PCDHGA1 (NM_031993) Human Untagged Clone

CAT#: SC305383

PCDHGA1 (untagged)-Human protocadherin gamma subfamily A, 1 (PCDHGA1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGA1
• Synonyms: PCDH-GAMMA-A1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031993, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGATTCAGAAAAAGCTGACTGGCTGCAGCAGGCTGATGCTTCTGTGTCTTTCTCTGGAGCTGCTGT
  TGGAAGCTGGGGCTGGGAATATTCACTACTCAGTGCCGGAAGAGACAGACAAAGGTTCCTTCGTAGGCAA
  CATCGCCAAGGACCTAGGGCTGCAACCCCAGGAGCTGGCAGATGGCGGAGTCCGCATCGTCTCCAGAGGT
  AGGATGCCGCTTTTCGCTCTGAATCCTAGAAGTGGCAGCTTGATCACCGCGCGCAGGATAGACCGGGAGG
  AGCTCTGCGCTCAGAGCATGCCGTGTCTCGTGAGTTTTAATATCCTTGTTGAGGATAAAATGAAGCTTTT
  TCCTGTTGAAGTAGAAATAATTGATATTAATGACAACACTCCCCAATTCCAGTTAGAGGAACTGGAGTTT
  AAAATGAATGAAATAACGACTCCAGGTACCAGAGTCTCATTGCCTTTTGGGCAAGACCTTGATGTGGGTA
  TGAACTCACTCCAGAGCTACCAACTCAGCTCTAACCCTCATTTCTCCCTGGATGTGCAACAGGGAGCCGA
  TGGGCCTCAACATCCAGAGATGGTGCTGCAGAGTCCCTTAGACAGAGAAGAAGAAGCTGTCCACCACCTC
  ATCCTCACAGCTTCTGATGGGGGTGAACCAGTCCGTTCAGGGACCCTCAGAATTTACATTCAGGTGGTGG
  ATGCAAATGACAATCCTCCAGCATTTACTCAGGCACAATACCATATAAATGTCCCCGAAAACGTGCCGCT
  GGGTACTCAGCTGCTCATGGTAAATGCCACTGACCCTGATGAGGGAGCCAATGGGGAAGTAACGTACTCC
  TTTCACAATGTAGACCACAGAGTGGCCCAAATATTTCGTTTAGATTCTTACACAGGAGAAATATCAAATA
  AAGAACCACTAGATTTCGAAGAATACAAAATGTATTCAATGGAAGTTCAAGCCCAGGATGGTGCGGGGCT
  CATGGCTAAAGTTAAGGTACTGATCAAAGTTTTGGATGTAAATGATAATGCCCCAGAAGTGACCATCACC
  TCTGTCACCACTGCAGTTCCAGAAAACTTTCCTCCTGGGACCATAATTGCTCTTATCAGTGTGCATGACC
  AGGACTCAGGAGACAATGGCTACACCACATGTTTCATTCCTGGAAATTTACCCTTTAAATTGGAAAAGTT
  AGTTGATAATTATTACCGTTTAGTGACTGAAAGAACACTGGACAGAGAACTTATCTCTGGGTACAACATC
  ACAATAACAGCAATAGACCAAGGAACTCCAGCTCTATCTACTGAAACTCACATTTCACTACTAGTGACAG
  ATATCAATGACAACTCCCCAGTCTTCCATCAGGACTCCTACTCTGCCTACATTCCCGAAAACAACCCCAG
  AGGAGCCTCCATCTTCTCTGTGAGGGCCCACGACTTGGACAGCAATGAGAATGCACAAATCACTTACTCC
  CTAATAGAGGACACTATCCAGGGGGCACCCCTATCTGCCTACCTCTCCATCAACTCCGACACTGGGGTCC
  TGTATGCGCTGCGATCCTTCGACTATGAGCAGTTCCGGGACATGCAACTGAAAGTGATGGCGCGGGACAG
  TGGGGATCCGCCCCTCAGCAGCAACGTGTCTCTCAGCCTATTCCTGCTGGACCAGAACGACAACGCGCCC
  GAGATCCTGTACCCCGCCCTCCCCACAGATGGTTCTACCGGCGTGGAGCTGGCGCCCCTCTCCGCAGAGC
  CCGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGAGACTCGGGCCAGAACGCCTGGCTGTCCTACCG
  CCTGCTCAAGGCCAGCGAGCCGGGACTCTTCTCGGTGGGTCTGCACACGGGCGAGGTGCGCACGGCGCGA
  GCCCTGCTGGACAGAGACGCGCTCAAGCAGAGTCTCGTGGTGGCCGTCCAGGACCACGGCCAGCCCCCGC
  TCTCCGCCACTGTCACGCTCACCGTGGCCGTGGCCGACAGGATCTCCGACATCCTGGCCGACCTGGGCAG
  CCTCGAGCCCTCCGCCAAACCCAACGATTCGGACCTCACTCTGTACCTGGTGGTGGCGGCGGCCGCGGTC
  TCCTGCGTCTTCCTGGCCTTCGTCATCGTGCTGCTGGCGCACAGGCTGCGGCGCTGGCACAAGTCACGTC
  TGCTACAGGCTTCGGGAGGCGGCTTAGCGAGCATGCCCGGTTCGCACTTTGTGGGCGTGGACGGGGTTCG
  GGCTTTCCTGCAGACCTATTCCCACGAGGTCTCCCTCACTGCGGACTCGCGGAAGAGCCACCTGATTTTC
  CCCCAGCCCAACTATGCGGACACACTCATCAGCCAGGAGAGCTGTGAGAAAAAGGGTTTTCTATCAGCAC
  CCCAGTCTTTACTTGAAGACAAAAAGGAACCATTTTCTCAGGTAAACTTTTGTGATGAATGTATCAGCTA
  TCTAGAGAAAAATAATTCTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_031993
• ORF Size: 2472 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031993.1, NP_114382.1
• RefSeq Size: 2472
• RefSeq ORF: 2472
• Locus ID: 56114
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes the shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.