HERV-FRD (ERVFRD-1) (NM_207582) Human Untagged Clone

CAT#: SC308612

ERVFRD (untagged)-Human endogenous retrovirus group FRD, member 1 (ERVFRD-1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERVFRD-1
• Synonyms: envFRD; ERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; UNQ6191
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_207582, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGCCTGCTCCTGCTGGTTCTCATTCTCACGCCTTCACTAGCAGCCTACCGCCATCCTGATTTCCCGT
  TATTGGAAAAAGCTCAGCAACTGCTCCAAAGTACAGGATCCCCTTACTCCACCAATTGCTGGTTATGTAC
  TAGCTCTTCCACTGAAACACCAGGGACAGCTTATCCAGCCTCGCCCAGAGAATGGACAAGCATAGAGGCG
  GAATTACATATTTCCTATCGATGGGACCCTAATCTGAAAGGACTGATGAGGCCTGCAAATAGTCTTCTTT
  CAACAGTAAAGCAAGATTTCCCTGATATCCGCCAGAAACCTCCCATTTTCGGACCCATCTTTACTAATAT
  CAACCTAATGGGAATAGCCCCTATTTGTGTTATGGCCAAAAGGAAAAATGGAACAAATGTAGGCACTCTT
  CCAAGTACAGTCTGTAATGTTACTTTCACTGTAGATTCTAACCAACAGACTTACCAAACATACACCCACA
  ACCAATTCCGCCATCAACCAAGATTCCCCAAACCTCCAAATATTACTTTTCCTCAGGGAACTTTGCTAGA
  TAAATCCAGCCGGTTTTGCCAGGGACGCCCAAGCTCATGCAGTACTCGAAACTTCTGGTTCCGGCCTGCT
  GATTATAACCAATGTCTGCAAATTTCCAACCTCAGCTCTACAGCGGAATGGGTTCTATTGGACCAAACTC
  GAAATTCTCTTTTTTGGGAAAATAAAACCAAGGGAGCTAACCAGAGCCAAACACCCTGCGTCCAAGTCTT
  AGCAGGCATGACTATAGCCACCAGCTACCTGGGCATATCAGCAGTCTCAGAATTTTTTGGAACCTCCCTC
  ACCCCCTTATTTCATTTCCATATCTCTACATGCCTTAAAACTCAAGGAGCCTTTTATATTTGTGGCCAGT
  CGATTCACCAATGCCTCCCCAGTAACTGGACTGGAACTTGTACCATAGGCTATGTAACCCCAGACATCTT
  CATAGCCCCTGGCAATCTCTCTCTTCCAATACCAATCTATGGGAATTCCCCGTTGCCCAGGGTGAGGAGG
  GCAATCCATTTCATTCCCCTTCTCGCGGGACTCGGCATTCTAGCTGGTACGGGAACCGGAATTGCTGGAA
  TCACAAAAGCTTCCCTCACCTATAGCCAGCTCTCAAAGGAAATAGCCAACAACATTGACACCATGGCTAA
  AGCCTTAACGACCATGCAAGAACAAATCGACTCTTTAGCAGCCGTAGTCCTTCAAAATCGTCGAGGACTA
  GACATGTTAACGGCAGCACAGGGAGGAATTTGTTTGGCCTTAGATGAAAAATGTTGCTTTTGGGTAAATC
  AATCAGGAAAAGTACAAGACAACATCAGACAACTCCTAAATCAAGCCTCCAGTTTACGGGAACGAGCCAC
  TCAGGGTTGGTTAAATTGGGAAGGAACTTGGAAATGGTTCTCTTGGGTTCTTCCCCTTACAGGCCCACTT
  GTTAGTCTCCTACTTTTGCTCCTTTTTGGTCCATGTCTCCTAAATCTAATAACCCAATTTGTCTCCTCTC
  GCCTTCAGGCCATAAAGCTCCAGACGAATCTCAGTGCAGGACGCCATCCTCGCAATATTCAAGAGTCACC
  CTTCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_207582
• ORF Size: 1617 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_207582.2, NP_997465.1
• RefSeq Size: 3318
• RefSeq ORF: 1617
• Locus ID: 405754
• Protein Families: Transmembrane
• Gene Summary: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Jun 2012]