PCDHGB3 (NM_018924) Human Untagged Clone

CAT#: SC309668

PCDHGB3 (untagged)-Human protocadherin gamma subfamily B, 3 (PCDHGB3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGB3
• Synonyms: PCDH-GAMMA-B3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018924, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAAATAGCTCCGGATGGAGGGGCCCAGCAGGGCAGAGGCGAATGCTATTTCTCTTCCTGCTCTCTT
  TGTTAGACCAGGCTCTCTCCGAACCGATCCGCTACGCTATTCCCGAGGAGCTGGACAGGGGCTCGCTGGT
  AGGGAACCTCGCCAAGGACCTGGGGTTTGGCGTGGGGGATTTACCTACTAGGAACCTGCGGGTTATTGCA
  GAGAAGAAATTCTTTACCGTGAGCCCCGAAAATGGGAACTTACTTGTGAGCGACCGTATAGACCGAGAGG
  AGATTTGTGGCAAGAAGTCGACGTGTGTTCTGGAATTTGAAATGGTTGCTGAAAAGCCTTTAAACTTTTT
  TCATGTAACTGTGCTGATCCAGGATATTAACGACAACCCACCGACCTTTAGCCAAAATATCACTGAGCTG
  GAAATCAGCGAACTGGCTCTCACTGGAGCCACATTTGCCCTGGAATCTGCGCAAGATCCTGATGTAGGTG
  TCAATTCGCTGCAGCAGTACTACCTCAGCCCTGATCCGCACTTCTCTTTGATTCAGAAGGAGAACCTGGA
  TGGCAGTAGGTACCCAGAGCTAGTACTGAAAGCACCCCTGGACAGGGAAGAGCAGCCACATCACCACCTG
  GTCCTCACAGCTGTGGATGGGGGCGAGCCCTCCAGAAGCTGTACCACCCAGATCAGGGTAATTGTCGCAG
  ATGCAAATGATAACCCCCCAGTATTTACTCAGGACATGTACAGGGTCAATGTTGCAGAGAACCTGCCCGC
  TGGCTCCTCCGTATTAAAAGTGATGGCCATTGACATGGATGAGGGCATCAATGCCGAAATCATCTATGCC
  TTCATCAATATTGGCAAGGAAGTGAGACAACTGTTCAAGCTGGACAGTAAAACGGGGGAACTCACCACTA
  TTGGAGAACTGGACTTTGAAGAGAGAGATAGCTACACAATTGGGGTGGAAGCAAAGGATGGTGGACATCA
  CACTGCATATTGTAAAGTACAGATAGATATTTCAGATGAAAATGACAATGCCCCGGAGATAACCCTGGCT
  TCTGAATCCCAACATATACAAGAAGATGCTGAGCTGGGGACTGCCGTTGCCCTGATCAAAACACATGATC
  TAGATTCTGGATTTAATGGAGAAATCCTATGCCAACTAAAAGGAAACTTCCCCTTTAAAATCGTTCAAGA
  TACCAAAAACACATACAGGTTGGTGACAGATGGAGCCCTGGACCGGGAGCAGATCCCAGAATACAATGTG
  ACGATCACAGCTACCGACAAAGGCAATCCACCGCTCTCCTCCAGCAAGACCATCACTCTGCACATCCTTG
  ATGTCAACGACAACGTTCCCGTTTTCCACCAGGCCTCCTACACCGTGCATGTAGCTGAGAACAATCCGCC
  TGGAGCCTCCATTGCGCATGTCAGAGCCTCGGATCCCGACTTGGGACCTAATGGCCTTGTCTCCTACTAC
  ATCGTGGCCAGTGACCTGGAGCCGCGGGAGCTGTCGTCCTACGTGTCCGTGAGCGCGCGGAGCGGGGTGG
  TGTTCGCGCAGCGAGCCTTCGACCACGAGCAGCTGCGTGCCTTCGAGCTCACTCTGCAGGCCCGCGACCA
  GGGCTCGCCTACGCTCAGCGCCAACGTGAGCCTGCGCGTGTTGGTGGACGACCGCAACGACAATGCACCG
  CTGGTGCTGTACCCAGCTCTGGGGCCCGAAGGCTCTGCGCTCTTCGATATGGTGCCGCGCTCTGCAGAGC
  CTGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGCAGACTCGGGATACAACGCCTGGCTGTCCTACCA
  CATTGTGCAGGCCAGCGAGCCCGGGCTGTTCAGCCTGGGCCTGCGCACGGGTGAGGTGCGCACGGCGCGT
  ACCTTGGGCGACAGGGAGGCCGCCCGCCAGCGCCTGCTGGTCACTGTGCGTGATGGAGGACAGCAGCCTC
  TTTCAGCCACCGTCATGCTGCACCTAATCTTCGCAGATAGCTTGCAAGAGATACAACCTGACCTTAGCGA
  CCGCCCCACTCCCTCTGACCCTCAGGCGGAGCTACAGTTTCACCTAGTAGTGGCGTTGGCCTTGATCTCA
  GTGCTCTTCCTCCTCGCGGTGATTCTGGCAATCTCCCTGCGCCTGCGATGCTCCTCCAGACCCGCCACTG
  AGGGCTACTTTCAGCCTGGTGTCTGCTTCAAGACTGTACCTGGAGTTCTCCCCACCTACAGCGAAAGGAC
  TTTGCCTTATTCCTACAATCCGTGTGCTGCCTCACATTCCTCAAACACCGAGTTTAAATTTCTCAATATA
  AAGGCTGAAAATGCTGCACCACAAGATCTTCTATGTGATGAAGCCTCTTGGTTTGAAAGTAATGACAATC
  CAGAAATGCCTTCTAATTCAGGCAATTTGCAAAAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCA
  GGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAACAACCAGTTT
  GACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGATGGGAGCTCCACCCTGG
  GAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCCCAGTTCACCCTGCAGCACGTGCCCGA
  CTACCGCCAGAATGTCTACATCCCAGGCAGCAATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGC
  AAGGCCCCAGCAGGTGGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_018924
• ORF Size: 2790 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018924.4, NP_061747.2
• RefSeq Size: 4727
• RefSeq ORF: 2790
• Locus ID: 56102
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript, which includes the constant region exons, and encodes the longer isoform (1).