PCDHA1 (NM_018900) Human Untagged Clone

CAT#: SC309733

PCDHA1 (untagged)-Human protocadherin alpha 1 (PCDHA1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA1
• Synonyms: PCDH-ALPHA1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018900, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTGTTTTCTAGGAGAGGGGGCCTGGGAGCCCGGGATCTGCTTCTTTGGCTTCTGCTCCTCGCAGCCT
  GGGAGGTGGGGAGCGGCCAGCTCCACTACTCGATCCCGGAGGAAGCCAAACACGGCACCTTCGTTGGCCG
  CGTTGCTCAGGACCTGGGACTGGAGCTGGCGGAGCTGGTGCCTCGCCTGTTCCGGGTGGCGTCCAAAACA
  CACAGGGACCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAATTCTCGGATCGATCGCGAGG
  AGCTGTGCCAGTGGAGCGCGGAGTGCAGCATCCACCTGGAGTTGATCGCCGACAGGCCGCTGCAGGTTTT
  CCATGTGGAGGTGAAGGTGAAAGACATTAACGATAATCCACCCGTCTTCAGGGGCAGAGAACAAATAATA
  TTTATTCCTGAATCTAGACTCCTGAATTCGCGTTTTCCGATAGAAGGAGCTGCTGATGCAGACATTGGTG
  CTAACGCTCTTCTAACGTACACGCTCAGCCCGAGTGATTATTTCTCTTTGGATGTAGAGGCAAGTGATGA
  ACTGAGTAAATCTCTTTGGCTTGAATTGAGAAAATATTTGGATAGAGAAGAAACACCAGAACTTCACTTA
  TTACTGACTGCCACTGATGGGGGCAAACCGGAGCTGCAAGGTACAGTTGAGCTGCTGATCACCGTCCTCG
  ACGTTAATGATAACGCCCCACTGTTTGACCAGGCCGTATACAGAGTCCACTTGTTAGAGACTACAGCAAA
  TGGAACATTAGTGACCACATTAAATGCCTCTGATGCTGACGAAGGTGTAAATGGTGAAGTCGTCTTTTCC
  TTTGACAGTGGTATTTCTCGTGACATTCAAGAAAAATTCAAAGTTGATTCCAGCTCAGGAGAAATTAGGT
  TAATTGATAAACTGGATTATGAAGAAACAAAATCCTACGAAATTCAAGTAAAGGCAGTTGATAAAGGAAG
  TCCTCCGATGTCAAATCACTGTAAGGTTTTGGTGAAAGTGCTGGATGTAAATGATAATGCTCCAGAACTG
  GCGGTCACTTCATTGTATTTGCCTATCAGAGAGGACGCTCCACTCAGCACCGTCATCGCCCTCATCACCG
  TGTCTGACCGTGACTCAGGTGCCAACGGGCAGGTGACTTGCTCCTTAATGCCCCACGTCCCCTTCAAGCT
  GGTGTCCACCTTCAAGAATTACTACTCGTTGGTGTTGGACAGCGCCCTGGATCGCGAGAGCCTGTCGGTC
  TATGAGCTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTTCGCTGTGGGCCACGGCCAGGGTGTCCGTGG
  AGGTGGCCGACGTGAATGACAACGCGCCTGCGTTCGCGCAGCCCGAGTACACAGTATTCGTGAAGGAGAA
  CAACCCGCCGGGCTGCCACATCTTCACGGTGTCTGCGCGGGACGCGGACGCGCAGGAGAACGCGCTGGTG
  TCCTATTCGCTGGTGGAACGGCGGGTGGGCGAGCGCGCGCTGTCGAACTACGTGTCAGTGCACGCGGAGA
  GCGGCAAGGTGTACGCACTGCAGCCCCTGGACCACGAGGAGCTGGAGCTGCTGCAGTTCCAGGTGAGCGC
  GCGGGATGCGGGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
  AACGCGCCGGCGCTGCTGGCGCCTCGAGTGGGTGGCACTATTGGTGCAGTCAGTGAGCTGGTGCCGCGAT
  TGGTGGGTGCGGGTCATGTGGTGGCGAAGGTGCGCGCAGTGGACGCCGACTCGGGCTACAACGCGTGGCT
  GTCCTATGAACTGCAGCCGGCAGCAGGCGGCGCGCGCATCCCGTTCCGCGTGGGGCTGTACACGGGCGAG
  ATCAGCACGACTCGTGTCCTGGACGAGGCTGACTTGTCGCGCTACCGCCTTCTGGTGCTAGTGAAGGATC
  ACGGTGAGCCGGCGCTGACAGCCACGGCCACTGTGCTTGTATCTCTGGTGGAGAGCGGCCAGGCGCCAAA
  GGCGTCTTCGCGGGCGTCGGTGGGTGTCGCGGGCCCAGAGGCGGCGCTGGTGGATGTCAACGTGTACCTG
  ATCATCGCCATCTGCGCGGTGTCCAGCCTGCTGGTGCTCACACTGCTGCTGTACACGGCGCTGCGGTGCT
  CAGTGCCGCCCACTGAGGGTGCGTATGTGCCGGGCAAGCCCACTCTGGTGTGCTCCAGCGCGTTGGGGAG
  CTGGTCGAACTCACAGCAGAGGCGGCAGAGGGTGTGCTCTAGCGAGGGCCCACCCAAGACCGACCTCATG
  GCCTTCAGCCCAGGCCTATCTCCAAGTCTTAACACGTCAGAAAGAAATGAACAACCAGAAGCAAATTTGG
  ATCTTTCTGGTAATCCACGACAGCCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCA
  CAGCTCTGTGCACCTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCA
  ACAGTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTCAACA
  GCAACAGCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAA
  ATTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAAATTGACAAA
  AGTGACTTCATAACCTTCGGCAAAAAGGAGGAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGA
  CCCAGGAGAAAAAAGAGAAAGGGAACAGCACGACTGACAACAGTGACCAGTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_018900
• ORF Size: 2853 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018900.3, NP_061723.1
• RefSeq Size: 5415
• RefSeq ORF: 2853
• Locus ID: 56147
• Domains: CA
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1).