SPIRE1 (NM_020148) Human Untagged Clone

CAT#: SC311128

SPIRE1 (untagged)-Human spire homolog 1 (Drosophila) (SPIRE1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPIRE1
• Synonyms: Spir-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020148, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCAGGCGGCTGGCCCGGCGGGCGGCGGGGAGCCGCGGACTGAGGCAGTGGGCGGCGAGGGGCCGC
  GGGAGCCCGGGGCAGCCGGCGGCGCGGCCGGGGGCTCCCGGGACGCGCTGAGCCTGGAGGAGATCCTGCG
  GCTGTACAACCAGCCCATCAACGAGGAGCAGGCGTGGGCCGTGTGCTACCAGTGCTGCGGTTCCCTGCGC
  GCCGCCGCCCGCCGCCGCCAGCCCCGCCACCGTGTGCGCTCGGCCGCGCAGATCCGCGTCTGGAGGGACG
  GCGCCGTCACCCTGGCGCCCGCGGCCGACGACGCGGGAGAGCCGCCCCCAGTTGCGGGTAAATTGGGATA
  TTCACAATGTATGGAAACAGAGGTCATTGAATCTTTGGGAATTATTATTTATAAAGCACTGGACTATGGT
  TTGAAGGAGAATGAAGAAAGGGAATTAAGCCCTCCCCTAGAGCAGCTTATCGATCACATGGCCAACACGG
  TGGAAGCTGACGGTAGCAATGATGAGGGCTATGAGGCTGCAGAAGAAGGCCTGGGAGATGAAGATGAAAA
  GAGAAAAATCTCAGCTATTCGGTCATATAGAGATGTCATGAAGTTGTGTGCTGCTCATCTCCCTACTGAA
  TCAGATGCACCAAATCATTATCAGGCAGTATGTCGTGCACTGTTTGCAGAAACAATGGAGCTCCATACAT
  TTCTGACCAAAATTAAGAGTGCGAAAGAGAATCTTAAGAAGATTCAAGAAATGGAAAAGAGCGATGAATC
  TAGCACAGACTTGGAAGAGCTGAAAAACGCTGACTGGGCACGATTCTGGGTACAGGTGATGAGGGATTTG
  AGGAATGGGGTAAAACTTAAGAAGGTCCAAGAGCGGCAGTACAACCCTTTGCCCATTGAATATCAGCTCA
  CCCCTTATGAGATGTTAATGGATGACATTCGCTGCAAAAGATACACCTTGCGAAAAGTGATGGTGAATGG
  TGATATTCCCCCTCGGTTAAAAAAGAGTGCTCATGAAATCATCCTCGACTTCATCAGATCCAGACCTCCT
  TTAAATCCAGTCTCAGCCAGAAAACTGAAACCAACTCCACCACGGCCACGGAGCCTCCATGAAAGAATAT
  TAGAAGAAATTAAAGCAGAAAGAAAGCTGCGGCCTGTATCACCAGAGGAGATTAGACGTAGCAGATTAGA
  TGTGACTACCCCTGAATCTACAAAGAATCTTGTGGAGTCATCTATGGTGAATGGAGGTTTGACATCACAA
  ACAAAAGAAAACGGGTTAAGTACCTCACAGCAGGTGCCTGCACAGCGGAAGAAGCTCCTCAGAGCCCCAA
  CTCTGGCCGAACTGGACAGCTCTGAGTCTGAGGAAGAAACGCTGCACAAGTCGACCAGCAGCAGCAGCGT
  GTCTCCCTCTTTCCCTGAAGAGCCAGTCCTGGAGGCCGTGTCCACAAGGAAGAAGCCTCCAAAATTCCTG
  CCCATATCATCAACACCCCAGCCAGAGAGACGGCAGCCACCCCAGAGACGACATTCCATTGAAAAGGAAA
  CGCCTACTAACGTGAGGCAGTTCCTGCCGCCTTCCAGGCAGAGTTCCCGCTCTCTTGAGGAATTCTGCTA
  CCCAGTGGAATGCCTCGCTCTTACTGTGGAAGAAGTGATGCATATTCGCCAGGTCCTGGTGAAGGCAGAG
  CTGGAAAAATACCAACAGTATAAAGACATCTACACCGCCTTGAAAAAAGGAAAGCTCTGCTTTTGTTGCC
  GAACCAGGAGGTTTTCCTTCTTCACTTGGTCTTATACCTGTCAGTTCTGTAAGAGGCCGGTGTGCTCACA
  GTGTTGCAAAAAGATGCGGCTGCCCTCCAAACCATACTCCACTCTTCCTATCTTTTCATTGGGACCTTCT
  GCTCTGCAAAGAGGGGAAAGTAGTATGAGGTCAGAAAAACCCTCCACTGCCCATCATCGGCCACTTCGGA
  GCATTGCCAGGTTCTCCTCAAAATCTAAGTCTATGGACAAATCAGATGAAGAACTCCAGTTTCCCAAAGA
  GTTGATGGAGGACTGGAGCACCATGGAGGTGTGTGTGGACTGCAAGAAGTTCATTTCGGAAATCATCAGT
  TCAAGCCGGCGCAGTCTGGTGTTGGCCAACAAAAGGGCCCGATTGAAAAGGAAAACGCAGTCTTTCTACA
  TGTCCTCGCCAGGCCCCTCGGAGTACTGCCCTTCAGAGAGGACGATCAGTGAGATCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_020148
• ORF Size: 2229 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020148.2, NP_064533.3
• RefSeq Size: 5402
• RefSeq ORF: 2229
• Locus ID: 56907
• Protein Pathways: Dorso-ventral axis formation
• Gene Summary: Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.