ITGB1BP2 (NM_012278) Human Untagged Clone

CAT#: SC303950

ITGB1BP2 (untagged)-Human integrin beta 1 binding protein (melusin) 2 (ITGB1BP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITGB1BP2
• Synonyms: CHORDC3; ITGB1BP; MELUSIN; MSTP015
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012278, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTCTACTCTGTCGTAACAAAGGCTGTGGGCAGCACTTTGACCCTAATACCAACCTTCCTGATTCCT
  GTTGCCATCACCCTGGGGTCCCAATCTTCCATGATGCACTTAAGGGTTGGTCCTGCTGCCGAAAGCGAAC
  TGTAGATTTCTCTGAGTTCTTAAACATCAAGGGCTGTACTATGGGACCACACTGTGCTGAGAAGCTTCCT
  GAGGCCCCTCAACCTGAAGGCCCTGCTACAAGCAGTTCACTTCAGGAGCAAAAACCTCTGAATGTGATTC
  CAAAGTCAGCAGAGACCTTGCGCCGGGAGAGGCCCAAGTCAGAGTTGCCTCTGAAGCTGCTGCCGCTAAA
  TATATCCCAAGCCCTGGAAATGGCATTGGAACAGAAGGAATTAGACCAGGAACCTGGGGCAGGACTTGAC
  AGTCTGATCCGGACTGGTTCCAGCTGCCAGAACCCAGGATGTGATGCTGTTTACCAAGGCCCTGAGAGTG
  ATGCTACTCCATGTACCTACCACCCAGGAGCACCCCGATTCCATGAGGGGATGAAGTCTTGGAGCTGTTG
  TGGCATCCAGACCCTGGATTTTGGGGCATTCTTGGCACAACCAGGGTGCAGAGTCGGTAGACATGACTGG
  GGGAAGCAGCTCCCAGCATCTTGCCGCCATGATTGGCACCAGACAGATTCCTTAGTAGTGGTGACTGTAT
  ATGGCCAGATTCCACTTCCTGCGTTTAACTGGGTGAAGGCCAGTCAAACTGAGCTTCATGTCCACATTGT
  CTTTGATGGTAACCGTGTGTTCCAAGCACAGATGAAGCTCTGGGGGGTCATAAACGTGGAGCAGAGCTCT
  GTCTTCTTGATGCCATCTCGGGTTGAAATCTCCCTGGTCAAGGCTGACCCAGGATCCTGGGCCCAGCTGG
  AGCACCCTGATGCACTAGCTAAGAAGGCTAGGGCAGGGGTTGTGTTAGAGATGGATGAGGAAGAATCTGA
  CGATTCAGATGATGATCTGAGCTGGACAGAGGAGGAGGAAGAGGAGGAAGCAATGGGGGAATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_012278
• ORF Size: 1044 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012278.2, NP_036410.1
• RefSeq Size: 1292
• RefSeq ORF: 1044
• Locus ID: 26548
• Gene Summary: This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).