SCRIBBLE (SCRIB) (NM_015356) Human Untagged Clone

CAT#: SC304298

SCRIB (untagged)-Human scribbled homolog (Drosophila) (SCRIB), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCRIB
• Synonyms: CRIB1; SCRB1; SCRIB1; Vartul
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015356, the custom clone sequence may differ by one or more nucleotides
  ATGCTCAAGTGCATCCCGCTGTGGCGCTGCAACCGGCACGTGGAGTCGGTGGACAAGCGG
  CACTGTTCGCTGCAGGCCGTGCCGGAGGAGATCTACCGCTACAGCCGCAGCCTGGAGGAG
  CTGCTGCTCGACGCCAACCAGCTGCGCGAGCTGCCCAAGCCTTTTTTCCGGCTGCTGAAC
  TTGCGCAAGCTGGGCCTGAGCGACAACGAGATCCAGCGGTTGCCTCCCGAGGTGGCCAAC
  TTCATGCAGCTGGTGGAGCTGGACGTGTCCCGGAACGATATCCCTGAGATCCCGGAGAGC
  ATCAAGTTCTGCAAGGCTCTGGAGATCGCGGACTTCAGCGGGAACCCCCTCTCCAGGCTC
  CCTGATGGCTTCACTCAGCTGCGCAGCCTGGCTCACCTGGCCCTGAATGATGTGTCTCTG
  CAGGCACTGCCCGGGGACGTGGGCAACCTCGCCAACCTGGTGACCCTGGAGCTCCGGGAG
  AACCTGCTCAAGTCCCTGCCAGCGTCCCTGTCATTTCTGGTCAAGCTGGAACAGCTGGAT
  CTGGGAGGCAACGATCTGGAAGTGCTGCCAGACACTCTGGGGGCTCTGCCCAATCTTCGG
  GAGCTGTGGCTTGACCGGAACCAGCTGTCAGCACTGCCCCCGGAGCTCGGGAACCTGCGG
  CGCCTGGTGTGCCTGGACGTGTCGGAAAACCGGCTGGAGGAGCTGCCTGCTGAGCTCGGC
  GGGCTGGTGCTGCTCACTGACCTGCTGCTGTCCCAGAACCTGCTGCGGAGGCTGCCCGAC
  GGCATCGGTCAGCTGAAGCAGCTATCCATCCTAAAGGTAGACCAGAATCGGCTGTGCGAG
  GTGACTGAGGCCATCGGGGACTGTGAGAACCTCTCTGAGCTGATCCTCACGGAGAACCTG
  CTGATGGCCCTGCCCCGCTCCCTGGGAAAGCTGACTAAGCTGACCAACCTCAACGTGGAC
  CGGAACCACCTCGAGGCGCTGCCGCCCGAGATCGGGGGCTGTGTGGCACTCAGCGTCCTC
  TCCTTGAGGGACAACCGCCTGGCCGTCCTGCCACCAGAGCTGGCCCACACGACAGAGCTG
  CACGTGCTGGACGTGGCGGGGAACCGCCTGCAGAGTCTGCCGTTCGCGCTCACCCACCTC
  AATCTCAAGGCCCTGTGGCTGGCAGAGAACCAGGCGCAGCCCATGCTCCGGTTCCAGACG
  GAGGATGATGCCCGGACCGGCGAGAAGGTGCTCACCTGCTACTTGCTGCCCCAGCAGCCC
  CCACTCAGCCTCGAGGATGCTGGGCAGCAGGGGAGCCTCTCGGAGACCTGGAGCGATGCC
  CCGCCGAGCCGCGTCAGCGTCATCCAGTTCCTGGAGGCCCCCATAGGTGATGAGGACGCT
  GAGGAAGCTGCAGCTGAGAAGCGGGGCCTACAGCGCCGGGCCACACCTCACCCCAGCGAG
  CTCAAGGTGATGAAGAGGAGCATCGAGGGGCGGCGGAGCGAGGCCTGCCCTTGCCAGCCA
  GACTCTGGGTCGCCCTTGCCTGCAGAGGAGGAGAAGCGGCTGAGTGCCGAGTCTGGCCTG
  AGTGAAGACTCTCGCCCATCTGCCAGCACAGTCTCTGAGGCTGAGCCCGAGGGCCCGTCG
  GCTGAGGCACAGGGTGGGAGCCAGCAGGAAGCCACGACTGCTGGCGGGGAGGAAGACGCC
  GAAGAGGACTACCAGGAGCCCACGGTGCATTTCGCAGAGGACGCACTGCTGCCCGGGGAT
  GACAGGGAGATCGAGGAGGGGCAGCCTGAGGCCCCCTGGACCCTGCCAGGCGGGAGGCAG
  CGGCTCATCCGCAAGGACACACCTCACTACAAAAAGCACTTCAAGATCTCCAAGCTGCCC
  CAGCCCGAGGCCGTTGTGGCTCTGCTGCAGGGCATGCAGCCTGATGGGGAGGGCCCTGTG
  GCTCCCGGGGGCTGGCACAATGGCCCCCACGCACCCTGGGCTCCTCGGGCCCAGAAGGAG
  GAGGAGGAGGAGGAAGAGGGTAGTCCTCAGGAGGAGGAGGAAGAGGAGGAGGAGGAAAAC
  AGGGCTGAAGAGGAAGAGGCCAGCACTGAGGAGGAGGACAAGGAGGGGGCCGTGGTTTCT
  GCGCCCTCTGTCAAGGGAGTGTCGTTTGACCAGGCCAATAACCTGCTGATAGAGCCTGCT
  CGCATTGAGGAGGAAGAGCTGACCCTCACCATCCTGCGGCAGACTGGGGGCCTGGGCATC
  AGCATTGCGGGCGGCAAGGGCTCCACACCCTATAAGGGGGACGACGAGGGCATATTCATC
  TCTCGGGTGTCCGAGGAAGGCCCTGCGGCCCGGGCTGGAGTCCGTGTGGGTGACAAGCTC
  CTGGAGGTGAATGGTGTGGCTCTGCAGGGCGCCGAGCACCACGAGGCCGTGGAGGCGCTC
  CGGGGGGCCGGCACTGCCGTGCAGATGCGAGTGTGGCGGGAGCGCATGGTGGAGCCTGAG
  AACGCGGTCACCATCACGCCGCTGCGGCCCGAGGATGATTACAGCCCCCGAGAGCGGCGG
  GGAGGGGGGCTGCGCCTGCCCCTGCTCCCGCCTGAGAGCCCCGGGCCCCTCCGTCAGCGC
  CACGTGGCCTGCCTGGCACGCAGCGAGAGGGGGCTGGGCTTCAGCATTGCTGGTGGGAAA
  GGCTCCACACCCTACAGGGCTGGTGATGCGGGCATCTTCGTCTCCCGCATTGCCGAGGGC
  GGTGCTGCTCACCGCGCGGGCACACTGCAGGTTGGCGACCGCGTCCTCTCTATTAATGGA
  GTGGACGTGACTGAGGCCAGGCATGACCACGCCGTCTCCCTGCTGACCGCTGCCTCCCCC
  ACCATCGCCCTGCTGTTGGAGCGGGAGGCTGGGGGCCCTCTTCCTCCCAGCCCTCTGCCA
  CATTCCTCACCCCCCACCGCTGCTGTTGCCACCACCAGCATAACCACTGCCACCCCCGGG
  GTGCCTGGGTTGCCGAGCCTGGCCCCCAGCCTGCTGGCTGCCGCGTTGGAAGGGCCATAC
  CCAGTGGAGGAGATCCGTCTGCCAAGAGCTGGGGGCCCTCTGGGGCTTAGTATTGTCGGA
  GGCTCCGACCATTCCAGCCACCCGTTTGGTGTCCAGGAGCCTGGTGTGTTCATCTCCAAG
  GTGCTCCCGCGGGGCCTGGCCGCTCGCAGCGGCCTGCGGGTTGGGGACCGCATCCTGGCA
  GTGAACGGGCAAGACGTGCGGGATGCCACGCACCAAGAAGCAGTCAGTGCCCTGCTCCGG
  CCCTGCCTGGAGCTGTCGCTGCTGGTGCGGAGGGACCCGGCACCCCCGGGCCTACGGGAA
  CTGTGCATCCAGAAGGCACCTGGGGAGAGGCTGGGCATCAGCATCCGCGGGGGTGCCAGG
  GGCCACGCTGGCAACCCCCGCGACCCCACAGACGAGGGCATCTTCATCTCCAAGGTGAGC
  CCCACGGGGGCAGCCGGGCGCGACGGTCGGCTGCGTGTGGGTTTGCGGCTGTTGGAGGTG
  AACCAGCAGAGCCTGCTGGGCCTGACGCACGGCGAGGCGGTGCAGCTGCTCCGCAGTGTG
  GGCGACACCCTCACCGTGCTGGTCTGTGACGGCTTCGAGGCCAGCACCGACGCAGCCCTG
  GAGGTGTCCCCAGGTGTCATTGCCAACCCCTTTGCGGCAGGCATCGGCCACCGGAACAGC
  CTGGAGAGCATCTCTTCCATCGACCGGGAGCTGAGCCCTGAGGGCCCAGGCAAGGAGAAG
  GAGCTGCCTGGACAGACCCTGCACTGGGGGCCCGAGGCCACAGAAGCCGCAGGTCGGGGT
  CTGCAGCCCCTGAAGCTGGACTACCGCGCCCTGGCCGCCGTGCCCAGCGCTGGCAGCGTG
  CAGAGGGTACCGTCTGGAGCAGCTGGAGGGAAGATGGCTGAATCTCCCTGCTCCCCTAGT
  GGCCAGCAGCCGCCCTCCCCGCCTTCTCCGGATGAGCTGCCCGCCAATGTGAAGCAGGCC
  TACAGGGCCTTCGCGGCCGTGCCCACTTCTCACCCGCCTGAGGATGCCCCTGCCCAGCCC
  CCCACGCCTGGGCCTGCAGCCTCCCCGGAGCAGCTGTCCTTCCGGGAGCGGCAGAAGTAC
  TTTGAGCTGGAGGTGCGCGTGCCCCAGGCCGAGGGCCCCCCTAAGCGCGTGTCCCTGGTG
  GGTGCTGACGACCTGCGGAAGATGCAGGAGGAGGAAGCCAGAAAACTACAGCAGAAGAGA
  GCGCAGATGCTGCGGGAGGCGGCAGAGGCTGGGGCCGAAGCGAGGCTCGCCCTGGACGGG
  GAGACGCTGGGCGAGGAGGAACAGGAGGATGAGCAGCCACCCTGGGCCAGCCCGAGCCCC
  ACCTCAAGGCAGAGCCCGGCGTCCCCCCCGCCCCTGGGAGGTGGCGCCCCGGTGCGGACG
  GCCAAAGCTGAACGGCGCCACCAGGAGCGGCTGCGCGTGCAGAGTCCGGAGCCACCGGCA
  CCCGAGCGTGCCCTGTCCCCTGCCGAGCTCCGGGCCCTGGAGGCCGAGAAGCGTGCGCTG
  TGGAGGGCAGCCAGGATGAAGTCATTGGAACAGGACGCTCTCCGAGCACAGATGGTCCTC
  AGCAGGTCCCAGGAAGGCCGGGGCACGCGGGGGCCCCTGGAGCGACTGGCCGAGGCCCCT
  TCCCCTGCGCCCACCCCGTCGCCCACCCCTGTGGAAGACCTCGGCCCCCAGACCAGCACC
  TCCCCGGGACGCCTGTCACCGGACTTTGCTGAGGAGTTGAGGTCCCTGGAACCATCTCCC
  AGCCCTGGCCCGCAGGAGGAGGATGGAGAAGTGGCTCTGGTGCTTCTGGGCAGGCCCTCA
  CCCGGCGCTGTGGGCCCTGAAGATGTGGCACTGTGCAGCAGCCGCCGCCCCGTAAGGCCT
  GGGCGCCGTGGCCTGGGCCCTGTGCCCTCCTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_015356
• ORF Size: 4893 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015356.2, NP_056171.2
• RefSeq Size: 5146
• RefSeq ORF: 4893
• Locus ID: 23513
• Gene Summary: This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.