IL27 (NM_145659) Human Untagged Clone

CAT#: SC306254

IL27 (untagged)-Human interleukin 27 (IL27)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL27
• Synonyms: IL-27; IL-27A; IL27A; IL27p28; IL30; p28
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_145659 edited
  GGGGACCAAAGAGGCTGGGCCCCGCCATGGGCCAGACGGCAGGCGACCTTGGCTGGCGGC
  TCAGCCTGTTGCTGCTTCCCTTGCTCCTGGTTCAAGCTGGTGTCTGGGGATTCCCAAG
  GCCCCCAGGGAGGCCCCAGCTGAGCCTGCAGGAGCTGCGGAGGGAGTTCACAGTCAGC
  CTGCATCTCGCCAGGAAGCTGCTCGCCGAGGTTCGGGGCCAGGCCCACCGCTTTGCGG
  AATCTCACCTGCCAGGAGTGAACCTGTACCTCCTGCCCCTGGGAGAGCAGCTCCCTGA
  TGTTTCCCTGACCTTCCAGGCCTGGCGCCGCCTCTCTGACCCGGAGCGTCTCTGCTTC
  ATCTCCACCACGCTTCAGCCCTTCCATGCCCTGCTGGGAGGGCTGGGGACCCAGGGCCGC
  TGGACCAACATGGAGAGGATGCAGCTGTGGGCCATGAGGCTGGACCTCCGCGATCTGC
  AGCGGCACCTCCGCTTCCAGGTGCTGGCTGCAGGATTCAACCTCCCGGAGGAGGAGGA
  GGAGGAAGAGGAGGAGGAGGAGGAGGAGAGGAAGGGGCTGCTCCCAGGGGCACTGGGC
  AGCGCCTTACAGGGCCCGGCCCAGGTGTCCTGGCCCCAGCTCCTCTCCACCTACCGCC
  TGCTGCACTCCTTGGAGCTCGTCTTATCTCGGGCCGTGCGGGAGTTGCTGCTGCTGTC
  CAAGGCTGGGCACTCAGTCTGGCCCTTGGGGTTCCCAACATTGAGCCCCCAGCCCTGATC
  GGTGGCTTCTTAGCCCCCTGCCCCCCACCCTTTAGAACTTTAGGACTGGAGTCTTGGC
  ATCAGGGCAGCCTTCGCATCATCAGCCTTGGACAAGGGAGGGCTCTTCCAGCCCCCTG
  CCCCAGGCCCTACCCAGTAACTGAAAGCCCCTCTGGTCCTCGCCAGCTATTTATTTCT
  TGGATATTTATTTATTGTTTAGGGAGATGATGGTTTATTTATTGTCTTGGGGCCCGAT
  GGTCCTCCTCGGGCCAAGCCCCCATGCTGGGTGCCCAATAAAGCACTCTCATCCATAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145659 unedited
  CCATTACGGCCGGGGACCAAAGAGCTGGGCCCCGCCTGGGCCAGACGGCAGGCGACCTTG
  GCTGGCGGCTCAGCCTGTTGCTGCTTCCCTTGCTCCTGGTTCAAGCTGGTGTCTGGGGAT
  TCCCAAGGCCCCCAGGGAGGCCCCAGCTGAGCCTGCAGGAGCTGCGGAGGGAGTTCACAG
  TCAGCCTGCATCTCGCCAGGAAGCTGCTCGCCGAGGTTCGGGGCCAGGCCCACCGCTTTG
  CGGAATCTCACCTGCCAGGAGTGAACCTGTACCTCCTGCCCCTGGGAGAGCAGCTCCCTG
  ATGTTTCCCTGACCTTCCAGGCCTGGCGCCGCCTCTCTGACCCGGAGCGTCTCTGCTTCA
  TCTCCACCACGCTTCAGCCCTTCCATGCCCTGCTGGGAGGGCTGGGGACCCAGGGCCGCT
  GGACCAACATGGAGAGGATGCAGCTGTGGGCCATGAGGCTGGACCTCCGCGATCTGCAGC
  GGCACCTCCGCTTCCAGGTGCTGGCTGCAGGATTCAACCTCCCGGAGGAGGAGGAGGAGG
  AAGAGGAGGAGGAGG
  
• Restriction Sites: Please inquire
• ACCN: NM_145659
• ORF Size: 732 bp
• Insert Size: 1100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: There are 1 nucleotide differences between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 1 amino acid.

Reference Data

• RefSeq: NM_145659.3, NP_663634.2
• RefSeq Size: 1044
• RefSeq ORF: 732
• Locus ID: 246778
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]