PRDM16 (NM_022114) Human Untagged Clone

CAT#: SC304995

PRDM16 (untagged)-Human PR domain containing 16 (PRDM16), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRDM16
• Synonyms: CMD1LL; KMT8F; LVNC8; MEL1; PFM13
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_022114 edited
  GGAGGAGGAGAGAGATTCCGCGAGCCGACACCATGCGATCCAAGGCGAGGGCGAGGAAGC
  TAGCCAAAAGTGACGGTGACGTTGTAAATAATATGTATGAGCCCAACCGGGACCTGCTGG
  CCAGCCACAGCGCGGAGGACGAGGCCGAGGACAGTGCCATGTCGCCCATCCCCGTGGGGC
  CACCGTCCCCCTTCCCCACCAGCGAGGACTTCACCCCCAAGGAGGGCTCGCCGTACGAGG
  CCCCTGTCTACATTCCTGAAGACATTCCGATCCCAGCAGACTTCGAGCTCCGAGAGTCCT
  CCATCCCAGGGGCTGGCCTGGGGGTCTGGGCCAAGAGGAAGATGGAAGCCGGGGAGAGGC
  TGGGCCCCTGCGTGGTGGTGCCCCGGGCGGCGGCAAAGGAGACAGACTTCGGATGGGAGC
  AAATACTGACGGACGTGGAAGTGTCGCCCCAGGAAGGCTGCATCACAAAGATCTCCGAAG
  ACCTGGGCAGTGAGAAGTTCTGCGTGGATGCAAATCAGGCGGGGGCTGGCAGCTGGCTCA
  AGTACATCCGTGTGGCGTGCTCCTGCGATGACCAGAACCTCACCATGTGTCAGATCAGTG
  AGCAGATTTACTATAAAGTCATTAAGGACATTGAGCCAGGTGAGGAGCTGCTGGTGCACG
  TGAAGGAAGGCGTCTACCCCCTGGGCACAGTGCCGCCCGGCCTGGACGAGGAGCCCACGT
  TCCGCTGTGACGAGTGTGACGAACTCTTCCAGTCCAAGCTGGACCTGCGGCGCCATAAGA
  AGTACACGTGTGGCTCAGTGGGGGCTGCGCTCTACGAGGGCCTGGCTGAGGAGCTCAAGC
  CCGAGGGCCTTGGCGGTGGCAGCGGCCAAGCCCACGAGTGCAAGGACTGCGAGCGGATGT
  TCCCCAACAAGTACAGCCTGGAGCAGCACATGGTCATCCACACGGAGGAGCGCGAGTACA
  AATGCGACCAGTGTCCCAAGGCCTTCAACTGGAAGTCCAACCTCATCCGCCACCAGATGT
  CCCACGACAGCGGCAAACGCTTCGAATGTGAAAACTGCGTGAAGGTGTTCACGGACCCCA
  GCAACCTTCAGCGGCACATCCGCTCGCAGCACGTGGGCGCTCGGGCCCACGCCTGCCCCG
  ACTGCGGGAAGACCTTCGCCACGTCCTCCGGCCTCAAGCAGCACAAGCATATCCACAGCA
  CGGTGAAGCCTTTCATATGTGAGGTCTGCCACAAGTCCTACACGCAGTTCTCCAACCTGT
  GCCGGCACAAGCGGATGCACGCCGACTGCCGCACGCAGATCAAGTGCAAGGACTGTGGCC
  AGATGTTCAGCACTACCTCCTCCCTCAACAAGCACCGGCGCTTCTGCGAGGGCAAGAACC
  ATTACACGCCGGGCGGCATCTTTGCCCCGGGCCTGCCCTTGACCCCCAGCCCCATGATGG
  ACAAGGCAAAACCCTCCCCCAGCCTCAATCACGCCAGCCTGGGCTTCAACGAGTACTTTC
  CCTCCAGGCCGCACCCGGGGAGCCTGCCCTTCTCCACGGCGCCTCCCACGTTCCCCGCAC
  TCACCCCCGGCTTCCCGGGCATCTTCCCTCCATCCTTGTACCCCCGGCCGCCTCTGCTAC
  CTCCCACACCGCTGCTCAAGAGCCCCCTGAACCACACCCAGGACGCCAAGCTCCCCAGTC
  CCCTGGGGAACCCAGCCCTGCCCCTGGTCTCCGCCGTCAGCAACAGCAGCCAGGGCACGA
  CGGCAGCTGCGGGGCCCGAGGAGAAGTTCGAGAGCCGCCTGGAGGACTCCTGTGTGGAGA
  AGCTGAAGACCAGGAGCAGCGACATGTCGGACGGCAGTGACTTTGAGGACGTCAACACCA
  CCACGGGGACCGACCTGGACACGACCACGGGGACGGGCTCGGACCTGGACAGCGACGTGG
  ACAGCGACCCTGACAAGGACAAGGGCAAGGGCAAGTCCGCCGAGGGCCAGCCCAAGTTTG
  GGGGCGGCTTGGCGCCCCCGGGGGCCCCGAACAGCGTGGCCGAGGTGCCTGTCTTCTATT
  CCCAGCACTCATTCTTCCCGCCACCCGACGAGCAGCTGCTGACTGCAACGGGCGCCGCCG
  GGGACTCCATCAAGGCCATCGCATCCATTGCCGAGAAGTACTTTGGCCCCGGCTTCATGG
  GGATGCAGGAGAAGAAGCTGGGCTCGCTCCCCTACCACTCGGCGTTCCCCTTCCAGTTCC
  TGCCCAACTTCCCCCACTCCCTTTACCCCTTCACGGACCGAGCCCTCGCCCACAACTTGC
  TGGTCAAGGCCGAGCCAAAGTCACCCCGGGACGCCCTCAAGGTGGGCGGCCCCAGTGCCG
  AGTGCCCCTTTGATCTCACCACCAAGCCCAAAGACGTGAAGCCCATCCTGCCCATGCCCA
  AGGGCCCCTCGGCCCCCGCATCCGGCGAGGAGCAGCCGCTGGACCTGAGCATCGGCAGCC
  GGGCCCGTGCCAGCCAAAACGGCGGCGGGCGGGAGCCCCGCAAGAACCACGTCTATGGGG
  AACGCAAGCTGGGCGCCGGCGAGGGGCTGCCCCAGGTGTGCCCGGCGCGGATGCCCCAGC
  AGCCCCCGCTCCACTACGCCAAGCCCTCGCCCTTCTTCATGGACCCCATCTACAGCAGGG
  TAGAAAAGCGGAAGGTCACAGACCCCGTGGGAGCCCTGAAGGAGAAGTACCTGCGGCCGT
  CCCCGCTGCTCTTCCACCCCCAGATGTCAGCCATAGAGACCATGACAGAGAAGCTGGAGA
  GCTTTGCAGCCATGAAGGCGGACTCGGGCAGCTCCCTGCAGCCCCTCCCCCACCACCCCT
  TCAACTTCCGGTCCCCACCCCCAACGCTCTCCGACCCCATCCTCAGGAAGGGCAAGGAGC
  GATACACGTGCAGGTACTGTGGGAAGATCTTCCCCAGATCAGCCAATCTCACCAGACACC
  TGAGGACGCACACTGGGGAGCAGCCGTACAGGTGTAAGTACTGCGACCGCTCCTTCAGCA
  TCTCTTCGAACCTCCAGCGGCACGTCCGGAACATCCACAACAAGGAGAAGCCTTTCAAGT
  GCCACCTGTGCAACCGCTGCTTCGGGCAGCAGACCAACCTGGACCGGCACCTCAAGAAGC
  ACGAGCACGAGAACGCACCAGTGAGCCAGCACCCCGGGGTCCTCACGAACCACCTGGGGA
  CCAGCGCGTCCTCTCCCACCTCAGAGTCGGACAACCACGCACTTTTAGACGAGAAAGAAG
  ACTCTTATTTCTCGGAAATCAGAAACTTTATTGCCAATAGTGAGATGAACCAAGCATCAA
  CGCGAACAGAGAAACGGGCGGACATGCAGATCGTGGACGGCAGTGCCCAGTGTCCAGGCC
  TAGCCAGTGAGAAGCAGGAGGACGTGGAGGAGGAGGACGACGATGACCTGGAGGAGGACG
  ATGAGGACAGCCTGGCCGGGAAGTCGCAGGATGACACCGTGTCCCCCGCACCCGAGCCCC
  AGGCCGCCTACGAGGATGAGGAGGATGAGGAGCCAGCCGCCTCCCTGGCCGTGGGCTTTG
  ACCACACCCGAAGGTGTGCTGAGGACCACGAAGGCGGTCTGTTAGCTTTGGAGCCGATGC
  CGACTTTTGGGAAGGGGCTGGACCTCCGCAGAGCAGCTGAGGAAGCATTTGAAGTTAAAG
  ATGTGCTTAATTCCACCTTAGATTCTGAGGCTTTAAAACATACACTGTGCAGGCAGGCTA
  AGAACCAGGCATATGCAATGATGCTGTCCCTTTCCGAAGACACTCCTCTCCACACCCCCT
  CCCAGGGTTCTCTGGACGCTTGGTTGAAGGTCACTGGAGCCACGTCGGAGTCTGGAGCAT
  TTCACCCCATCAACCACCTCTGACGGGCTGGGCAGCCGGGGGCCGGTGGCCAGAGCGAGG
  GCACCAGCCACGAAGGACGGAGGCGGGCGGGGCCCCGGAGAACCCTGTCCCTGCGTGTGG
  CCACTCCTCAGCATCCTCCCCACCCACCATGGTTCATTCCGACTTTTCCAATGGAAACTC
  AGATCCCAAAAGTCCCTAAAGCAGTCGTAGAGTCTCACCATCTCCAAGGATTGGTCTTGA
  GAACACTGTTCAGTGACGGCCATGCAGGTGGCCGTCCAAAGACAGCCAACGGAGCTGCCT
  CGCAGAATCAGCCAGTGGGCAGGTGGACGCTCTGCTGAGACAGAAGCTGGTGGCCACTGC
  CGGGTGCCCGCGTGGGGTCGCGGAAGGGAATGGATAGACTGGTGTGCTCAAAAGAGAGAG
  ATCACTCAAATGATTTTTATAATGAAATGACAAGAATAACCCTTTTGGTAACCGTATTGA
  CTGCAGAGTCTATTTAAGCATGTGGTTTTAAAAATAGACAGTATTTTTTAAAAATCAAAA
  AATGACTTGCAAATTGTTTTTTAAAAGTAATTTTGCATTGCTTTGAAATTTGAGCTCATT
  TGCAAACCCGAGTCTGCCTGGGAACCCGCACTGTGCCTGGGTGTATTCTTTATACTGTAG
  ATAATGGAGAAATTTTCTATCTCTGTCCCTATTTGTATAAGCCAAGGTGATGCTGGGTGC
  CCCGAGGCAGAACAAGAGGCGCGGGGCCACACCCGTGAACCATGCAGACGGCCGAAGAAG
  TCTTAGGCAGGGCGCCCTGGGCTGCAGGCCTGCCCGAGGCTGGGATGGGAAGTGTGCCTG
  CCCTCGTGTGACATGGAATTGGTGTCAGGACCGCCACGTGGCCTTCAGAGGAATCCACAG
  GTCCCCACCCAAGATCCCTCAATTATATGGGGAAGTCGAGGGCCTGTGGCTTGGATCCGC
  CATGCAGAGATGTGGCCGGGCACCCATCTTCCTTCCCTCCTCTGTCCCTGCCTCGGCCAC
  CCCACGCGGGAACCCAGCGCCGTCCTCTGAAGGCAGGGCCTTGGCCACGTCCTGGGTCTC
  CCACCTCCCACCTGACCCCAGCGGCTCCGGTGTCCTCCACGTGGCTGCCCTGGGGAGCAA
  TCCCAGCGGATCGCTCCGGGCCACCAAGCCGCACCTGTGCCTGAGACTCCGGATGGACGA
  CACAGTCGTCACGTCGCTCTTCCTGCGGGTTCTTGGCGAGACACAGCTTGAGAACAGAAG
  GGCGTCGGGGGAACCTGCCGCAAGGAGCAGAGACAGCACAGCCCCCCGGGCCCAGCCGCC
  TCCCTCTCTTGGGACGCAACTTCTTCCCCACTCGGATGGGCTTTAAATTATTCCCATAGG
  GGCCAATTTCAAATAATAATTTTTTTCCCTGATGGAATTTACCTTAATCTGTATATAACT
  TGTAATTTTTTCTAATTCATTTCTTTTCTTATTTTATTTCCTCCTTAACAGTATTTTTGG
  CATTAGACATTCTTATTGTGAAGAAATAATGTTAATATAAGTATCTGGTGAAGGACCAAA
  ACCGTGTGATAAGGTTGTGTGTCGTGTGGGAGTGGGGCGATTTTTTATGTGCCAAATACC
  CCCGTCCCCCCCATGAATCCTGCTGTCCCTGCTGCCGTTTACCAGACAATCATATGTTTT
  TGTTAAATTTGCGTTTCAGTTACATTTGCATTTAAGACAAGTGTTCTATTTATTTCTTGT
  ATTGTTTGGAAGAAAAAATGATGATAGAGTCCCAAAAAGAAGAGAAAAAAAATGCCCAAG
  TTGCCCTTTAAAAAAAAAGAGCGTAAATACAAACAGGAGTGGTGCAAGCCGCCTTGGTGT
  GGGTTTGTGTCACGCGTGGACATCTCCTCAGGCTTTGTGTCACGCGTGGACATCTCCTCA
  GGCTGTCCCCAGCGGTGACGGGAGGTGTCCTGGCTGCTCCAGGACAAAAGACAATCGTCT
  CTGTGGGTGCCGGGCGGTCCAGGCTTGCACTGAAGACGTGCCACGGGGAGGCTCCTGCAG
  GAGGCTCAACCCGACGGATCACAGTGAAAGGGATTCCTCCCACGCCAGATCTGCACAACG
  AGGCAAGACAGGACCCACCTGTGCGTGCGCTGGGGCCATGGGGTGGCCCCCCCGGGGCAG
  CGGGGGAGCTGCCTGCAGAAGAGCCAGCCGGCGTGTCGGGAAGGATCCAGGATCTGCAAA
  CACAACCGCTCAGGCCTTCTCACGCGTTTCCACAACATCCCCTGGGTCAGACCCACCAGG
  TACC
  
• Restriction Sites: Please inquire
• ACCN: NM_022114
• ORF Size: 3828 bp
• Insert Size: 6100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP and 3bp insertion compared with NM_022114.2.

Reference Data

• RefSeq: NM_022114.2, NP_071397.2
• RefSeq Size: 8726
• RefSeq ORF: 3828
• Locus ID: 63976
• Gene Summary: The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.