PCDHA1 (NM_031410) Human Untagged Clone

CAT#: SC309677

PCDHA1 (untagged)-Human protocadherin alpha 1 (PCDHA1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA1
• Synonyms: PCDH-ALPHA1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031410, the custom clone sequence may differ by one or more nucleotides
  ATGGTGTTTTCTAGGAGAGGGGGCCTGGGAGCCCGGGATCTGCTTCTTTGGCTTCTGCTC
  CTCGCAGCCTGGGAGGTGGGGAGCGGCCAGCTCCACTACTCGATCCCGGAGGAAGCCAAA
  CACGGCACCTTCGTTGGCCGCGTTGCTCAGGACCTGGGACTGGAGCTGGCGGAGCTGGTG
  CCTCGCCTGTTCCGGGTGGCGTCCAAAACACACAGGGACCTTCTGGAGGTAAATCTGCAG
  AATGGCATTTTGTTTGTGAATTCTCGGATCGATCGCGAGGAGCTGTGCCAGTGGAGCGCG
  GAGTGCAGCATCCACCTGGAGTTGATCGCCGACAGGCCGCTGCAGGTTTTCCATGTGGAG
  GTGAAGGTGAAAGACATTAACGATAATCCACCCGTCTTCAGGGGCAGAGAACAAATAATA
  TTTATTCCTGAATCTAGACTCCTGAATTCGCGTTTTCCGATAGAAGGAGCTGCTGATGCA
  GACATTGGTGCTAACGCTCTTCTAACGTACACGCTCAGCCCGAGTGATTATTTCTCTTTG
  GATGTAGAGGCAAGTGATGAACTGAGTAAATCTCTTTGGCTTGAATTGAGAAAATATTTG
  GATAGAGAAGAAACACCAGAACTTCACTTATTACTGACTGCCACTGATGGGGGCAAACCG
  GAGCTGCAAGGTACAGTTGAGCTGCTGATCACCGTCCTCGACGTTAATGATAACGCCCCA
  CTGTTTGACCAGGCCGTATACAGAGTCCACTTGTTAGAGACTACAGCAAATGGAACATTA
  GTGACCACATTAAATGCCTCTGATGCTGACGAAGGTGTAAATGGTGAAGTCGTCTTTTCC
  TTTGACAGTGGTATTTCTCGTGACATTCAAGAAAAATTCAAAGTTGATTCCAGCTCAGGA
  GAAATTAGGTTAATTGATAAACTGGATTATGAAGAAACAAAATCCTACGAAATTCAAGTA
  AAGGCAGTTGATAAAGGAAGTCCTCCGATGTCAAATCACTGTAAGGTTTTGGTGAAAGTG
  CTGGATGTAAATGATAATGCTCCAGAACTGGCGGTCACTTCATTGTATTTGCCTATCAGA
  GAGGACGCTCCACTCAGCACCGTCATCGCCCTCATCACCGTGTCTGACCGTGACTCAGGT
  GCCAACGGGCAGGTGACTTGCTCCTTAATGCCCCACGTCCCCTTCAAGCTGGTGTCCACC
  TTCAAGAATTACTACTCGTTGGTGTTGGACAGCGCCCTGGATCGCGAGAGCCTGTCGGTC
  TATGAGCTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTTCGCTGTGGGCCACGGCCAGG
  GTGTCCGTGGAGGTGGCCGACGTGAATGACAACGCGCCTGCGTTCGCGCAGCCCGAGTAC
  ACAGTATTCGTGAAGGAGAACAACCCGCCGGGCTGCCACATCTTCACGGTGTCTGCGCGG
  GACGCGGACGCGCAGGAGAACGCGCTGGTGTCCTATTCGCTGGTGGAACGGCGGGTGGGC
  GAGCGCGCGCTGTCGAACTACGTGTCAGTGCACGCGGAGAGCGGCAAGGTGTACGCACTG
  CAGCCCCTGGACCACGAGGAGCTGGAGCTGCTGCAGTTCCAGGTGAGCGCGCGGGATGCG
  GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
  AACGCGCCGGCGCTGCTGGCGCCTCGAGTGGGTGGCACTATTGGTGCAGTCAGTGAGCTG
  GTGCCGCGATTGGTGGGTGCGGGTCATGTGGTGGCGAAGGTGCGCGCAGTGGACGCCGAC
  TCGGGCTACAACGCGTGGCTGTCCTATGAACTGCAGCCGGCAGCAGGCGGCGCGCGCATC
  CCGTTCCGCGTGGGGCTGTACACGGGCGAGATCAGCACGACTCGTGTCCTGGACGAGGCT
  GACTTGTCGCGCTACCGCCTTCTGGTGCTAGTGAAGGATCACGGTGAGCCGGCGCTGACA
  GCCACGGCCACTGTGCTTGTATCTCTGGTGGAGAGCGGCCAGGCGCCAAAGGCGTCTTCG
  CGGGCGTCGGTGGGTGTCGCGGGCCCAGAGGCGGCGCTGGTGGATGTCAACGTGTACCTG
  ATCATCGCCATCTGCGCGGTGTCCAGCCTGCTGGTGCTCACACTGCTGCTGTACACGGCG
  CTGCGGTGCTCAGTGCCGCCCACTGAGGGTGCGTATGTGCCGGGCAAGCCCACTCTGGTG
  TGCTCCAGCGCGTTGGGGAGCTGGTCGAACTCACAGCAGAGGCGGCAGAGGGTGTGCTCT
  AGCGAGGGCCCACCCAAGACCGACCTCATGGCCTTCAGCCCAGGCCTATCTCCAAGTCTT
  AACACGTCAGAAAGAAATGAACAACCAGAAGCAAATTTGGATCTTTCTGGTAATGTAAGT
  CCAACTTTCGAGTTTTGGCTTTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_031410
• ORF Size: 2424 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031410.1, NP_113598.1
• RefSeq Size: 2571
• RefSeq ORF: 2424
• Locus ID: 56147
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.