MYOM1 (NM_003803) Human Untagged Clone

CAT#: SC303380

MYOM1 (untagged)-Human myomesin 1, 185kDa (MYOM1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MYOM1
• Synonyms: SKELEMIN
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003803, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTTTGCCTTTTTATCAGAGGTGCCACCAGCACTATGATCTCAGCTACCGCAACAAGGACGTGCGCA
  GCACCGTGAGTCACTACCAGCGGGAGAAGAAACGCTCCGCCGTCTACACCCAGGGCTCCACGGCCTACAG
  CAGCCGCTCCTCCGCCGCGCACCGCCGGGAGTCCGAGGCCTTCCGTCGGGCGTCCGCCTCCTCCTCCCAG
  CAGCAGGCCTCGCAGCACGCCCTGAGCTCTGAAGTCAGTCGGAAGGCAGCCTCAGCCTACGATTATGGCT
  CCTCCCATGGACTTACAGATTCCAGTCTGCTGTTAGATGATTATTCATCCAAGTTGAGCCCCAAACCAAA
  GAGAGCCAAGCACAGCCTACTGTCTGGAGAAGAGAAAGAAAATTTGCCCAGTGACTACATGGTACCCATT
  TTCTCAGGACGTCAAAAGCATGTCAGTGGAATTACTGATACGGAAGAAGAAAGAATTAAAGAAGCTGCTG
  CTTATATAGCCCAGAGGAATCTTCTTGCTAGTGAGGAAGGAATCACAACATCTAAACAGTCCACGGCATC
  CAAGCAGACCACGGCATCTAAGCAGTCCACGGCATCCAAGCAGTCCACAGCATCCAAGCAGTCCACGGCA
  TCCAGGCAGTCCACGGCATCCAGGCAGTCTGTGGTTTCCAAACAGGCCACATCCGCTCTTCAACAGGAAG
  AAACTTCTGAAAAGAAGTCAAGGAAAGTTGTGATTCGAGAAAAGGCAGAACGCCTGTCCCTGAGGAAAAC
  ATTAGAAGAAACCGAGACATATCATGCCAAGCTGAATGAAGACCATCTTCTCCATGCTCCTGAGTTTATC
  ATTAAACCTCGCTCCCACACGGTTTGGGAGAAGGAGAATGTAAAATTGCATTGCTCCATAGCAGGCTGGC
  CAGAACCTCGTGTCACGTGGTATAAAAACCAGGTGCCAATAAATGTCCATGCAAACCCTGGAAAGTATAT
  TATTGAGAGTCGATATGGGATGCACACTCTGGAGATTAATGGATGTGATTTTGAAGATACAGCTCAGTAC
  CGGGCCTCGGCGATGAATGTTAAAGGAGAGCTTTCGGCATATGCTTCAGTTGTGGTAAAAAGGTATAAGG
  GAGAGTTTGATGAGACTCGCTTCCACGCTGGGGCTTCCACCATGCCCCTCAGCTTTGGTGTGACCCCATA
  TGGTTATGCATCCCGGTTTGAGATCCACTTTGATGACAAATTTGATGTGTCTTTTGGGAGAGAGGGAGAG
  ACAATGAGTCTAGGCTGTCGTGTTGTCATCACTCCTGAAATTAAACATTTCCAGCCAGAGATCCAGTGGT
  ACAGAAACGGAGTACCTCTTTCTCCATCAAAATGGGTGCAAACACTTTGGAGTGGAGAGCGGGCAACGCT
  GACATTTTCCCATCTCAACAAAGAAGATGAAGGCCTCTATACAATCCGTGTACGGATGGGAGAATATTAT
  GAACAATATAGTGCTTATGTCTTTGTTCGAGATGCTGATGCAGAGATTGAAGGAGCCCCAGCTGCTCCCT
  TGGATGTGAAGTGCTTGGAGGCCAACAAAGATTATATCATCATCTCCTGGAAACAGCCAGCTGTCGATGG
  AGGGAGTCCTATTCTCGGATATTTTATTGATAAGTGTGAGGTGGGCACAGATAGCTGGTCGCAGTGCAAT
  GACACACCTGTGAAGTTTGCTCGTTTTCCTGTCACTGGATTGATCGAAGGTCGTTCCTATATCTTCCGAG
  TTCGAGCTGTGAATAAAATGGGAATAGGTTTCCCATCTCGAGTTTCCGAGCCCGTGGCTGCTCTGGATCC
  GGCTGAGAAAGCTAGACTTAAAAGTCGCCCCTCAGCACCCTGGACTGGACAGATCATTGTTACTGAAGAG
  GAACCTTCAGAGGGTATTGTGCCTGGCCCCCCGACAGACCTCTCTGTCACTGAGGCCACCCGGAGCTATG
  TGGTGCTCAGCTGGAAGCCCCCTGGCCAGCGTGGTCATGAGGGCATTATGTACTTTGTGGAAAAGTGTGA
  GGCAGGAACAGAAAACTGGCAGCGAGTGAACACGGAGCTCCCTGTGAAGTCTCCCCGCTTTGCTCTGTTT
  GACTTGGCCGAGGGGAAATCCTACTGTTTCCGTGTCCGCTGTTCTAATTCTGCAGGAGTTGGTGAGCCCT
  CAGAGGCAACGGAGGTGACTGTGGTAGGGGACAAACTTGATATCCCCAAGGCTCCTGGCAAAATCATCCC
  AAGCAGAAACACAGACACCTCAGTGGTAGTTTCGTGGGAGGAGTCCAAAGATGCCAAAGAGCTGGTCGGG
  TACTACATAGAGGCGAGCGTTGCTGGCTCTGGCAAGTGGGAGCCCTGTAACAACAACCCCGTGAAGGGCT
  CACGATTCACTTGTCATGGATTAGTGACTGGTCAGAGTTATATTTTCCGGGTCAGAGCAGTCAATGCAGC
  TGGACTTAGTGAATATTCCCAGGATTCAGAAGCTATTGAAGTCAAAGCTGCTATTGGGGGAGGAGTGTCT
  CCAGATGTGTGTCCCGCACTGAGCGATGAGCCTGGTGGACTAACCGCCTCCAGGGGGCGCGTGCATGAAG
  CCTCCCCGCCAACCTTCCAGAAAGATGCTTTGCTTGGCAGCAAACCTAACAAACCTTCACTACCCAGTAG
  CTCTCAAAACCTGGGCCAAACAGAAGTGAGTAAAGTAAGTGAAACAGTTCAGGAAGAGCTTACCCCGCCA
  CCACAGAAAGCGGCTCCTCAGGGGAAAAGTAAGTCTGACCCCCTGAAAAAGAAGACAGACAGAGCACCAC
  CATCTCCACCCTGTGATATCACCTGTCTTGAAAGTTTTCGTGACTCAATGGTTCTTGGATGGAAGCAACC
  AGATAAGATTGGAGGGGCAGAAATTACTGGCTATTATGTGAACTATCGCGAGGTCATTGATGGGGTACCA
  GGAAAATGGAGAGAAGCCAATGTCAAGGCTGTCAGTGAGGAGGCATACAAGATTAGCAACTTGAAGGAAA
  ACATGGTGTATCAGTTCCAAGTGGCAGCCATGAACATGGCTGGGCTGGGCGCGCCCTCCGCAGTAAGCGA
  ATGCTTCAAATGTGAAGAGTGGACCATCGCCGTCCCAGGACCACCGCACAGTCTCAAGTGTAGTGAAGTC
  AGGAAAGACTCACTGGTTCTCCAGTGGAAGCCGCCAGTCCACTCCGGGCGGACTCCGGTCACTGGTTACT
  TCGTGGACTTGAAGGAGGCCAAGGCCAAAGAAGACCAGTGGCGAGGGCTCAATGAGGCGGCTATTAAAAA
  CGTATACCTGAAGGTTCGAGGCCTCAAGGAGGGCGTCAGCTACGTGTTCCGTGTTCGAGCCATAAACCAG
  GCGGGAGTTGGGAAGCCATCTGACCTTGCTGGCCCTGTTGTGGCAGAGACCCGTCCAGGAACCAAAGAGG
  TTGTTGTAAATGTGGATGATGATGGAGTCATTTCATTGAACTTCGAGTGTGATAAGATGACTCCAAAGTC
  CGAGTTCTCCTGGTCCAAAGATTATGTATCCACTGAGGACTCTCCACGATTGGAAGTCGAAAGCAAGGGC
  AACAAGACGAAAATGACCTTCAAAGACCTTGGGATGGATGACTTGGGTATTTACTCTTGCGATGTAACAG
  ACACTGATGGAATAGCATCAAGCTACTTAATAGATGAGGAAGAATTGAAACGTTTACTTGCTCTCAGCCA
  TGAACACAAGTTCCCAACTGTCCCAGTTAAATCAGAGTTGGCAGTTGAAATTTTGGAGAAAGGCCAGGTC
  CGGTTTTGGATGCAGGCTGAGAAACTGTCTGGCAATGCCAAAGTCAACTACATATTTAACGAGAAGGAAA
  TTTTTGAAGGCCCGAAATATAAAATGCATATTGACCGAAACACTGGCATCATCGAAATGTTCATGGAAAA
  GCTACAGGATGAGGATGAGGGAACGTACACTTTCCAGCTTCAAGATGGAAAAGCAACTAACCATTCTACT
  GTTGTTCTCGTTGGAGATGTTTTCAAAAAGCTCCAGAAAGAAGCTGAATTCCAGCGGCAAGAATGGATCA
  GGAAACAAGGTCCTCACTTTGTTGAGTATTTGAGCTGGGAAGTGACTGGTGAATGTAATGTACTATTGAA
  ATGCAAGGTGGCAAATATTAAGAAGGAGACTCATATTGTGTGGTACAAAGATGAGAGGGAGATATCAGTG
  GATGAAAAGCATGACTTTAAGGATGGTATATGTACCCTGCTTATAACAGAGTTTTCCAAGAAAGATGCTG
  GGATTTATGAAGTTATCCTGAAAGATGACCGAGGAAAAGATAAGAGCAGACTGAAGCTTGTGGATGAAGC
  CTTTAAGGAACTGATGATGGAAGTATGCAAAAAAATAGCTTTGTCTGCTACAGACCTGAAAATCCAGAGC
  ACAGCCGAGGGCATCCAACTGTACTCTTTTGTAACTTACTATGTGGAGGATTTGAAAGTTAACTGGTCCC
  ACAATGGGTCCGCCATTAGGTACTCAGACAGAGTTAAGACCGGGGTCACTGGAGAGCAGATCTGGCTACA
  AATCAACGAGCCCACCCCGAATGACAAAGGGAAGTATGTCATGGAGCTCTTTGATGGCAAAACTGGACAT
  CAGAAGACAGTGGATCTCTCTGGACAAGCATACGATGAGGCCTATGCTGAATTCCAGAGGTTGAAACAAG
  CTGCCATTGCCGAGAAAAATCGTGCCCGGGTGTTGGGAGGTCTCCCAGACGTGGTCACCATCCAGGAGGG
  GAAGGCCCTTAATCTCACTTGCAACGTGTGGGGAGACCCGCCTCCGGAGGTGTCGTGGTTGAAGAACGAG
  AAGGCCCTGGCCTCAGACGACCACTGCAACCTCAAGTTCGAGGCTGGGAGGACCGCGTACTTCACCATCA
  ACGGCGTGAGCACCGCTGACTCGGGCAAATACGGGCTGGTTGTGAAGAACAAGTATGGCTCGGAGACCAG
  CGACTTCACCGTCAGCGTGTTCATCCCAGAGGAGGAGGCGAGGATGGCCGCCTTGGAGTCCCTGAAAGGT
  GGCAAGAAGGCCAAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_003803
• ORF Size: 5058 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003803.3, NP_003794.3
• RefSeq Size: 5848
• RefSeq ORF: 5058
• Locus ID: 8736
• Gene Summary: The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer isoform (a).