INCENP (NM_020238) Human Untagged Clone

CAT#: SC304727

INCENP (untagged)-Human inner centromere protein antigens 135/155kDa (INCENP), transcript variant 2


  "NM_020238" in other vectors (2)

Reconstitution Protocol

USD 1,850.00

4 Weeks*

Size
    • 10 ug

Product Images

Other products for "INCENP"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol INCENP
Synonyms FLJ31633; MGC111393
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_020238, the custom clone sequence may differ by one or more nucleotides
ATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATG
GAGTTTCTCTGCAACATGGATAATAAGGACTTGGTGTGGCTTGAGGAAATCCAAGAGGAG
GCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCT
TCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGAT
CCCATCAGGAGAAGGTTATCCCGCAGAAAGTCTCGGAGCAGCCAGCTGAGCTCCCGACGC
CTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTC
CTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCA
CCTTCTTCACCCACCCCTGAGTCTCCCACGATGCTGACTAAGAAGCCCGAGGATAACCAC
ACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAG
CAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCA
GCTTCAGCCACAGCTCCAACCTCCCAGGGCATCCCGACATCAGATGAGGAATCAACACCT
AAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCC
CAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCG
CAGGTCTCCCCTGGCCCACGGGACTCGCCAGCCTTTCCAGATTCTCCATGGCGGGAGCGG
GTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCT
CAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAG
AAGTACTCTCTGGTGGCCAAACAGGAAAGTGTTGTCCGCAGGGCGAGCAGAAGGCTTGCC
AAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAG
AGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAG
GAGGCTGAGCCTGTGGCGGCAGCTGAGCCAGAGGTCCCTGAGAACAATGGAAATAACTCG
TGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGC
AGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCC
AGAGAGCCACCGCAGAGTGCCAGGAGGAAGCGCAGCTACAAGCAGGCCGTGAGTGAGCTG
GACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCC
TCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAG
AGGAACCAGATGCTCATGACCCCGACCTCAGCCCCACGCAGCGTCATGAAGTCCTTTATT
AAGCGCAACACTCCCCTGCGCATGGACCCCAAGGAGAAGGAGCGGCAGCGCCTGGAGAAT
CTGCGGCGGAAGGAGGAGGCCGAGCAGCTGCGCAGGCAGAAGGTGGAGGAGGACAAGCGG
CGGCGGCTGGAGGAGGTGAAGCTGAAGCGTGAGGAACGCCTCCGCAAGGTGCTGCAGGCC
CGCGAGCGGGTGGAGCAGATGAAGGAGGAGAAGAAGAAGCAGATTGAGCAGAAGTTTGCT
CAGATCGACGAGAAGACTGAGAAGGCCAAGGAGGAGCGGCTGGCAGAGGAGAAGGCCAAG
AAAAAGGCGGCGGCCAAGAAGATGGAGGAGGTGGAAGCACGCAGGAAGCAGGAAGAGGAG
GCACGTAGGCTCAGGTGGCTGCAGCAGGAGGAGGAAGAGCGGCGGCACCAAGAGCTGCTG
CAGAAGAAGAAGGAAGAGGAGCAGGAGCGGCTGCGGAAGGCGGCCGAGGCTAAGCGGCTG
GCAGAGCAGCGGGAGCAGGAGCGGCGGGAGCAGGAGCGGCGCGAGCAGGAGCGGCGCGAG
CAGGAGCGGCGGGAGCAGGAGCGGCGCGAGCAGGAGCGACAGCTGGCAGAGCAGGAGCGT
CGGCGGGAGCAGGAGCGGCTCCAGGCCGAGAGGGAGCTGCAGGAGCGGGAGAAGGCCCTG
CGGCTGCAGAAGGAGCAGCTGCAGAGGGAACTGGAGGAGAAGAAGAAGAAGGAAGAGCAG
CAGCGTCTGGCTGAGCGGCAGCTGCAGGAGGAGCAAGAGAAGAAAGCCAAGGAGGCAGCA
GGGGCCAGCAAGGCCCTGAATGTGACTGTGGACGTGCAGTCTCCAGCTTGTACCTCATAT
CAGATGACTCCGCAAGGGCACAGGGCCCCTCCCAAGATCAACCCAGATAACTACGGGATG
GATCTGAATAGCGACGACTCCACCGATGATGAGGCCCATCCCCGGAAGCCCATCCCCACC
TGGGCCCGAGGCACCCCGCTCAGCCAGGCTATCATTCACCAGTACTACCACCCACCGAAC
CTTCTGGAGCTCTTTGGAACCATTCTCCCACTGGACTTGGAGGATATCTTCAAGAAGAGC
AAGCCCCGCTATCACAAGCGCACCAGCTCTGCTGTCTGGAACTCACCGCCCCTGCAGGGC
GCCAGGGTCCCCAGCAGCCTGGCCTACAGCCTGAAGAAGCACTGA
Restriction Sites Please inquire     
ACCN NM_020238
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_020238.1, NP_064623.1
RefSeq Size 3536 bp
RefSeq ORF 2760 bp
Locus ID 3619
Cytogenetics 11q12.3
Protein Families Druggable Genome
Gene Summary 'In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).[supplied by OMIM, Mar 2008]'
Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.