PCDHAC1 (NM_031882) Human Untagged Clone

CAT#: SC305351

PCDHAC1 (untagged)-Human protocadherin alpha subfamily C, 1 (PCDHAC1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHAC1
• Synonyms: PCDH-ALPHA-C1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031882, the custom clone sequence may differ by one or more nucleotides
  ATGGTGGGCTGTGGGGTGGCAGTTTTATGTTTGTGGGTTTCCTGCGGCGCTGCAGCGGGA
  CAGCTCGAGTACTCAGTGCCGGAGGAGACGGAGCGGGGCGTAGCCGTAGGCAATCTCTCC
  GCGGACTTGAGGCTGCCAGCGGCCGCTATGTCCTCGCGGAACTTTCGCTTCCTTTCCAGC
  CACCGCGAGCTCTACTTCGGGGTGGATCTACCCAGCGGCAATTTGGTGGTCAGAGAGCCG
  GCGGACCGCGAACAGCTGTGCAGGGCCAAAGCTGCCTGCGTCTTGACCTACGACCTGGTG
  CTCGAGGACCCGCTGGAGCTGCACAAGATTCGGATTCACGTCCTGGACACCAATGACAAC
  TCACCTCTCTTTCCTGCCGGCGACGTGCAGCTGCACATCCCCGAGTTCCTGACGCCCGGA
  GCCCGCTTTACTCTCCCGAATGCCCAAGATGACGACGAGGGAAGCAATGGGATACTAAGC
  TACAGCCTAAGCCCCAGTCAGCACTTTCGCCTGGACATGGGATCGCGGGTTGACGGCAGC
  GAATACCCGGAGTTGGTGTTGGAGAAAGCACTGGATCGCGAACAGCGCGCCACCCACCTG
  CTGGTGCTTACAGCTCGGGACGGCGGGCTACCTGCCCGCTCAGGAGACGCACAAGTCACC
  ATCATTGTGGTGGACACAAATGACAACGCGCCTGTATTTGAGCGCTCCGTATACCGCACC
  AAGGTTCCAGAGACTGCACCCAATGGGACTGTGTTATTCCGAGTTCAAGCCTTGGATCCA
  GATGAAGGGTCCAATGGGGAAGTCCAGTACTCCCTAAGCAACAGCACGCAAGCAGAGCTG
  CGACACCGCTTTCACGTGCACCCTAAAAGTGGGGAGGTGCAAGTAGCTGCTTCACTAGGT
  CCGCCTGAAACGCTCTTGGAGGCATACATTGAGGCGAGGGACGAAGGTGTCTTTGGTTTA
  GCTAGCACCGCTAAACTGCTGGTGGAGGTGACTGACGTGAACGATCATGCCCCCGAACTG
  GACTTCCTGACTCTTTCGAACCCAGTACCTGAGGACGCTGCCCCTGGCACAGTGATTGCT
  CTCTTTAGTGTAAAGGATGAAGACCTCGATTCTAATGGTAGGGTCATTTGTGGCATGTCT
  AGTGCAGGCCCTTTTCAGCTGACGGCTTCCTTTGACAACTACTACAGCCTGCTGATTGAT
  GGGCCCCTGGACCGGGAGCAGATCAGTGAATACCAAGTCCTGATCACGGCCTCAGATAGT
  GGCTCACCCCCACTTAGCACCCGAAGGACAATCACTGTGTCAGTTGCTGATGTGAATGAC
  AATACACCAAACTTTCCTCAACCCCAGCAGGAACTTTTCGTTGCTGAAAACAATGGCCCT
  GGGGCCTCTCTAGGCCGAGTGTTTGCCCAGGACCCCGACCTGGGGAAGAATGGCCTTGTC
  TCTTATGAGCTGTTGGATGTTATCTCTGAAGGGCCATCAGCCTCTAGCTTGCTGGCAGTG
  GAATCATCCAGTGGGGCCATCACTGCCAAAACTTCCTTTGACTTTGAGCAGCTCAGGGGG
  TTTCATTTCCAAGTAGAAGGCCGGGATGGTGGCATTCCTCCCAGAAGTGCAACAGTGACT
  ATAAACTTGTTTGTGGTAGATAGGAATGACAATTATCCGGTTATCTTGTTTCCCTTGCCC
  AGAAATGGTTCTGTCCCAGTGGAAATTGTGCCCCGCTCTGCCAGGACTGGACACTTGGTC
  ACAAAAGTGGTAGCAGAGGATGCTGACAGTGGTTCTAATGCCTGGCTTTCCTACCACATC
  TCCCGGGCGTCTGACTCTAGTCTCTTTAGAATTTCAGCCAATATAGGTGAGCTCCGTACT
  GCTCGCTTAGTTCTTCCCACTGATGCAGTTAAGCAGAGGGTGGTGGTAGTGGTTCGGGAC
  CATGGAGACCCACCACTTTCCTCCTCTGTCACTCTGGGTGTGCTGTTGAGCAACTCTGTC
  CCTCAGTTACTTCCAGACTTTGAAGATGTCTGGGAACCAGGAGGGCAGCTTTCTGCCCAG
  AACTTGTATTTAGTAATTGCCTTGGCTTGTATTTCCTTTTTATTTCTGGGGTGCTTACTT
  TTCTTCGTGTGTACCAAGTTGCACCAGAGCCCAGGCTGTTGCGCTCAGAGCTGCTGTCGC
  TCTACAGAGGATCTGAGGTATGGAAGTAAGATGGTTTCAAATCCTTGCATGACATCAGCC
  ACCATAGATGTCACTACAGTTGAGAGACTTTCTCAGACTTATCTCTATCGGGCCTCTCTG
  GGACTTGGTTCTGATAATAACAGTTTGCTGTTGCGTGGGGAGTACAATGCTGCCGACCTG
  CGAAATCTTGCCACTGGGGTAGGACTGAATTTGCCAATATCCTGTATTCAGATTCGGAAT
  AGGAAAGGGGATCACGCTAATGTCAATGCCATGGTAAGCAAATTTTATGGAATTTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_031882
• ORF Size: 2457 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031882.2, NP_114088.2
• RefSeq Size: 3084
• RefSeq ORF: 2457
• Locus ID: 56135
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.