Exonuclease 1 (EXO1) (NM_003686) Human Untagged Clone

CAT#: SC303363

EXO1 (untagged)-Human exonuclease 1 (EXO1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXO1
• Synonyms: HEX1; hExoI
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003686, the custom clone sequence may differ by one or more nucleotides
  ATGGGGATACAGGGATTGCTACAATTTATCAAAGAAGCTTCAGAACCCATCCATGTGAGG
  AAGTATAAAGGGCAGGTAGTAGCTGTGGATACATATTGCTGGCTTCACAAAGGAGCTATT
  GCTTGTGCTGAAAAACTAGCCAAAGGTGAACCTACTGATAGGTATGTAGGATTTTGTATG
  AAATTTGTAAATATGTTACTATCTCATGGGATCAAGCCTATTCTCGTATTTGATGGATGT
  ACTTTACCTTCTAAAAAGGAAGTAGAGAGATCTAGAAGAGAAAGACGACAAGCCAATCTT
  CTTAAGGGAAAGCAACTTCTTCGTGAGGGGAAAGTCTCGGAAGCTCGAGAGTGTTTCACC
  CGGTCTATCAATATCACACATGCCATGGCCCACAAAGTAATTAAAGCTGCCCGGTCTCAG
  GGGGTAGATTGCCTCGTGGCTCCCTATGAAGCTGATGCGCAGTTGGCCTATCTTAACAAA
  GCGGGAATTGTGCAAGCCATAATTACAGAGGACTCGGATCTCCTAGCTTTTGGCTGTAAA
  AAGGTAATTTTAAAGATGGACCAGTTTGGAAATGGACTTGAAATTGATCAAGCTCGGCTA
  GGAATGTGCAGACAGCTTGGGGATGTATTCACGGAAGAGAAGTTTCGTTACATGTGTATT
  CTTTCAGGTTGTGACTACCTGTCATCACTGCGTGGGATTGGATTAGCAAAGGCATGCAAA
  GTCCTAAGACTAGCCAATAATCCAGATATAGTAAAGGTTATCAAGAAAATTGGACATTAT
  CTCAAGATGAATATCACGGTACCAGAGGATTACATCAACGGGTTTATTCGGGCCAACAAT
  ACCTTCCTCTATCAGCTAGTTTTTGATCCCATCAAAAGGAAACTTATTCCTCTGAACGCC
  TATGAAGATGATGTTGATCCTGAAACACTAAGCTACGCTGGGCAATATGTTGATGATTCC
  ATAGCTCTTCAAATAGCACTTGGAAATAAAGATATAAATACTTTTGAACAGATCGATGAC
  TACAATCCAGACACTGCTATGCCTGCCCATTCAAGAAGTCATAGTTGGGATGACAAAACA
  TGTCAAAAGTCAGCTAATGTTAGCAGCATTTGGCATAGGAATTACTCTCCCAGACCAGAG
  TCGGGTACTGTTTCAGATGCCCCACAATTGAAGGAAAATCCAAGTACTGTGGGAGTGGAA
  CGAGTGATTAGTACTAAAGGGTTAAATCTCCCAAGGAAATCATCCATTGTGAAAAGACCA
  AGAAGTGCAGAGCTGTCAGAAGATGACCTGTTGAGTCAGTATTCTCTTTCATTTACGAAG
  AAGACCAAGAAAAATAGCTCTGAAGGCAATAAATCATTGAGCTTTTCTGAAGTGTTTGTG
  CCTGACCTGGTAAATGGACCTACTAACAAAAAGAGTGTAAGCACTCCACCTAGGACGAGA
  AATAAATTTGCAACATTTTTACAAAGGAAAAATGAAGAAAGTGGTGCAGTTGTGGTTCCA
  GGGACCAGAAGCAGGTTTTTTTGCAGTTCAGATTCTACTGACTGTGTATCAAACAAAGTG
  AGCATCCAGCCTCTGGATGAAACTGCTGTCACAGATAAAGAGAACAATCTGCATGAATCA
  GAGTATGGAGACCAAGAAGGCAAGAGACTGGTTGACACAGATGTAGCACGTAATTCAAGT
  GATGACATTCCGAATAATCATATTCCAGGTGATCATATTCCAGACAAGGCAACAGTGTTT
  ACAGATGAAGAGTCCTACTCTTTTGAGAGCAGCAAATTTACAAGGACCATTTCACCACCC
  ACTTTGGGAACACTAAGAAGTTGTTTTAGTTGGTCTGGAGGTCTTGGAGATTTTTCAAGA
  ACGCCGAGCCCCTCTCCAAGCACAGCATTGCAGCAGTTCCGAAGAAAGAGCGATTCCCCC
  ACCTCTTTGCCTGAGAATAATATGTCTGATGTGTCGCAGTTAAAGAGCGAGGAGTCCAGT
  GACGATGAGTCTCATCCCTTACGAGAAGAGGCATGTTCTTCACAGTCCCAGGAAAGTGGA
  GAATTCTCACTGCAGAGTTCAAATGCATCAAAGCTTTCTCAGTGCTCTAGTAAGGACTCT
  GATTCAGAGGAATCTGATTGCAATATTAAGTTACTTGACAGTCAAAGTGACCAGACCTCC
  AAGCTACGTTTATCTCATTTCTCAAAAAAAGACACACCTCTAAGGAACAAGGTTCCTGGG
  CTATATAAGTCCAGTTCTGCAGACTCTCTTTCTACAACCAAGATCAAACCTCTAGGACCT
  GCCAGAGCCAGTGGGCTGAGCAAGAAGCCGGCAAGCATCCAGAAGAGAAAGCATCATAAT
  GCCGAGAACAAGCCGGGGTTACAGATCAAACTCAATGAGCTCTGGAAAAACTTTGGATTT
  AAAAAATTCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_003686
• ORF Size: 2412 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003686.3, NP_003677.3
• RefSeq Size: 3138
• RefSeq ORF: 2412
• Locus ID: 9156
• Domains: HhH2, XPG_N, XPG_I
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Mismatch repair
• Gene Summary: This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) uses an alternate splice site in the 3' end of the coding region, resulting in a frameshift and use of an upstream stop codon, as compared to variant 1. It encodes isoform a, which is 43 aa shorter than isoform b.