MYOM1 (NM_019856) Human Untagged Clone

CAT#: SC316085

MYOM1 (untagged)-Human myomesin 1, 185kDa (MYOM1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MYOM1
• Synonyms: SKELEMIN
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_019856, the custom clone sequence may differ by one or more nucleotides
  ATGTCTTTGCCTTTTTATCAGAGGTGCCACCAGCACTATGATCTCAGCTACCGCAACAAG
  GACGTGCGCAGCACCGTGAGTCACTACCAGCGGGAGAAGAAACGCTCCGCCGTCTACACC
  CAGGGCTCCACGGCCTACAGCAGCCGCTCCTCCGCCGCGCACCGCCGGGAGTCCGAGGCC
  TTCCGTCGGGCGTCCGCCTCCTCCTCCCAGCAGCAGGCCTCGCAGCACGCCCTGAGCTCT
  GAAGTCAGTCGGAAGGCAGCCTCAGCCTACGATTATGGCTCCTCCCATGGACTTACAGAT
  TCCAGTCTGCTGTTAGATGATTATTCATCCAAGTTGAGCCCCAAACCAAAGAGAGCCAAG
  CACAGCCTACTGTCTGGAGAAGAGAAAGAAAATTTGCCCAGTGACTACATGGTACCCATT
  TTCTCAGGACGTCAAAAGCATGTCAGTGGAATTACTGATACGGAAGAAGAAAGAATTAAA
  GAAGCTGCTGCTTATATAGCCCAGAGGAATCTTCTTGCTAGTGAGGAAGGAATCACAACA
  TCTAAACAGTCCACGGCATCCAAGCAGACCACGGCATCTAAGCAGTCCACGGCATCCAAG
  CAGTCCACAGCATCCAAGCAGTCCACGGCATCCAGGCAGTCCACGGCATCCAGGCAGTCT
  GTGGTTTCCAAACAGGCCACATCCGCTCTTCAACAGGAAGAAACTTCTGAAAAGAAGTCA
  AGGAAAGTTGTGATTCGAGAAAAGGCAGAACGCCTGTCCCTGAGGAAAACATTAGAAGAA
  ACCGAGACATATCATGCCAAGCTGAATGAAGACCATCTTCTCCATGCTCCTGAGTTTATC
  ATTAAACCTCGCTCCCACACGGTTTGGGAGAAGGAGAATGTAAAATTGCATTGCTCCATA
  GCAGGCTGGCCAGAACCTCGTGTCACGTGGTATAAAAACCAGGTGCCAATAAATGTCCAT
  GCAAACCCTGGAAAGTATATTATTGAGAGTCGATATGGGATGCACACTCTGGAGATTAAT
  GGATGTGATTTTGAAGATACAGCTCAGTACCGGGCCTCGGCGATGAATGTTAAAGGAGAG
  CTTTCGGCATATGCTTCAGTTGTGGTAAAAAGGTATAAGGGAGAGTTTGATGAGACTCGC
  TTCCACGCTGGGGCTTCCACCATGCCCCTCAGCTTTGGTGTGACCCCATATGGTTATGCA
  TCCCGGTTTGAGATCCACTTTGATGACAAATTTGATGTGTCTTTTGGGAGAGAGGGAGAG
  ACAATGAGTCTAGGCTGTCGTGTTGTCATCACTCCTGAAATTAAACATTTCCAGCCAGAG
  ATCCAGTGGTACAGAAACGGAGTACCTCTTTCTCCATCAAAATGGGTGCAAACACTTTGG
  AGTGGAGAGCGGGCAACGCTGACATTTTCCCATCTCAACAAAGAAGATGAAGGCCTCTAT
  ACAATCCGTGTACGGATGGGAGAATATTATGAACAATATAGTGCTTATGTCTTTGTTCGA
  GATGCTGATGCAGAGATTGAAGGAGCCCCAGCTGCTCCCTTGGATGTGAAGTGCTTGGAG
  GCCAACAAAGATTATATCATCATCTCCTGGAAACAGCCAGCTGTCGATGGAGGGAGTCCT
  ATTCTCGGATATTTTATTGATAAGTGTGAGGTGGGCACAGATAGCTGGTCGCAGTGCAAT
  GACACACCTGTGAAGTTTGCTCGTTTTCCTGTCACTGGATTGATCGAAGGTCGTTCCTAT
  ATCTTCCGAGTTCGAGCTGTGAATAAAATGGGAATAGGTTTCCCATCTCGAGTTTCCGAG
  CCCGTGGCTGCTCTGGATCCGGCTGAGAAAGCTAGACTTAAAAGTCGCCCCTCAGCACCC
  TGGACTGGACAGATCATTGTTACTGAAGAGGAACCTTCAGAGGGTATTGTGCCTGGCCCC
  CCGACAGACCTCTCTGTCACTGAGGCCACCCGGAGCTATGTGGTGCTCAGCTGGAAGCCC
  CCTGGCCAGCGTGGTCATGAGGGCATTATGTACTTTGTGGAAAAGTGTGAGGCAGGAACA
  GAAAACTGGCAGCGAGTGAACACGGAGCTCCCTGTGAAGTCTCCCCGCTTTGCTCTGTTT
  GACTTGGCCGAGGGGAAATCCTACTGTTTCCGTGTCCGCTGTTCTAATTCTGCAGGAGTT
  GGTGAGCCCTCAGAGGCAACGGAGGTGACTGTGGTAGGGGACAAACTTGATATCCCCAAG
  GCTCCTGGCAAAATCATCCCAAGCAGAAACACAGACACCTCAGTGGTAGTTTCGTGGGAG
  GAGTCCAAAGATGCCAAAGAGCTGGTCGGGTACTACATAGAGGCGAGCGTTGCTGGCTCT
  GGCAAGTGGGAGCCCTGTAACAACAACCCCGTGAAGGGCTCACGATTCACTTGTCATGGA
  TTAGTGACTGGTCAGAGTTATATTTTCCGGGTCAGAGCAGTCAATGCAGCTGGACTTAGT
  GAATATTCCCAGGATTCAGAAGCTATTGAAGTCAAAGCTGCTATTGCACCACCATCTCCA
  CCCTGTGATATCACCTGTCTTGAAAGTTTTCGTGACTCAATGGTTCTTGGATGGAAGCAA
  CCAGATAAGATTGGAGGGGCAGAAATTACTGGCTATTATGTGAACTATCGCGAGGTCATT
  GATGGGGTACCAGGAAAATGGAGAGAAGCCAATGTCAAGGCTGTCAGTGAGGAGGCATAC
  AAGATTAGCAACTTGAAGGAAAACATGGTGTATCAGTTCCAAGTGGCAGCCATGAACATG
  GCTGGGCTGGGCGCGCCCTCCGCAGTAAGCGAATGCTTCAAATGTGAAGAGTGGACCATC
  GCCGTCCCAGGACCACCGCACAGTCTCAAGTGTAGTGAAGTCAGGAAAGACTCACTGGTT
  CTCCAGTGGAAGCCGCCAGTCCACTCCGGGCGGACTCCGGTCACTGGTTACTTCGTGGAC
  TTGAAGGAGGCCAAGGCCAAAGAAGACCAGTGGCGAGGGCTCAATGAGGCGGCTATTAAA
  AACGTATACCTGAAGGTTCGAGGCCTCAAGGAGGGCGTCAGCTACGTGTTCCGTGTTCGA
  GCCATAAACCAGGCGGGAGTTGGGAAGCCATCTGACCTTGCTGGCCCTGTTGTGGCAGAG
  ACCCGTCCAGGAACCAAAGAGGTTGTTGTAAATGTGGATGATGATGGAGTCATTTCATTG
  AACTTCGAGTGTGATAAGATGACTCCAAAGTCCGAGTTCTCCTGGTCCAAAGATTATGTA
  TCCACTGAGGACTCTCCACGATTGGAAGTCGAAAGCAAGGGCAACAAGACGAAAATGACC
  TTCAAAGACCTTGGGATGGATGACTTGGGTATTTACTCTTGCGATGTAACAGACACTGAT
  GGAATAGCATCAAGCTACTTAATAGATGAGGAAGAATTGAAACGTTTACTTGCTCTCAGC
  CATGAACACAAGTTCCCAACTGTCCCAGTTAAATCAGAGTTGGCAGTTGAAATTTTGGAG
  AAAGGCCAGGTCCGGTTTTGGATGCAGGCTGAGAAACTGTCTGGCAATGCCAAAGTCAAC
  TACATATTTAACGAGAAGGAAATTTTTGAAGGCCCGAAATATAAAATGCATATTGACCGA
  AACACTGGCATCATCGAAATGTTCATGGAAAAGCTACAGGATGAGGATGAGGGAACGTAC
  ACTTTCCAGCTTCAAGATGGAAAAGCAACTAACCATTCTACTGTTGTTCTCGTTGGAGAT
  GTTTTCAAAAAGCTCCAGAAAGAAGCTGAATTCCAGCGGCAAGAATGGATCAGGAAACAA
  GGTCCTCACTTTGTTGAGTATTTGAGCTGGGAAGTGACTGGTGAATGTAATGTACTATTG
  AAATGCAAGGTGGCAAATATTAAGAAGGAGACTCATATTGTGTGGTACAAAGATGAGAGG
  GAGATATCAGTGGATGAAAAGCATGACTTTAAGGATGGTATATGTACCCTGCTTATAACA
  GAGTTTTCCAAGAAAGATGCTGGGATTTATGAAGTTATCCTGAAAGATGACCGAGGAAAA
  GATAAGAGCAGACTGAAGCTTGTGGATGAAGCCTTTAAGGAACTGATGATGGAAGTATGC
  AAAAAAATAGCTTTGTCTGCTACAGACCTGAAAATCCAGAGCACAGCCGAGGGCATCCAA
  CTGTACTCTTTTGTAACTTACTATGTGGAGGATTTGAAAGTTAACTGGTCCCACAATGGG
  TCCGCCATTAGGTACTCAGACAGAGTTAAGACCGGGGTCACTGGAGAGCAGATCTGGCTA
  CAAATCAACGAGCCCACCCCGAATGACAAAGGGAAGTATGTCATGGAGCTCTTTGATGGC
  AAAACTGGACATCAGAAGACAGTGGATCTCTCTGGACAAGCATACGATGAGGCCTATGCT
  GAATTCCAGAGGTTGAAACAAGCTGCCATTGCCGAGAAAAATCGTGCCCGGGTGTTGGGA
  GGTCTCCCAGACGTGGTCACCATCCAGGAGGGGAAGGCCCTTAATCTCACTTGCAACGTG
  TGGGGAGACCCGCCTCCGGAGGTGTCGTGGTTGAAGAACGAGAAGGCCCTGGCCTCAGAC
  GACCACTGCAACCTCAAGTTCGAGGCTGGGAGGACCGCGTACTTCACCATCAACGGCGTG
  AGCACCGCTGACTCGGGCAAATACGGGCTGGTTGTGAAGAACAAGTATGGCTCGGAGACC
  AGCGACTTCACCGTCAGCGTGTTCATCCCAGAGGAGGAGGCGAGGATGGCCGCCTTGGAG
  TCCCTGAAAGGTGGCAAGAAGGCCAAG
  
• Restriction Sites: Please inquire
• ACCN: NM_019856
• ORF Size: 4770 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_019856.1, NP_062830.1
• RefSeq Size: 5560
• RefSeq ORF: 4770
• Locus ID: 8736
• Gene Summary: The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (b), that is missing an internal segment compared to isoform a.