NALP1 (NLRP1) (NM_033007) Human Untagged Clone

CAT#: SC309631

NLRP1 (untagged)-Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 4


  "NM_033007" in other vectors (4)

Reconstitution Protocol

USD 2,840.00

7 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NLRP1
Synonyms AIADK; CARD7; CIDED; CLR17.1; DEFCAP; DEFCAP-L/S; MSPC; NAC; NALP1; PP1044; SLEV1; VAMAS1
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_033007, the custom clone sequence may differ by one or more nucleotides
ATGGCTGGCGGAGCCTGGGGCCGCCTGGCCTGTTACTTGGAGTTCCTGAAGAAGGAGGAG
CTGAAGGAGTTCCAGCTTCTGCTCGCCAATAAAGCGCACTCCAGGAGCTCTTCGGGTGAG
ACACCCGCTCAGCCAGAGAAGACGAGTGGCATGGAGGTGGCCTCGTACCTGGTGGCTCAG
TATGGGGAGCAGCGGGCCTGGGACCTAGCCCTCCATACCTGGGAGCAGATGGGGCTGAGG
TCACTGTGCGCCCAAGCCCAGGAAGGGGCAGGCCACTCTCCCTCATTCCCCTACAGCCCA
AGTGAACCCCACCTGGGGTCTCCCAGCCAACCCACCTCCACCGCAGTGCTAATGCCCTGG
ATCCATGAATTGCCGGCGGGGTGCACCCAGGGCTCAGAGAGAAGGGTTTTGAGACAGCTG
CCTGACACATCTGGACGCCGCTGGAGAGAAATCTCTGCCTCACTCCTCTACCAAGCTCTT
CCAAGCTCCCCAGACCATGAGTCTCCAAGCCAGGAGTCACCCAACGCCCCCACATCCACA
GCAGTGCTGGGGAGCTGGGGATCCCCACCTCAGCCCAGCCTAGCACCCAGAGAGCAGGAG
GCTCCTGGGACCCAATGGCCTCTGGATGAAACGTCAGGAATTTACTACACAGAAATCAGA
GAAAGAGAGAGAGAGAAATCAGAGAAAGGCAGGCCCCCATGGGCAGCGGTGGTAGGAACG
CCCCCACAGGCGCACACCAGCCTACAGCCCCACCACCACCCATGGGAGCCTTCTGTGAGA
GAGAGCCTCTGTTCCACATGGCCCTGGAAAAATGAGGATTTTAACCAAAAATTCACACAG
CTGCTACTTCTACAAAGACCTCACCCCAGAAGCCAAGATCCCCTGGTCAAGAGAAGCTGG
CCTGATTATGTGGAGGAGAATCGAGGACATTTAATTGAGATCAGAGACTTATTTGGCCCA
GGCCTGGATACCCAAGAACCTCGCATAGTCATACTGCAGGGGGCTGCTGGAATTGGGAAG
TCAACACTGGCCAGGCAGGTGAAGGAAGCCTGGGGGAGAGGCCAGCTGTATGGGGACCGC
TTCCAGCATGTCTTCTACTTCAGCTGCAGAGAGCTGGCCCAGTCCAAGGTGGTGAGTCTC
GCTGAGCTCATCGGAAAAGATGGGACAGCCACTCCGGCTCCCATTAGACAGATCCTGTCT
AGGCCAGAGCGGCTGCTCTTCATCCTCGATGGTGTAGATGAGCCAGGATGGGTCTTGCAG
GAGCCGAGTTCTGAGCTCTGTCTGCACTGGAGCCAGCCACAGCCGGCGGATGCACTGCTG
GGCAGTTTGCTGGGGAAAACTATACTTCCCGAGGCATCCTTCCTGATCACGGCTCGGACC
ACAGCTCTGCAGAACCTCATTCCTTCTTTGGAGCAGGCACGTTGGGTAGAGGTCCTGGGG
TTCTCTGAGTCCAGCAGGAAGGAATATTTCTACAGATATTTCACAGATGAAAGGCAAGCA
ATTAGAGCCTTTAGGTTGGTCAAATCAAACAAAGAGCTCTGGGCCCTGTGTCTTGTGCCC
TGGGTGTCCTGGCTGGCCTGCACTTGCCTGATGCAGCAGATGAAGCGGAAGGAAAAACTC
ACACTGACTTCCAAGACCACCACAACCCTCTGTCTACATTACCTTGCCCAGGCTCTCCAA
GCTCAGCCATTGGGACCCCAGCTCAGAGACCTCTGCTCTCTGGCTGCTGAGGGCATCTGG
CAAAAAAAGACCCTTTTCAGTCCAGATGACCTCAGGAAGCATGGGTTAGATGGGGCCATC
ATCTCCACCTTCTTGAAGATGGGTATTCTTCAAGAGCACCCCATCCCTCTGAGCTACAGC
TTCATTCACCTCTGTTTCCAAGAGTTCTTTGCAGCAATGTCCTATGTCTTGGAGGATGAG
AAGGGGAGAGGTAAACATTCTAATTGCATCATAGATTTGGAAAAGACGCTAGAAGCATAT
GGAATACATGGCCTGTTTGGGGCATCAACCACACGTTTCCTATTGGGCCTGTTAAGTGAT
GAGGGGGAGAGAGAGATGGAGAACATCTTTCACTGCCGGCTGTCTCAGGGGAGGAACCTG
ATGCAGTGGGTCCCGTCCCTGCAGCTGCTGCTGCAGCCACACTCTCTGGAGTCCCTCCAC
TGCTTGTACGAGACTCGGAACAAAACGTTCCTGACACAAGTGATGGCCCATTTCGAAGAA
ATGGGCATGTGTGTAGAAACAGACATGGAGCTCTTAGTGTGCACTTTCTGCATTAAATTC
AGCCGCCACGTGAAGAAGCTTCAGCTGATTGAGGGCAGGCAGCACAGATCAACATGGAGC
CCCACCATGGTAGTCCTGTTCAGGTGGGTCCCAGTCACAGATGCCTATTGGCAGATTCTC
TTCTCCGTCCTCAAGGTCACCAGAAACCTGAAGGAGCTGGACCTAAGTGGAAACTCGCTG
AGCCACTCTGCAGTGAAGAGTCTTTGTAAGACCCTGAGACGCCCTCGCTGCCTCCTGGAG
ACCCTGCGGTTGGCTGGCTGTGGCCTCACAGCTGAGGACTGCAAGGACCTTGCCTTTGGG
CTGAGAGCCAACCAGACCCTGACCGAGCTGGACCTGAGCTTCAATGTGCTCACGGATGCT
GGAGCCAAACACCTTTGCCAGAGACTGAGACAGCCGAGCTGCAAGCTACAGCGACTGCAG
CTGGTCAGCTGTGGCCTCACGTCTGACTGCTGCCAGGACCTGGCCTCTGTGCTTAGTGCC
AGCCCCAGCCTGAAGGAGCTAGACCTGCAGCAGAACAACCTGGATGACGTTGGCGTGCGA
CTGCTCTGTGAGGGGCTCAGGCATCCTGCCTGCAAACTCATACGCCTGGGGAAACCAAGT
GTGATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTC
AAGCGGCAGAGACTCGGATCAGAGAGGGCGGCTTCCCATGTTGCTCAGGCTAATCTCAAA
CTCCTGGACGTGAGCAAGATCTTCCCAATTGCTGAGATTGCAGAGGAAAGCTCCCCAGAG
GTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACG
AAGCCTTTGGGGACTGACGATGACTTCTGGGGCCCCACGGGGCCTGTGGCTACTGAGGTA
GTTGACAAAGAAAAGAACTTGTACCGAGTTCACTTCCCTGTAGCTGGCTCCTACCGCTGG
CCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGT
GTGTGGGACCAGTTCCTGGGTGAGATCAACCCACAGCACAGCTGGATGGTGGCAGGGCCT
CTGCTGGACATCAAGGCTGAGCCTGGAGCTGTGGAAGCTGTGCACCTCCCTCACTTTGTG
GCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAG
GGGATGCTCCTGGAGAAGCCAGCCAGGGTGGAGCTGCATCACATAGTTCTGGAAAACCCC
AGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATGATCCATAATGCCCTGCGCTTCATTCCC
GTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTC
TACCTGATCCCAAGTGACTGCTCCATTCGGAAGGAACTGGAGCTCTGCTATCGAAGCCCT
GGAGAAGACCAGCTGTTCTCGGAGTTCTACGTTGGCCACTTGGGATCAGGGATCAGGCTG
CAAGTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAGGCCTTGGTGAAACCAGGAGAT
CTCATGCCTGCAACTACTCTGATCCCTCCAGCCCGCATAGCCGTACCTTCACCTCTGGAT
GCCCCGCAGTTGCTGCACTTTGTGGACCAGTATCGAGAGCAGCTGATAGCCCGAGTGACA
TCGGTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTGCTGAGCCAGGAGCAGTACGAG
AGGGTGCTGGCTGAGAACACGAGGCCCAGCCAGATGCGGAAGCTGTTCAGCTTGAGCCAG
TCCTGGGACCGGAAGTGCAAAGATGGACTCTACCAAGCCCTGAAGGAGACCCATCCTCAC
CTCATTATGGAACTCTGGGAGAAGGGCAGCAAAAAGGGACTCCTGCCACTCAGCAGCTGA
Restriction Sites Please inquire     
ACCN NM_033007
ORF Size 4200 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_033007.2, NP_127500.1
RefSeq Size 5395
RefSeq ORF 4200
Locus ID 22861
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway
Gene Summary This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (4) lacks two in-frame exons in the coding region, as compared to variant 1. The encoded isoform 4 is missing two internal segments, as compared to isoform 1.

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