PCDHA10 (NM_031860) Human Untagged Clone

CAT#: SC314426

PCDHA10 (untagged)-Human protocadherin alpha 10 (PCDHA10), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA10
• Synonyms: CNR8; CNRN8; CNRS8; CRNR8; PCDH-ALPHA10
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031860, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTTTCCAGATGTAGCTGCCTGGGGGTCCAGTGTCTGCTGCTCTCGCTTCTTCTCCTCGCAGCCTGGG
  AGGTGGGGAGCGGCCAGCTCCACTACTCAGTCTACGAGGAGGCCAGACACGGCACCTTCGTGGGCCGCAT
  CGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTGCAGCGCCTGTTCCGGGTGGCGTCCAAAAGACAC
  GGGGACCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAATTCTCGGATTGACCGCGAGGAGC
  TGTGCGGGCGGAGCGTGGAGTGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCA
  TGTGGACGTGGAAGTGAAGGACATTAACGACAACCCGCCCAGGTTCTCCGTAACAGAACAAAAGCTCTCA
  ATACCTGAATCCAGACTGCTTGACTCTCGATTTCCACTAGAAGGCGCATCTGATGCGGATGTTGGAGAGA
  ACGCATTGCTTACTTACAAACTCAGTCCAAATGAGTATTTTGTTCTTGATATTATAAACAAAAAAGACAA
  AGACAAATTCCCAGTGCTTGTTCTGCGGAAGCTGCTGGATCGTGAAGAAAATCCTCAGCTAAAGTTGTTG
  TTGACAGCAACTGATGGAGGCAAACCTGAATTTACCGGATCTGTTTCTCTGCTGATCCTGGTGTTAGATG
  CCAATGATAACGCCCCTATCTTTGACAGACCGGTTTATGAAGTTAAGATGTATGAAAATCAAGTGAACCA
  AACATTAGTAATACGGCTCAACGCTTCTGATTCGGATGAAGGAATAAACAAGGAAATGATGTATTCATTT
  AGCTCTTTGGTCCCACCCACGATAAGAAGGAAATTTTGGATAAACGAAAGGACGGGAGAAATAAAAGTAA
  ATGATGCTATTGACTTTGAGGACAGTAACACTTATGAAATTCATGTAGATGTTACAGATAAGGGAAACCC
  ACCTATGGTTGGTCACTGCACGGTCCTAGTGGAACTACTGGATGAAAATGATAATTCACCTGAGGTGATT
  GTCACTTCTCTGTCTCTCCCAGTGAAAGAAGATGCTCAAGTGGGCACCGTCATTGCCCTAATCAGCGTTT
  CTGACCATGATTCAGGAGCCAACGGACAGGTCACCTGCTCTCTGACGCCTCACGTTCCGTTCAAGCTGGT
  GTCCACCTACAAGAATTACTACTCATTGGTGCTGGACAGCGCTCTGGACCGCGAGAGGGTGTCGGCCTAT
  GAGCTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTCCGCTGTGGGCCACGGCCAGCGTGTCTGTGGAGG
  TGGCCGACGTGAACGACAACGCGCCTGCGTTCGCGCAGTCCGAGTACACGGTGTTCGTGAAGGAGAACAA
  CCCGCCAGGCTGCCACATCTTCACGGTGTCTGCGTGGGACGCGGACGCGCAGGAGAACGCCCTGGTGTCC
  TACTCTCTGGTGGAGCGGCGGTTGGGCGAGCGCTCGCTGTCGAGCTACGTGTCGGTGCACGCGGAGAGCG
  GCAAGGTGTACGCGCTGCAGCCGCTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGCCACGACAGCC
  CAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCACCTAGAGGAGGCT
  GGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACAGTATCCAGTGCAACACCAGAAC
  CAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACAGCTGGACCTTTAAATACGG
  ACCAGGCAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAATTCATTATCCCAGGATCTCCTGCA
  ATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAA
  AGGAGGAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGGAA
  CAGCACGACTGACAACAGTGACCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_031860
• ORF Size: 2058 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031860.2, NP_114066.1
• RefSeq Size: 4631
• RefSeq ORF: 2058
• Locus ID: 56139
• Protein Families: Secreted Protein
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) utilizes an alternative splice donor site that truncates exon 1. This shortest isoform (3) lacks the transmembrane region and has four complete and one partial cadherin domain.