MYO3A (NM_017433) Human Untagged Clone

CAT#: SC304463

MYO3A (untagged)-Human myosin IIIA (MYO3A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MYO3A
• Synonyms: DFNB30
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017433, the custom clone sequence may differ by one or more nucleotides
  ATGTTTCCATTAATTGGAAAAACAATCATCTTTGATAACTTTCCTGATCCTTCTGATACA
  TGGGAAATCACTGAGACAATTGGCAAAGGAACTTATGGGAAAGTTTTTAAAGTATTGAAT
  AAGAAAAATGGCCAAAAAGCAGCAGTCAAAATTCTTGATCCAATTCACGATATTGACGAA
  GAGATTGAAGCAGAATATAACATCTTAAAAGCACTTTCTGACCACCCTAATGTGGTCAGA
  TTCTATGGGATATACTTTAAGAAGGATAAAGTAAATGGAGACAAGCTGTGGTTGGTTCTT
  GAGCTCTGCAGTGGAGGATCAGTGACTGACCTTGTGAAAGGATTTCTGAAGAGGGGTGAA
  AGAATGAGTGAGCCTCTAATTGCCTATATTTTACATGAAGCACTAATGGGACTTCAACAT
  TTGCATAACAACAAAACTATCCACAGAGATGTGAAAGGCAATAACATTCTATTGACCACG
  GAAGGTGGAGTGAAACTAGTAGATTTTGGTGTGTCTGCACAGCTCACCAGTACCCGGCAC
  CGTCGGAACACATCCGTAGGAACACCGTTTTGGATGGCTCCTGAGGTGATTGCATGTGAA
  CAGCAATTGGATACCACTTATGACGCCAGATGTGACACTTGGTCCCTGGGTATCACGGCC
  ATTGAGCTGGGTGATGGAGATCCTCCACTAGCTGACCTTCATCCCATGAGAGCACTCTTC
  AAAATACCAAGGAATCCACCCCCAAAACTAAGGCAGCCTGAGCTATGGTCAGCAGAATTC
  AATGACTTCATAAGCAAGTGCTTGACTAAAGATTATGAAAAGCGTCCAACAGTGTCAGAA
  CTTTTACAGCATAAATTCATTACTCAAATTGAGGGCAAAGATGTGATGCTACAAAAACAA
  CTAACGGAATTCATTGGCATCCATCAATGCATGGGAGGCACAGAAAAGGCCAGACGTGAA
  CGTATTCACACGAAGAAAGGGAACTTCAACCGACCTCTAATATCCAATCTGAAGGATGTA
  GATGATTTAGCAACCCTAGAAATTTTGGATGAGAATACAGTCTCAGAGCAACTTGAGAAG
  TGTTATTCCAGAGATCAGATCTACGTCTATGTGGGAGACATACTCATTGCTCTTAACCCT
  TTTCAGAGTCTGGGTCTTTACTCCACAAAGCATTCCAAACTATATATTGGATCAAAGAGA
  ACTGCCAGTCCTCCTCACATTTTTGCAATGGCTGACTTAGGATATCAATCTATGATAACA
  TATAATTCAGATCAGTGCATTGTTATTTCTGGAGAAAGTGGTGCTGGAAAGACTGAAAAT
  GCTCATCTTTTAGTTCAGCAGCTGACAGTGCTTGGAAAGGCTAATAACAGAACCTTGCAA
  GAGAAGATTTTACAAGTGAACAATTTGGTAGAAGCCTTTGGCAATGCCTGCACTATTATA
  AATGACAATTCTAGCAGATTTGGAAAATACTTAGAAATGAAATTCACCTCTTCTGGAGCG
  GTAGTGGGAGCACAGATTTCTGAATATCTCCTGGAAAAATCCCGAGTTATCCACCAAGCT
  ATTGGAGAAAAAAATTTTCATATTTTTTACTACATTTATGCTGGTTTGGCTGAAAAGAAG
  AAACTAGCCCATTACAAACTGCCTGAAAATAAGCCTCCCAGGTACCTACAAAATGACCAC
  CTCAGAACAGTACAAGACATCATGAATAATAGTTTCTATAAATCCCAGTATGAATTAATT
  GAGCAATGTTTCAAAGTCATAGGTTTTACAATGGAGCAACTTGGTAGTATATACAGCATA
  CTCGCTGCAATCTTGAATGTTGGCAACATTGAATTTTCTTCTGTGGCAACTGAACACCAG
  ATTGACAAGAGCCACATTTCTAATCATACAGCCCTGGAGAACTGTGCTTCTTTGCTTTGC
  ATTCGGGCAGATGAGCTACAAGAAGCTCTCACCTCCCACTGTGTGGTCACTAGAGGAGAA
  ACAATTATACGACCCAATACTGTAGAAAAAGCTACCGATGTCAGGGATGCCATGGCTAAA
  ACTTTATATGGACGTCTCTTTAGTTGGATAGTCAATTGCATTAACAGTTTGTTGAAGCAT
  GACTCATCACCAAGTGGGAATGGTGATGAGCTGAGCATTGGCATTCTTGATATATTTGGC
  TTTGAAAATTTCAAAAAAAATTCCTTCGAGCAGCTGTGCATTAACATTGCAAATGAACAA
  ATTCAGTATTATTATAATCAACATGTGTTTGCATGGGAACAGAATGAATACCTAAATGAA
  GATGTGGATGCTAGAGTTATTGAATATGAGGATAACTGGCCCCTCTTAGATATGTTTCTG
  CAAAAGCCAATGGGTTTACTTTCCCTACTTGATGAAGAAAGTAGATTTCCCAAGGCCACT
  GACCAGACTCTTGTAGAAAAATTTGAAGGTAACCTGAAATCACAATACTTCTGGAGACCC
  AAAAGAATGGAACTTAGTTTTGGAATTCACCATTATGCAGGAAAGGTCCTCTATAATGCA
  AGTGGATTCTTAGCCAAAAACAGAGACACTCTTCCTACTGACATTGTGCTACTTTTGAGG
  TCATCCGACAACAGTGTAATTAGGCAACTAGTCAACCACCCTCTGACCAAAACAGGTAAT
  CTGCCACATTCTAAAACTAAAAATGTTATAAACTATCAAATGAGGACTTCAGAAAAATTA
  ATCAACCTGGCAAAGGGCGACACTGGAGAAGCCACACGTCATGCCAGAGAGACAACCAAC
  ATGAAAACACAAACGGTTGCATCATATTTTAGATATTCCCTGATGGATTTGTTGTCTAAA
  ATGGTGGTGGGCCAACCTCATTTTGTCCGTTGCATCAAACCAAATAGTGAGCGTCAGGCA
  AGAAAATATGACAAAGAGAAAGTTCTGCTACAGCTTCGGTACACAGGAATTCTGGAAACA
  GCAAGAATTCGAAGACTAGGATTCTCCCATCGGATACTTTTTGCTAACTTTATAAAGCGG
  TACTACCTTCTCTGCTACAAGTCGAGCGAGGAGCCCCGCATGAGCCCTGACACCTGTGCC
  ACCATTTTGGAAAAAGCTGGTCTCGATAACTGGGCTCTTGGAAAAACAAAAGTGTTCCTT
  AAGTATTATCACGTGGAGCAGTTAAATCTAATGCGAAAGGAAGCTATTGACAAGCTTATT
  TTGATTCAAGCTTGTGTCAGAGCATTCTTGTGTTCAAGAAGATACCAAAAAATACAGGAG
  AAAAGGAAAGAAAGCGCTATAATAATACAGTCAGCTGCAAGAGGACACCTTGTCAGGAAA
  CAAAGAAAAGAAATTGTTGACATGAAAAACACAGCAGTAACAACCATTCAAACTTCTGAT
  CAGGAATTCGACTACAAGAAAAACTTTGAAAATACAAGGGAATCTTTCGTGAAGAAACAA
  GCAGAAAATGCAATCTCTGCTAATGAAAGATTCATTTCAGCTCCAAATAATAAAGGAAGT
  GTATCTGTAGTGAAGACTTCCACTTTCAAACCTGAAGAGGAAACCACCAATGCTGTGGAG
  AGTAACAACAGAGTGTATCAGACTCCAAAAAAAATGAATAATGTGTATGAGGAAGAGGTT
  AAGCAAGAATTCTACCTTGTAGGGCCAGAAGTAAGCCCCAAACAGAAGTCTGTCAAAGAC
  CTGGAAGAGAACAGCAATCTAAGGAAAGTGGAGAAAGAGGAAGCTATGATCCAGAGTTAC
  TATCAGAGGTACACAGAGGAGAGGAATTGTGAAGAGTCAAAAGCAGCATATCTAGAAAGG
  AAGGCCATATCAGAAAGGCCAAGCTACCCAGTGCCTTGGTTAGCTGAAAATGAGACTTCC
  TTTAAAAAAACTTTGGAACCTACACTTAGCCAAAGGTCAATTTATCAAAATGCAAACAGC
  ATGGAAAAAGAAAAGAAGACATCTGTAGTTACCCAGCGTGCACCGATATGCAGCCAGGAG
  GAAGGCAGAGGCCGTCTGAGGCATGAGACAGTCAAAGAGAGGCAAGTTGAACCAGTGACA
  CAGGCCCAGGAGGAAGAAGATAAAGCAGCGGTATTCATTCAGAGCAAATACCGGGGTTAC
  AAGAGAAGGCAGCAGTTGAGGAAGGACAAGATGTCTTCTTTTAAGCATCAGAGGATTGTC
  ACAACACCAACAGAAGTAGCAAGAAACACTCATAATTTGTATTCCTATCCCACAAAACAT
  GAGGAAATCAATAACATCAAGAAGAAGGATAACAAAGACTCGAAAGCAACTTCAGAAAGA
  GAAGCATGTGGTTTGGCAATTTTTTCAAAACAGATATCAAAGTTATCTGAAGAATATTTC
  ATTCTGCAGAAAAAATTGAATGAAATGATTTTGTCACAGCAACTGAAGTCACTTTATCTG
  GGTGTCTCGCACCATAAGCCAATTAATAGACGAGTTTCTTCTCAGCAGTGCCTCTCAGGT
  GTCTGTAAAGGAGAGGAGCCAAAAATATTGAGACCCCCAAGACGACCCCGGAAACCCAAA
  ACATTAAATAACCCTGAAGACTCCACATACTATTATCTACTTCATAAGTCAATCCAAGAA
  GAAAAACGAAGACCAAGGAAAGACAGTCAGGGAAAATTATTAGATTTGGAAGATTTCTAT
  TATAAGGAATTTTTGCCCAGTCGTTCTGGACCAAAGGAACATAGCCCTAGTTTAAGAGAA
  CGAAGACCACAGCAAGAACTCCAGAATCAATGTATTAAGGCTAATGAAAGGTGCTGGGCG
  GCGGAGAGCCCCGAGAAGGAGGAGGAGAGAGAGCCAGCAGCCAACCCCTACGACTTCAGG
  AGGCTCCTGCGCAAAACCTCCCAGCGCCGGCGCCTCGTCCAGCAGTCCTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_017433
• ORF Size: 4851 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017433.3, NP_059129.2
• RefSeq Size: 5597
• RefSeq ORF: 4851
• Locus ID: 53904
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008]