PCDHGB3 (NM_032097) Human Untagged Clone

CAT#: SC305397

PCDHGB3 (untagged)-Human protocadherin gamma subfamily B, 3 (PCDHGB3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGB3
• Synonyms: PCDH-GAMMA-B3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032097, the custom clone sequence may differ by one or more nucleotides
  ATGGGAAATAGCTCCGGATGGAGGGGCCCAGCAGGGCAGAGGCGAATGCTATTTCTCTTC
  CTGCTCTCTTTGTTAGACCAGGTTCTCTCCGAACCGATCCGCTACGCTATTCCCGAGGAG
  CTGGACAGGGGCTCGCTGGTAGGGAACCTCGCCAAGGACCTGGGGTTTGGCGTGGGGGAT
  TTACCTACTAGGAACCTGCGGGTTATTGCAGAGAAGAAATTCTTTACCGTGAGCCCCGAA
  AATGGGAACTTACTTGTGAGCGACCGTATAGACCGAGAGGAGATTTGTGGCAAGAAGTCG
  ACGTGTGTTCTGGAATTTGAAATGGTTGCTGAAAAGCCTTTAAACTTTTTTCATGTAACT
  GTGCTGATCCAGGATATTAACGACAACCCACCGACCTTTAGCCAAAATATCACTGAGCTG
  GAAATCAGCGAACTGGCTCTCACTGGAGCCACATTTGCCCTGGAATCTGCGCAAGATCCT
  GATGTAGGTGTCAATTCGCTGCAGCAGTACTACCTCAGCCCTGATCCGCACTTCTCTTTG
  ATTCAGAAGGAGAACCTGGATGGCAGTAGGTACCCAGAGCTAGTACTGAAAGCACCCCTG
  GACAGGGAAGAGCAGCCACATCACCACCTGGTCCTCACAGCTGTGGATGGGGGCGAGCCC
  TCCAGAAGCTGTACCACCCAGATCAGGGTAATTGTCGCAGATGCAAATGATAACCCCCCA
  GTATTTACTCAGGACATGTACAGGGTCAATGTTGCAGAGAACCTGCCCGCTGGCTCCTCC
  GTATTAAAAGTGATGGCCATTGACATGGATGAGGGCATCAATGCCGAAATCATCTATGCC
  TTCATCAATATTGGCAAGGAAGTGAGACAACTGTTCAAGCTGGACAGTAAAACGGGGGAA
  CTCACCACTATTGGAGAACTGGACTTTGAAGAGAGAGATAGCTACACAATTGGGGTGGAA
  GCAAAGGATGGTGGACATCACACTGCATATTGTAAAGTACAGATAGATATTTCAGATGAA
  AATGACAATGCCCCGGAGATAACCCTGGCTTCTGAATCCCAACATATACAAGAAGATGCT
  GAGCTGGGGACTGCCGTTGCCCTGATCAAAACACATGATCTAGATTCTGGATTTAATGGA
  GAAATCCTATGCCAACTAAAAGGAAACTTCCCCTTTAAAATCGTTCAAGATACCAAAAAC
  ACATACAGGTTGGTGACAGATGGAGCCCTGGACCGGGAGCAGATCCCAGAATACAATGTG
  ACGATCACAGCTACCGACAAAGGCAATCCACCGCTCTCCTCCAGCAAGACCATCACTCTG
  CACATCCTTGATGTCAACGACAACGTTCCCGTTTTCCACCAGGCCTCCTACACCGTGCAT
  GTAGCTGAGAACAATCCGCCTGGAGCCTCCATTGCGCATGTCAGAGCCTCGGATCCCGAC
  TTGGGACCTAATGGCCTTGTCTCCTACTACATCGTGGCCAGTGACCTGGAGCCGCGGGAG
  CTGTCGTCCTACGTGTCCGTGAGCGCGCGGAGCGGGGTGGTGTTCGCGCAGCGAGCCTTC
  GACCACGAGCAGCTGCGTGCCTTCGAGCTCACTCTGCAGGCCCGCGACCAGGGCTCGCCT
  ACGCTCAGCGCCAACGTGAGCCTGCGCGTGTTGGTGGACGACCGCAACGACAATGCACCG
  CTGGTGCTGTACCCAGCTCTGGGGCCCGAAGGCTCTGCGCTCTTCGATATGGTGCCGCGC
  TCTGCAGAGCCTGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGCAGACTCGGGATAC
  AACGCCTGGCTGTCCTACCACATTGTGCAGGCCAGCGAGCCCGGGCTGTTCAGCCTGGGC
  CTGCGCACGGGTGAGGTGCGCACGGCGCGTACCTTGGGCGACAGGGAGGCCGCCCGCCAG
  CGCCTGCTGGTCACTGTGCGTGATGGAGGACAGCAGCCTCTTTCAGCCACCGTCATGCTG
  CACCTAATCTTCGCAGATAGCTTGCAAGAGATACAACCTGACCTTAGCGACCGCCCCACT
  CCCTCTGACCCTCAGGCGGAGCTACAGTTTCACCTAGTAGTGGCGTTGGCCTTGATCTCA
  GTGCTCTTCCTCCTCGCGGTGATTCTGGCAATCTCCCTGCGCCTGCGATGCTCCTCCAGA
  CCCGCCACTGAGGGCTACTTTCAGCCTGGTGTCTGCTTCAAGACTGTACCTGGAGTTCTC
  CCCACCTACAGCGAAAGGACTTTGCCTTATTCCTACAATCCGTGTGCTGCCTCACATTCC
  TCAAACACCGAGTTTAAATTTCTCAATATAAAGGCTGAAAATGCTGCACCACAAGATCTT
  CTATGTGATGAAGCCTCTTGGTTTGAAAGTAATGACAATCCAGAAATGCCTTCTAATTCA
  GGCAATTTGCAAAAGGTGAGTTTCTTCAAACCTTTCCTTCCATAA
  
• Restriction Sites: Please inquire
• ACCN: NM_032097
• ORF Size: 2445 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032097.1, NP_115268.1
• RefSeq Size: 2445
• RefSeq ORF: 2445
• Locus ID: 56102
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks the constant region exons and contains an alternate 3' coding region compared to variant 1. The encoded isoform (2) has a shorter, distinct C-terminus than isoform 1.