGGCTGCCCCGGCCCTGGTACTTCCCACTGCAGAAGTCCTACTGGCTGGGCAGT
  GGGCGGACAGAAGCCTGGGAGTGGAGCTGGCCGTGGGCACGCACCCCCCGCCTCAGTGTC
  ATGGAGGAGGACCAGGCCTGTGCCATGGAGAGCCGGCGCTTTGAGGAGACCCGTGGCATG
  GAGGAGGAGCCCACCCACCTGCCTCTGGTTGTCTGCGTGGACAAACTCACCAAGGTCTAC
  AAGGACGACAAGAAGCTGGCCCTGAACAAGCTGAGCCTGAACCTCTACGAGAACCAGGTG
  GTCTCCTTCTTGGGCCACAACGGGGCGGGCAAGACCACCACCATGTCCATCCTGACCGGC
  CTGTTCCCTCCAACGTCGGGTTCCGCCACCATCTACGGGCACGACATCCGCACGGAGATG
  GATGAGATCCGCAAGAACCTGGGCATGTGCCCGCAGCACAATGTGCTCTTTGACCGGCTC
  ACGGTGGAGGAACACCTCTGGTTCTACTCACGGCTCAAGAGCATGGCTCAGGAGGAGATC
  CGCAGAGAGATGGACAAGATGATCGAGGACCTGGAGCTCTCCAACAAACGGCACTCACTG
  GTGCAGACATTGTCGGGTGGCATGAAGCGCAAGCTGTCCGTGGCCATCGCCTTCGTGGGC
  GGCTCTCGCGCCATCATCCTGGACGAGCCCACGGCGGGCGTGGACCCCTACGCGCGCCGC
  GCCATCTGGGACCTCATCCTGAAGTACAAGCCAGGCCGCACCATCCTTCTGTCCACCCAC
  CACATGGATGAGGCTGACCTGCTTGGGGACCGCATTGCCATCATCTCCCATGGGAAGCTC
  AAGTGCTGCGGCTCCCCGCTCTTCCTCAAGGGCACCTATGGCGACGGGTACCGCCTCACG
  CTGGTCAAGCGGCCCGCCGAGCCGGGGGGCCCCCAAGAGCCAGGGCTGGCATCCAGCCCC
  CCAGGTCGGGCCCCGCTGAGCAGCTGCTCCGAGCTCCAGGTGTCCCAGTTCATCCGCAAG
  CATGTGGCCTCCTGCCTGCTGGTCTCAGACACAAGCACGGAGCTCTCCTACATCCTGCCC
  AGCGAGGCCGCCAAGAAGGGGGCTTTCGAGCGCCTCTTCCAGCACCTGGAGCGCAGCCTG
  GATGCACTGCACCTCAGCAGCTTCGGGCTGATGGACACGACCCTGGAGGAAGTGTTCCTC
  AAGGTGTCGGAGGAGGATCAGTCGCTGGAGAACAGTGAGGCCGATGTGAAGGAGTCCAGG
  AAGGATGTGCTCCCTGGGGCGGAGGGCCCGGCGTCTGGGGAGGGTCACGCTGGCAATCTG
  GCCCGGTGCTCGGAGCTGACCCAGTCGCAGGCATCGCTGCAGTCGGCGTCATCTGTGGGC
  TCTGCCCGTGGCGACGAGGGAGCTGGCTACACCGACGTCTATGGCGACTACCGCCCCCTC
  TTTGATAACCCACAGGACCCAGACAATGTCAGCCTGCAAGAGGTGGAGGCAGAGGCCCTG
  TCGAGGGTCGGCCAGGGCAGCCGCAAGCTGGACGGCGGGTGGCTGAAGGTGCGCCAGTTC
  CACGGGCTGCTGGTCAAACGCTTCCACTGCGCCCGCCGCAACTCCAAGGCACTCTTCTCC
  CAGATCTTGCTGCCAGCCTTCTTCGTCTGCGTGGCCATGACCGTGGCCCTGTCCGTCCCG
  GAGATTGGTGATCTGCCCCCGCTGGTCCTGTCACCTTCCCAGTACCACAACTACACCCAG
  CCCCGTGGCAATTTCATCCCCTACGCCAACGAGGAGCGCCGCGAGTACCGGCTGCGGCTA
  TCGCCCGACGCCAGCCCCCAGCAGCTCGTGAGCACGTTCCGGCTGCCGTCGGGGGTGGGT
  GCCACCTGCGTGCTCAAGTCTCCCGCCAACGGCTCGCTGGGGCCCACGTTGAACCTGAGC
  AGCGGGGAGTCGCGCCTGCTGGCGGCTCGGTTCTTCGACAGCATGTGTCTGGAGTCCTTC
  ACACAGGGGCTGCCACTGTCCAATTTCGTGCCACCCCCACCCTCGCCCGCCCCATCTGAC
  TCGCCAGCGTCCCCGGATGAGGACCTGCAGGCCTGGAACGTCTCCCTGCCGCCCACCGCT
  GGGCCAGAAATGTGGACGTCGGCACCCTCCCTGCCGCGCCTGGTACGGGAGCCCGTCCGC
  TGCACCTGCTCTGCGCAGGGCACCGGCTTCTCCTGCCCCAGCAGTGTGGGCGGGCACCCG
  CCCCAGATGCGGGTGGTCACAGGCGACATCCTGACCGACATCACCGGCCACAATGTCTCT
  GAGTACCTGCTCTTCACCTCCGACCGCTTCCGACTGCACCGGTATGGGGCCATCACCTTT
  GGAAACGTCCTGAAGTCCATCCCAGCCTCATTTGGCACCAGGGCCCCACCCATGGTGCGG
  AAGATCGCGGTGCGCAGGGCTGCCCAGGTTTTCTACAACAACAAGGGCTATCACAGCATG
  CCCACCTACCTCAACAGCCTCAACAACGCCATCCTGCGTGCCAACCTGCCCAAGAGCAAG
  GGCAACCCGGCGGCTTACGGCATCACCGTCACCAACCACCCCATGAATAAGACCAGCGCC
  AGCCTCTCCCTGGATTACCTGCTGCAGGGCACGGATGTCGTCATCGCCATCTTCATCATC
  GTGGCCATGTCCTTCGTGCCGGCCAGCTTCGTTGTCTTCCTCGTGGCCGAGAAGTCCACC
  AAGGCCAAGCACCTGCAGTTTGTCAGCGGCTGCAACCCCATCATCTACTGGCTGGCGAAC
  TACGTGTGGGACATGCTCAACTACCTGGTCCCCGCTACCTGCTGTGTCATCATCCTGTTT
  GTGTTCGACCTGCCGGCCTACACGTCGCCCACCAACTTCCCTGCCGTCCTCTCCCTCTTC
  CTGCTCTATGGGTGGTCCATCACGCCCATCATGTACCCGGCCTCCTTCTGGTTCGAGGTC
  CCCAGCTCCGCCTACGTGTTCCTCATTGTCATCAATCTCTTCATCGGCATCACCGCCACC
  GTGGCCACCTTCCTGCTACAGCTCTTCGAGCACGACAAGGACCTGAAGGTTGTCAACAGT
  TACCTGAAAAGCTGCTTCCTCATTTTCCCCAACTACAACCTGGGCCACGGGCTCATGGAG
  ATGGCCTACAACGAGTACATCAACGAGTACTACGCCAAGATTGGCCAGTTTGACAAGATG
  AAGTCCCCGTTCGAGTGGGACATTGTCACCCGCGGACTGGTGGCCATGGCGGTTGAGGGC
  GTCGTGGGCTTCCTCCTGACCATCATGTGCCAGTACAACTTCCTGCGGCGGCCACAGCGC
  ATGCCTGTGTCTACCAAGCCTGTGGAGGATGATGTGGACGTGGCCAGTGAGCGGCAGCGA
  GTGCTCCGGGGAGACGCCGACAATGACATGGTCAAGATTGAGAACCTGACCAAGGTCTAC
  AAGTCCCGGAAGATTGGCCGTATCCTGGCCGTTGACCGCCTGTGCCTGGGTGTGCGTCCT
  GGCGAGTGCTTCGGGCTCCTGGGCGTCAACGGTGCGGGCAAGACCAGCACCTTCAAGATG
  CTGACCGGCGACGAGAGCACGACGGGGGGCGAGGCCTTCGTCAATGGACACAGCGTGCTG
  AAGGAGCTGCTCCAGGTGCAGCAGAGCCTCGGCTACTGCCCGCAGTGTGACGCGCTGTTC
  GACGAGCTCACGGCCCGGGAGCACCTGCAGCTGTACACGCGGCTGCGTGGGATCTCCTGG
  AAGGACGAGGCCCGGGTGGTGAAGTGGGCTCTGGAGAAGCTGGAGCTGACCAAGTACGCA
  GACAAGCCGGCTGGCACCTACAGCGGCGGCAACAAGCGGAAGCTCTCCACGGCCATCGCC
  CTCATTGGGTACCCAGCCTTCATCTTCCTGGACGAGCCCACCACAGGCATGGACCCCAAG
  GCCCGGCGCTTCCTCTGGAACCTCATCCTTGACCTCATCAAGACAGGGCGTTCAGTGGTG
  CTGACATCACACAGCATGGAGGAGTGCGAGGCGCTGTGCACGCGGCTGGCCATCATGGTG
  AACGGTCGCCTGCGGTGCCTGGGCAGCATCCAGCACCTGAAGAACCGGTTTGGAGATGGC
  TACATGATCACGGTGCGGACCAAGAGCAGCCAGAGTGTGAAGGACGTGGTGCGGTTCTTC
  AACCGCAACTTCCCGGAAGCCATGCTCAAGGAGCGGCACCACACAAAGGTGCAGTACCAG
  CTCAAGTCGGAGCACATCTCGCTGGCCCAGGTGTTCAGCAAGATGGAGCAGGTGTCTGGC
  GTGCTGGGCATCGAGGACTACTCGGTCAGCCAGACCACACTGGACAATGTGTTCGTGAAC
  TTTGCCAAGAAGCAGAGTGACAACCTGGAGCAGCAGGAGACGGAGCCGCCATCCGCACTG
  CAGTCCCCTCTCGGCTGCTTGCTCAGCCTGCTCCGGCCCCGGTCTGCCCCCACGGAGCTC
  CGGGCACTTGTGGCAGACGAGCCCGAGGACCTGGACACGGAGGACGAGGGCCTCATCAGC
  TTCGAGGAGGAGCGGGCCCAGCTGTCCTTCAACACGGACACGCTCTGCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001606
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001606.3, NP_001597.2
• RefSeq Size: 8172 bp
• RefSeq ORF: 7311 bp
• Locus ID: 20
• Cytogenetics: 9q34.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters, Lysosome
• Gene Summary: 'The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the predominant isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene.