PCDHGA8 (NM_014004) Human Untagged Clone

CAT#: SC304031

PCDHGA8 (untagged)-Human protocadherin gamma subfamily A, 8 (PCDHGA8), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGA8
• Synonyms: PCDH-GAMMA-A8
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014004, the custom clone sequence may differ by one or more nucleotides
  ATGGCCGCTCCACAGAGTCGCCCCAGACGCGGCGAGCTGATCCTGCTGTGCGCGCTGCTG
  GGAACGCTGTGGGAAATCGGGAGGGGACAGATTCGCTACTCTGTGCCAGAAGAGACGGAC
  AAAGGCTCCTTCGTGGGTAATATCTCCAAGGACCTGGGGCTGGACCCCCGGAAGCTGGCG
  AAGCACGGAGTCCGTATCGTCTCCAGAGGTAGGACGCAGCTCTTTGCTCTGAACCCGCGC
  AGCGGCAGCTTGATCACCGCGGGCAGGATAGATCGGGAGGAGCTCTGCGCTCAGAGCCCG
  CGGTGTCTGATAAATATTAACACCCTGGTTGAGGATAAAGGAAAACTCTTTGGGGTAGAA
  ATAGAAATAATTGATATTAACGATAATAACCCAAAATTCCAGGTCGAAGATCTAGAAGTA
  AAAATTAACGAAATCGCGGTTCCTGGAGCACGTTATCCACTCCCAGAAGCTGTTGACCCG
  GATGTGGGCGTGAACTCCCTCCAGAGCTACCAGCTCAGCCCCAATCACCACTTCTCCCTG
  GACGTGCAGACTGGAGACAATGGAGCCATAAACCCAGAGCTGGTGCTGGAGCGCGCCCTG
  GACAGGGAGGAAGAGGCTGCTCACCACCTGGTCCTCACGGCCTCGGATGGCGGCAAGCCG
  CCTCGCTCTAGCACAGTGCGCATCCACGTGACAGTGTTGGATACAAATGACAATGCCCCG
  GTTTTTCCTCACCCGATTTACCGAGTGAAAGTCCTTGAGAACATGCCCCCAGGCACGCGG
  CTGCTTACTGTAACAGCCAGCGACCCGGATGAGGGAATCAACGGAAAAGTGGCATACAAA
  TTCCGGAAAATTAATGAAAAACAAACTCCGTTATTCCAGCTTAATGAAAATACTGGGGAA
  ATATCAATAGCAAAAAGTCTAGATTATGAAGAATGTTCATTTTATGAAATGGAAATACAA
  GCCGAAGATGTGGGGGCACTTCTGGGGAGGACCAAATTGCTCATTTCGGTGGAAGATGTA
  AATGACAATAGACCAGAAGTGATCATTACGTCTTTGTTTAGCCCAGTGTTAGAAAATTCT
  CTTCCCGGGACAGTAATTGCCTTCTTGAGTGTGCATGACCAAGACTCTGGAAAGAATGGT
  CAAGTTGTCTGTTACACACGTGATAATTTACCTTTTAAATTAGAAAAGTCAATAGGTAAT
  TATTATAGATTAGTGACAAGGAAATATTTGGACCGAGAAAATGTCTCTATCTACAATATC
  ACAGTGATGGCCTCAGATCTAGGAACACCACCTCTGTCCACTGAAACTCAAATCGCTCTG
  CACGTGGCAGACATTAACGACAACCCTCCTACTTTCCCTCATGCCTCCTACTCAGCGTAT
  ATCCTAGAGAACAACCTGAGAGGAGCCTCCATCTTTTCCTTGACTGCACACGACCCCGAC
  AGCCAGGAGAATGCCCAGGTCACTTACTCTGTGACCGAGGACACGCTGCAGGGGGCGCCC
  CTGTCCTCGTATATCTCCATCAACTCTGACACCGGTGTCCTGTATGCGCTGCAATCTTTC
  GACTATGAGCAGATCCGAGACCTGCAGCTACTGGTAACAGCCAGCGACAGCGGGGACCCG
  CCCCTCAGCAGCAACATGTCACTGAGCCTGTTCGTGCTGGACCAGAATGACAACGCGCCC
  GAGATCCTGTACCCCGCCCTCCCCACAGACGGTTCCACTGGCGTGGAGCTGGCGCCCCGC
  TCCGCAGAGCGTGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGAGACTCGGGCCAG
  AACGCCTGGCTGTCCTACCGCCTGCTCAAGGCCAGCGAGCCGGGACTCTTCTCGGTGGGT
  CTGCACACGGGCGAGGTGCGCACGGCGCGAGCCCTGCTGGACAGAGATGCGCTCAAGCAG
  AGCCTCGTGGTGGCCGTCCAGGACCATGGCCAGCCCCCTCTCTCCGCCACTGTCACGCTC
  ACCGTAGCCGTGGCTGACAGCATCCCCGAAGTCCTGACCGAGTTGGGCAGTCTGAAGCCT
  TCGGTCGACCCGAACGATTCGAGCCTTACACTCTATCTCGTGGTGGCAGTGGCTGCCATC
  TCCTGTGTCTTCCTCGCCTTTGTCGCTGTGCTTCTGGGGCTCAGGCTGAGGCGCTGGCAC
  AAGTCACGCCTGCTCCAGGATTCCGGTGGCAGATTGGTAGGCGTGCCTGCCTCACATTTT
  GTGGGTGTTGAGGAGGTACAGGCTTTCCTGCAGACCTATTCCCAGGAAGTCTCCCTCACC
  GCCGACTCGCGGAAGAGTCACCTGATCTTTCCCCAGCCCAACTACGCAGACATGCTCATC
  AGTCAGGAGGGCTGTGAGAAAAATGATTCTTTGTTAACATCCGTAGATTTTCATGAATAT
  AAGAATGAAGCTGATCATGGTCAGGTGAGTTTAGTTCTTTGCTTGCTTTTAATTTCCAGA
  TGA
  
• Restriction Sites: Please inquire
• ACCN: NM_014004
• ORF Size: 2463 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014004.2, NP_054723.1
• RefSeq Size: 3488
• RefSeq ORF: 2463
• Locus ID: 9708
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes the shorter isoform (2).