PCDHA11 (NM_031861) Human Untagged Clone

CAT#: SC310099

PCDHA11 (untagged)-Human protocadherin alpha 11 (PCDHA11), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA11
• Synonyms: CNR7; CNRN7; CNRS7; CRNR7; PCDH-ALPHA11
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031861, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTTGGTTTTCAGAGAAGGGGATTGGGCACCCCACGACTACAGCTCTGGCTTCTCCTCCTCGAATTCT
  GGGAGGTGGGGAGCGGCCAGCTCCACTACTCCGTCTCGGAGGAGGCCAAACACGGCACCTTCGTGGGCCG
  CATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTGCAGCGCCTGTTCCGGGTGGCGTCCAAAACA
  CATGGGGACCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGG
  AGCTGTGCGGGCAGAGCGCGGAGTGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTT
  CCATGTGAACGTGGAGGTGAAGGACATTAACGACAACCCGCCGGTGTTCTCGCTCAGAGAACAAAAGCTG
  CTGATTGCGGAATCTAAGCAATCGGACTCGCGTTTTCCACTAGAGGGAGCTTCTGATGCTGACATTGAAG
  AGAATGCTCTATTGACCTACAGGCTAAGTAAAAATGAGTATTTTTCTTTAGATTCACCAACAAATGGTAA
  GCAGATTAAAAGACTGTCACTTATTTTAAAGAAGTCTCTGGATAGAGAGAAAACTCCGGAACTTAATTTG
  CTGCTAACAGCTACAGACGGGGGAAAACCAGAGCTTACTGGCACCGTTCGGCTGTTAGTCCAAGTCTTGG
  ATGTCAACGACAATGATCCAGAGTTTGATAAATCAGAATATAAGGTGAGCCTTATGGAAAATGCTGCTAA
  AGAAACTCTTGTGCTCAAACTAAACGCCACAGACCGAGACGAAGGAGTCAATGGAGAGGTAACATACTCC
  TTAATGTCAATTAAGCCCAATGGAAGACACTTATTTACACTAGATCAAAATAATGGAGAAGTGAGGGTCA
  ATGGAACTTTAGATTATGAAGAAAACAAGTTTTATAAAATTGAAGTACAGGCTACAGATAAGGGGACTCC
  CCCAATGGCAGGTCACTGTACAGTCTGGGTGGAAATCTTGGACACCAACGATAACTCTCCTGAAGTCGCC
  GTGACTTCCTTGTCCCTCCCAGTACGAGAGGACGCTCAGCCCAGCACGGTCATTGCCCTGATCAGCGTGT
  CTGACCGTGACTCAGGTGTCAACGGACAGGTGACCTGCTCGCTGACGCCCCACGTTCCCTTCAAGCTGGT
  GTCCACCTTCAAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAACGTGTGGGCCTAT
  GAACTGGTGGTGACTGCGCGGGATGGGGGTTCGCCTTCTCTGTGGGCCACGGCCAGGGTATCCGTGGAGG
  TGGCCGACGTGAACGACAATGCGCCTGCGTTCGCACAGCCCGAGTACACCGTGTTCGTGAAGGAGAACAA
  CCCACCAGGCTGCCACATCTTCACAGTGTCGGCGCGGGACGCGGACGCGCAGGAGAACGCGCTGGTGTCC
  TACTCGCTGGTGGAGCGGCGGTTGGGCGACCGCGCGCTGTCGAGCTACGTGTCGGTGCACGCGGAGAGCG
  GCAAGGTGTACGCGCTGCAGCCGTTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGGTGAGCGCGCG
  CGATGCGGGCGTGCCGCCTCTGAGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGACAAC
  GCGCCGGCACTGCTGGCGACTCAGGCTGGCAGCGCGGGAGGCGCAGTTAACAAGCTAGTACCGCGGTCGG
  TGGGTGCGGGCCACGTGGTGGCGAAGGTGCGCGCAGTGGATGCGGACTCAGGCTACAACGCGTGGCTTTC
  ATATGAATTGCAGCCGGCGGCGGGCGGCTCGCGCATCCCGTTCCGCGTGGGGCTGTACACGGGCGAGATA
  AGCACAACGCGTGCCCTGGACGAGGCAGACTCGCCGCGCCACCGACTTCTAGTACTGGTGAAGGATCACG
  GTGAGCCGGCGCTGACGGCCACGGCCACCGTGCTGGTGTCGTTGGTGGAGAGCGGACAGGCGCCAAAGGC
  CTCTTCCCGGACTTTGGCGGGCGCCGCGAGCCCAGAGGCTGCGCTGGTGGATGTCAACGTGTACCTGATC
  ATCGCCATCTGCGTGGTGTCCAGCCTCCTGGTACTCACGCTGCTGCTGTATACGGCGCTGTGGTGGTCGG
  CAACGCCCACTGAGGGCGCGTGCGCGCCGGGGAAGCCCACGCTGGTGTGCTCCCGCGCGGTGGGGAGCTG
  GTCATACTCGCAGCAGAGGCGGCAGAGGGTGTGCTCTGAGGAGGGCCCACCTAAGACGGACCTCATGGCC
  TTCAGCCCCAGTCTTCCTCTAGGTCTGAATAAAGAGGAGGAAGGGGAAAGACAGGAGCCAGGGTCAAATC
  ACCCCGGACAGGTGAGTTTTCTACAGATTCCACCTATCAGGAAGTGTATGTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_031861
• ORF Size: 2433 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031861.2, NP_114067.1
• RefSeq Size: 4088
• RefSeq ORF: 2433
• Locus ID: 56138
• Domains: CA
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2).