HTR3D (NM_182537) Human Untagged Clone

CAT#: SC307429

HTR3D (untagged)-Human 5-hydroxytryptamine (serotonin) receptor 3 family member D (HTR3D), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HTR3D
• Synonyms: 5HT3D
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_182537 edited
  GCCCTTCACCTGAACAAGGAGAGGGTGGTGGCATGGGACCTGCCTTCCTGGAGTTAATCA
  TCTAGATGAAAGCTGCTATTCCAGGATTCACACCTTCAACTGGTGACATCGTTCCTGTGG
  CTAAATATGCATCAGTGTGGATCAGACACCTGCAGGTCTCATGGCTAGTATGTCAATAGT
  GAAGGCCACATCAAACACAATAAGCCAATGTGGGTGGCCAGCATCTGCAAACTGGACACC
  TTCTATTTCCCCTTCCATGGACAGAGGTGAACGCTCTCCTTCAGCCCTTTCACCTACACA
  GGTGGCCATCAGGCGCAGGTGCAGGCCCAGCCCCTACGTGGTAAACTTTCTGGTGCCCAG
  TGGCATTCTGATTGCCATCGATGCCCTCAGTTTCTACCTGCCACTGGAAAGTGGGAATTG
  TGCCCCATTCAAGATGACTGTTCTGCTGGGCTACAGCGTCTTCCTGCTCATGATGAATGA
  CTTGCTCCCAGCCACTAGCACTTCATCACATGCTTCACTAGTACGTCCTCATCCATCAAG
  AGACCAAAAGCGAGGTGTCTACTTCGCCCTGTGCCTGTCCCTGATGGTGGGCAGCCTGCT
  GGAGACCATCTTCATCACCCACCTGCTGCACGTGGCCACCACCCAGCCCCTACCTCTGCC
  TCGGTGGCTCCACTCCCTGCTGCTGCACTGCACCGGCCAAGGGAGATGCTGTCCCACTGC
  GCCCCAGAAGGGAAATAAGGGCCCGGGTCTCACCCCCACCCACCTGCCCGGTGTGAAGGA
  GCCAGAGGTATCAGCAGGGCAGATGCCAGGCCCTGGGGAGGCAGAGCTGACAGGGGGCTC
  AGAATGGACAAGGGCCCAGCGGGAACACGAGGCCCAGAAGCAGCACTCGGTGGAGCTGTG
  GGTGCAGTTCAGCCACGCGATGGACGCCCTGCTCTTCCACCTCTACCTGCTCTTCATGGC
  CTCCTCCATCATCACCGTTATATGCCTCTGGAACACCTAGGCAGGTGCTCACCTGCCAAC
  TTCAGTCTGGACTTCTTTTTGCCAAAGAACTCCAGAAACCAGTCAGGCTCTCATGTCAGT
  CCAAATTTCAGCCTTGTGGCCCTGTCAACCGCCTCATTTTTAACCCAGTCCTCTGTGTAG
  TTTCAGGCCAGACCTGAATAGTCTCCTATGCCCTCCAAAAGTCGGGTCCTTGCTCCTGCA
  TGCCATCAGCCCCACTCAGCCCTCCCATACCTCCCTGGGATTTAAAGGGC
  
• Restriction Sites: Please inquire
• ACCN: NM_182537
• ORF Size: 840 bp
• Insert Size: 1200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain 2 SNPs compared with NM_182537.2.

Reference Data

• RefSeq: NM_182537.2, NP_872343.2
• RefSeq Size: 1486
• RefSeq ORF: 840
• Locus ID: 200909
• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Gene Summary: The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
  Transcript Variant: This variant (2) differs in the presence and absence of exons at its 5' end, and uses a downstream translational start codon, compared to variant 3. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.