PCDHAC1 (NM_018898) Human Untagged Clone

CAT#: SC304635

PCDHAC1 (untagged)-Human protocadherin alpha subfamily C, 1 (PCDHAC1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHAC1
• Synonyms: PCDH-ALPHA-C1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018898, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTGGGCTGTGGGGTGGCAGTTTTATGTTTGTGGGTTTCCTGCGGCGCTGCAGCGGGACAGCTCGAGT
  ACTCAGTGCCGGAGGAGACGGAGCGGGGCGTAGCCGTAGGCAATCTCTCCGCGGACTTGAGGCTGCCAGC
  GGCCGCTATGTCCTCGCGGAACTTTCGCTTCCTTTCCAGCCACCGCGAGCTCTACTTCGGGGTGGATCTA
  CCCAGCGGCAATTTGGTGGTCAGAGAGCCGGCGGACCGCGAACAGCTGTGCAGGGCCAAAGCTGCCTGCG
  TCTTGACCTACGACCTGGTGCTCGAGGACCCGCTGGAGCTGCACAAGATTCGGATTCACGTCCTGGACAC
  CAATGACAACTCACCTCTCTTTCCTGCCGGCGACGTGCAGCTGCACATCCCCGAGTTCCTGACGCCCGGA
  GCCCGCTTTACTCTCCCGAATGCCCAAGATGACGACGAGGGAAGCAATGGGATACTAAGCTACAGCCTAA
  GCCCCAGTCAGCACTTTCGCCTGGACATGGGATCGCGGGTTGACGGCAGCGAATACCCGGAGTTGGTGTT
  GGAGAAAGCACTGGATCGCGAACAGCGCGCCACCCACCTGCTGGTGCTTACAGCTCGGGACGGCGGGCTA
  CCTGCCCGCTCAGGAGACGCACAAGTCACCATCATTGTGGTGGACACAAATGACAACGCGCCTGTATTTG
  AGCGCTCCGTATACCGCACCAAGGTTCCAGAGACTGCACCCAATGGGACTGTGTTATTCCGAGTTCAAGC
  CTTGGATCCAGATGAAGGGTCCAATGGGGAAGTCCAGTACTCCCTAAGCAACAGCACGCAAGCAGAGCTG
  CGACACCGCTTTCACGTGCACCCTAAAAGTGGGGAGGTGCAAGTAGCTGCTTCACTAGGTCCGCCTGAAA
  CGCTCTTGGAGGCATACATTGAGGCGAGGGACGAAGGTGTCTTTGGTTTAGCTAGCACCGCTAAACTGCT
  GGTGGAGGTGACTGACGTGAACGATCATGCCCCCGAACTGGACTTCCTGACTCTTTCGAACCCAGTACCT
  GAGGACGCTGCCCCTGGCACAGTGATTGCTCTCTTTAGTGTAAAGGATGAAGACCTCGATTCTAATGGTA
  GGGTCATTTGTGGCATGTCTAGTGCAGGCCCTTTTCAGCTGACGGCTTCCTTTGACAACTACTACAGCCT
  GCTGATTGATGGGCCCCTGGACCGGGAGCAGATCAGTGAATACCAAGTCCTGATCACGGCCTCAGATAGT
  GGCTCACCCCCACTTAGCACCCGAAGGACAATCACTGTGTCAGTTGCTGATGTGAATGACAATACACCAA
  ACTTTCCTCAACCCCAGCAGGAACTTTTCGTTGCTGAAAACAATGGCCCTGGGGCCTCTCTAGGCCGAGT
  GTTTGCCCAGGACCCCGACCTGGGGAAGAATGGCCTTGTCTCTTATGAGCTGTTGGATGTTATCTCTGAA
  GGGCCATCAGCCTCTAGCTTGCTGGCAGTGGAATCATCCAGTGGGGCCATCACTGCCAAAACTTCCTTTG
  ACTTTGAGCAGCTCAGGGGGTTTCATTTCCAAGTAGAAGGCCGGGATGGTGGCATTCCTCCCAGAAGTGC
  AACAGTGACTATAAACTTGTTTGTGGTAGATAGGAATGACAATTATCCGGTTATCTTGTTTCCCTTGCCC
  AGAAATGGTTCTGTCCCAGTGGAAATTGTGCCCCGCTCTGCCAGGACTGGACACTTGGTCACAAAAGTGG
  TAGCAGAGGATGCTGACAGTGGTTCTAATGCCTGGCTTTCCTACCACATCTCCCGGGCGTCTGACTCTAG
  TCTCTTTAGAATTTCAGCCAATATAGGTGAGCTCCGTACTGCTCGCTTAGTTCTTCCCACTGATGCAGTT
  AAGCAGAGGGTGGTGGTAGTGGTTCGGGACCATGGAGACCCACCACTTTCCTCCTCTGTCACTCTGGGTG
  TGCTGTTGAGCAACTCTGTCCCTCAGTTACTTCCAGACTTTGAAGATGTCTGGGAACCAGGAGGGCAGCT
  TTCTGCCCAGAACTTGTATTTAGTAATTGCCTTGGCTTGTATTTCCTTTTTATTTCTGGGGTGCTTACTT
  TTCTTCGTGTGTACCAAGTTGCACCAGAGCCCAGGCTGTTGCGCTCAGAGCTGCTGTCGCTCTACAGAGG
  ATCTGAGGTATGGAAGTAAGATGGTTTCAAATCCTTGCATGACATCAGCCACCATAGATGTCACTACAGT
  TGAGAGACTTTCTCAGACTTATCTCTATCGGGCCTCTCTGGGACTTGGTTCTGATAATAACAGTTTGCTG
  TTGCGTGGGGAGTACAATGCTGCCGACCTGCGAAATCTTGCCACTGGGGTAGGACTGAATTTGCCAATAT
  CCTGTATTCAGATTCGGAATAGGAAAGGGGATCACGCTAATGTCAATGCCATGCCACGACAGCCCAACCC
  TGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCACCTAGAGGAGGCTGGCATT
  CTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACAGTATCCAGTGCAACACCAGAACCAGAGG
  CAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACAGCTGGACCTTTAAATACGGACCAGG
  CAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAATTCATTATCCCAGGATCTCCTGCAATCATC
  TCCATCCGGCAGGAGCCTACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAGG
  AGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGGAACAGCAC
  GACTGACAACAGTGACCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_018898
• ORF Size: 2892 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018898.3, NP_061721.2
• RefSeq Size: 5475
• RefSeq ORF: 2892
• Locus ID: 56135
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1).