Zonula occludens protein 3 (TJP3) (NM_014428) Human Untagged Clone

CAT#: SC304103

TJP3 (untagged)-Human tight junction protein 3 (zona occludens 3) (TJP3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TJP3
• Synonyms: ZO-3; ZO3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014428 edited
  ATGAACCTGTGTGGCCTCATGCCCATCTTCCCCGCTCCCCTCGACCAGGTGGCTGACATG
  GAGGAGCTGACCATCTGGGAACAGCACACGGCCACACTGTCCAAGGACCCCCACCGGGGC
  TTTGGCATTGCGATCTCTGGAGGCCGAGACCGGCCCGGTGGATCCATGGTTGTATCTGAC
  GTGGTACCTGGAGGGCCGGCGGAGGGCAGGCTACAGACAGGCGACCACATTGTCATGGTG
  AACGGGGTTTCCATGGAGAATGCCACCTCCGCGTTTGCCATTCAGATACTCAAGACCTGC
  ACCAAGATGGCCAACATCACAGTGAAACGTCCCCGGAGGATCCACCTGCCCGCCACCAAA
  GCCAGCCCCTCCAGCCCAGGGCGCCAGGACTCGGATGAAGACGATGGGCCCCAGCGGGTG
  GAGGAGGTGGACCAGGGCCGGGGCTATGACGGCGACTCATCCAGTGGCTCCGGCCGCTCC
  TGGGACGAGCGCTCCCGCCGGCCGAGGCCTGGTCGCCGGGGCCGGGCCGGCAGCCATGGG
  CGTAGGAGCCCAGGTGGTGGCTCTGAGGCCAACGGGCTGGCCCTGGTGTCCGGCTTTAAG
  CGGCTGCCACGGCAGGACGTGCAGATGAAGCCTGTGAAGTCAGTGCTGGTGAAGAGGAGA
  GACAGCGAAGAGTTTGGCGTCAAGCTGGGCAGTCAGATCTTCATCAAGCACATTACAGAT
  TCAGGCCTGGCTGCCCGGCACCGTGGGCTGCAGGAAGGAGATCTCATTCTACAGATCAAC
  GGGGTGTCTAGCCAGAACCTGTCACTGAACGACACCCGGCGACTGATTGAGAAGTCAGAA
  GGGAAGCTAAGCCTGCTGGTGCTGAGAGATCGTGGGCAGTTCCTGGTGAACATTCCGCCT
  GCTGTCAGTGACAGCGACAGCTCGCCATTGGAGGAAGGCGTGACCATGGCTGATGAGATG
  TCCTCTCCCCCTGCAGACATCTCGGACCTCGCCTCGGAGCTATCGCAGGCACCACCATCC
  CACATCCCACCACCACCCCGGCATGCTCAGCGGAGCCCCGAGGCCAGCCAGACCGACTCT
  CCCGTGGAGAGTCCCCGGCTTCGGCGGGAAAGTTCAGTAGATTCCAGAACCATCTCGGAA
  CCAGATGAGCAACGGTCAGAGTTGCCCAGGGAAAGCAGCTATGACATCTACAGAGTGCCC
  AGCAGTCAGAGCATGGAGGATCGTGGGTACAGCCCCGACACGCGTGTGGTCCGCTTCCTC
  AAGGGCAAGAGCATCGGGCTGCGGCTGGCAGGGGGCAATGACGTGGGCATCTTCGTGTCC
  GGGGTGCAGGCGGGCAGCCCGGCCGACGGGCAGGGCATCCAGGAGGGAGATCAGATTCTG
  CAGGTGAATGACGTGCCATTCCAGAACCTGACACGGGAGGAGGCAGTGCAGTTCCTGCTG
  GGGCTGCCACCAGGCGAGGAGATGGAGCTGGTGACGCAGCGGAAGCAGGACATTTTCTGG
  AAAATGGTGCAGTCCCGCGTGGGTGACTCCTTCTACATCCGCACTCACTTTGAGCTGGAG
  CCCAGTCCGCCGTCTGGCCTGGGCTTCACCCGTGGCGACGTCTTCCACGTGCTGGACACG
  CTGCACCCCGGCCCCGGGCAGAGCCACGCACGAGGAGGCCACTGGCTGGCGGTGCGCATG
  GGTCGTGACCTGCGGGAGCAAGAGCGGGGCATCATTCCCAACCAGAGCAGGGCGGAGCAG
  CTGGCCAGCCTGGAAGCTGCCCAGAGGGCCGTGGGAGTCGGGCCCGGCTCCTCCGCGGGC
  TCCAATGCTCGGGCCGAGTTCTGGCGGCTGCGGGGTCTGCGTCGAGGAGCCAAGAAGACC
  ACTCAGCGGAGCCGTGAGGACCTCTCAGCTCTGACCCGACAGGGCCGCTACCCGCCCTAC
  GAACGAGTGGTGTTGCGAGAAGCCAGTTTCAAGCGCCCGGTAGTGATCCTGGGACCCGTG
  GCCGACATTGCTATGCAGAAGTTGACTGCTGAGATGCCTGACCAGTTTGAAATCGCAGAG
  ACTGTGTCCAGGACCGACAGCCCCTCCAAGATCATCAAACTAGACACCGTGCGGGTGATT
  GCAGAAAAAGACAAGCATGCGCTCCTGGATGTGACCCCCTCCGCCATCGAGCGCCTCAAC
  TATGTGCAGTACTACCCCATTGTGGTCTTCTTCATCCCCGAGAGCCGGCCGGCCCTCAAG
  GCACTGCGCCAGTGGCTGGCGCCTGCCTCCCGCCGCAGCACCCGTCGCCTCTACGCACAA
  GCCCAGAAGCTGCGAAAACACAGCAGCCACCTCTTCACAGCCACCATCCCTCTGAATGGC
  ACGAGTGACACCTGGTACCAGGAGCTCAAGGCCATCATTCGAGAGCAGCAGACGCGGCCC
  ATCTGGACGGCGGAAGATCAGCTGGATGGCTCCTTGGAGGACAACCTAGACCTCCCTCAC
  CACGGCCTGGCCGACAGCTCCGCTGACCTCAGCTGCGACAGCCGCGTTAACAGCGACTAC
  GAGACGGACGGCGAGGGCGGCGCGTACACGGATGGCGAGGGCTACACAGACGGCGAGGGG
  GGGCCCTACACGGATGTGGATGATGAGCCCCCGGCTCCAGCCCTGGCCCGGTCCTCGGAG
  CCCGTGCAGGCAGATGAGTCCCAGAGCCCGAGGGATCGTGGGAGAATCTCGGCTCATCAG
  GGGGCCCAGGTGGACAGCCGCCACCCCCAGGGACAGTGGCGACAGGACAGCATGCGAACC
  TATGAACGGGAAGCCCTGAAGAAAAAGTTTACGCGAGTCCATGATGCGGAGTCCTCCGAT
  GAAGACGGCTATGACTGGGGTCCGGCCACTGACCTGTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_014428
• ORF Size: 2859 bp
• Insert Size: 2900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain 3 SNPs compared with NM_014428.1.

Reference Data

• RefSeq: NM_014428.1, NP_055243.1
• RefSeq Size: 2859
• RefSeq ORF: 2859
• Locus ID: 27134
• Protein Pathways: Tight junction
• Gene Summary: The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]