ATG9B (NM_173681) Human Untagged Clone

CAT#: SC306912

ATG9B (untagged)-Human ATG9 autophagy related 9 homolog B (S. cerevisiae) (ATG9B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATG9B
• Synonyms: APG9L2; NOS3AS; SONE
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_173681, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTGAGCCGAATGGGCTGGGGGGGGAGAAGAAGGCGGCTGGGGCGGTGGGGAGATCTGGGGCCCGGAT
  CGGTGCCCCTCCTCCCCATGCCACTGCCACCTCCTCCTCCTCCTTCATGCCGGGGACCTGGGGGAGGGAG
  GATCTCCATCTTCTCTCTGTCCCCTGCCCCTCATACAAGAAGCTCCCCCTCCTCATTTTCCCCTCCCACC
  GCAGGGCCCCCTTGCTCAGTGCTACAGGGGACAGGGGCTTCTCAGTCTTGCCACAGTGCTCTCCCTATCC
  CAGCCACCCCCCCAACACAGGCTCAACCTGCAATGACACCTGCCTCTGCATCTCCCTCCTGGGGATCCCA
  CTCCACCCCACCCCTGGCCCCGGCAACCCCCACTCCCTCACAGCAGTGCCCCCAGGACTCTCCTGGGCTG
  CGGGTAGGCCCTTTGATCCCTGAACAGGATTATGAGCGGCTGGAGGACTGTGACCCTGAGGGGTCCCAAG
  ACTCACCCATCCACGGGGAGGAGCAGCAACCCCTGCTTCATGTCCCTGAAGGGCTCCGAGGCTCCTGGCA
  TCACATCCAGAACCTGGACAGTTTCTTCACCAAGATCTACAGCTACCACCAGCGGAATGGCTTTGCCTGC
  ATCTTGCTGGAGGATGTCTTCCAGCTGGGACAATTTATTTTCATTGTCACCTTCACAACCTTCCTCCTTC
  GATGCGTGGATTACAATGTTCTCTTTGCCAACCAACCAAGTAACCATACCAGACCTGGGCCGTTCCACAG
  CAAAGTGACCCTGTCAGATGCCATCCTACCCTCAGCCCAGTGTGCTGAGAGGATCCGCTCCAGCCCGCTG
  CTGGTCCTCCTCCTGGTCCTGGCTGCCGGCTTCTGGCTGGTCCAACTGCTTCGCTCAGTCTGCAACCTCT
  TCAGCTACTGGGACATCCAGGTGTTTTACAGGGAGGCCCTGCACATCCCCCCGGAGGAGCTGAGCTCGGT
  TCCCTGGGCAGAGGTGCAGTCCCGCCTCTTGGCACTGCAGCGGAGCGGGGGCCTGTGCGTGCAGCCGCGG
  CCCCTGACGGAGCTGGACATCCACCACCGCATCCTGCGCTACACCAACTACCAGGTGGCGCTGGCCAACA
  AAGGCCTGCTGCCGGCCCGCTGCCCGCTGCCCTGGGGAGGCAGTGCGGCTTTCCTCAGCCGCGGCCTGGC
  GCTCAATGTCGACCTGCTGCTCTTCCGCGGTCCCTTCTCGCTCTTCCGCGGGGGCTGGGAGCTGCCGCAC
  GCCTACAAGCGCAGCGACCAGCGGGGCGCCCTAGCAGCGCGCTGGGGGCGCACAGTGCTGCTGCTGGCCG
  CCCTGAACCTGGCGCTGAGCCCGCTGGTGCTGGCCTGGCAGGTTCTGCACGTCTTCTATAGCCACGTGGA
  GCTGCTGCGGCGCGAGCCTGGCGCGCTGGGGGCGCGCGGCTGGTCCCGCCTGGCGCGCTTGCAGCTGCGC
  CACTTCAACGAGCTGCCGCACGAGCTGCGCGCGCGCCTGGCCCGCGCCTACCGCCCCGCCGCCGCCTTCC
  TGCGCACCGCTGCGCCCCCCGCGCCCCTGCGCACGCTGCTGGCCCGCCAGCTCGTTTTCTTCGCGGGTGC
  ACTCTTCGCCGCGCTGCTTGTGCTCACCGTCTACGACGAGGACGTGCTAGCCGTGGAGCACGTGCTCACC
  GCCATGACCGCGCTCGGGGTCACCGCCACCGTCGCCAGGTCTTTCATTCCGGAAGAGCAGTGCCAGGGTC
  GTGCGCCGCAGCTCCTGCTGCAGACAGCCCTGGCCCACATGCACTACCTCCCGGAGGAGCCCGGCCCCGG
  CGGCAGGGACCGCGCCTACCGGCAGATGGCGCAGCTGCTGCAGTACCGAGCGGTCTCCCTCCTGGAGGAG
  CTCCTGTCCCCGCTCCTCACCCCGCTGTTTCTGCTTTTCTGGTTCCGCCCTCGTGCCCTGGAGATTATCG
  ACTTTTTTCATCACTTCACTGTGGATGTGGCTGGGGTTGGGGACATCTGTTCCTTTGCCCTTATGGATGT
  GAAGCGCCACGGACACCCTCAGTGGCTCTCGGCGGGACAGACTGAGGCCTCGCTGTCTCAGCGTGCGGAG
  GACGGCAAGACTGAGCTTTCTTTGATGCGGTTCTCCCTGGCGCATCCACTCTGGCGCCCCCCAGGGCACA
  GCTCTAAGTTTCTTGGGCACCTCTGGGGCCGAGTACAACAAGATGCAGCTGCCTGGGGTGCCACCTCGGC
  TCGCGGCCCCTCCACCCCGGGGGTGCTCAGCAACTGCACCTCGCCCCTGCCTGAGGCCTTCCTGGCCAAC
  CTCTTCGTGCACCCTCTCCTGCCTCCGAGAGATCTGAGCCCGACAGCCCCCTGTCCAGCTGCGGCCACAG
  CCAGCCTCCTTGCCTCCATTTCCCGAATTGCCCAGGACCCCAGCTCTGTGTCCCCAGGAGGCACTGGGGG
  CCAGAAGCTGGCCCAGCTCCCAGAACTTGCTTCTGCCGAGATGAGTCTCCATGTCATCTACCTGCACCAG
  CTTCACCAGCAGCAGCAGCAGCAGGAGCCGTGGGGTGAGGCTGCAGCCTCCATCCTGTCCAGGCCCTGCT
  CCAGCCCCTCACAGCCACCCTCGCCTGATGAGGAGAAGCCATCCTGGTCAAGTGACGGCTCCAGTCCTGC
  CTCTAGCCCCAGACAACAGTGGGGAACCCAGAAGGCCCGGAATCTGTTCCCCGGAGGGTTTCAGGTGACC
  ACAGACACCCAGAAGGAGCCTGACCGGGCCTCTTGCACTGACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_173681
• ORF Size: 2775 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_173681.5, NP_775952.4
• RefSeq Size: 4577
• RefSeq ORF: 2775
• Locus ID: 285973
• Protein Families: Transmembrane
• Gene Summary: This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the supported protein. This transcript contains splicing in the 3' UTR that makes it a candidate for nonsense-mediated mRNA decay (NMD). The protein is thought to be valid, but it may be expressed from alternate transcript variants.