MCC (NM_001085377) Human Untagged Clone

CAT#: SC316287

MCC (untagged)-Human mutated in colorectal cancers (MCC), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCC
• Synonyms: MCC1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001085377, the custom clone sequence may differ by one or more nucleotides
  ATGATGGCGGCCGCGGCGGCAGCGGCTGCGGGGAGCTCCAGCAGCGGCGGCGGCGGCGGC
  GGCAGCGGCAGCAGCAGCAGCAGCAGCGACACGTCCAGCACCGGCGAGGAGGAGAGGATG
  CGGCGCCTCTTCCAGACGTGCGACGGCGACGGGGACGGATACATCAGCAGAAATGACTTG
  CTAATGGTCTGTCGCCAGCTGAATATGGAAGAGTCTGTGGCTGAGATCATGAACCAGTTG
  GGAGCAGATGAAAATGGGAAGATTTCCTTTCAGGATTTCACAAGATGCCGCATGCAGCTT
  GTTCGAGAAATTAGGAAGGAGGAAGTAGATCTTTCTGCAAAGTCAGACAACTCCTGTACA
  AAGAAGCTGAGGGATAGAATTGCTTCCTGGCCCACGAGCAGTGACAACAGTTTGGGTGCC
  TTATCAGCAGCCAGGGAGAGCTGGGAATACGACTCTGGTGCCAGGGACCTCCAGAGCCCG
  GATGTGCAGAGCCAGTCAGCCCTCCAGAAGCTGCTCGAGTATGGCGGAAGCTCTTTGCAT
  CAGCAGGCTGCTCTCCACAAACTGCTCACACAGTCCCCGCACATTGGCAACTCTGTAGGA
  GGAAGCTATCTAGAGCTGGCCAACACACTCCATTCAGCAGCCCTGGCATCACTAAAGGGA
  GATATAGTGGAACTTAATAAACGTCTCCAGCAAACAGAGAGGGAACGGGACCTTCTGGAA
  AAGAAATTGGCCAAGGCACAGTGCGAGCAGTCCCACCTCATGAGAGAGCATGAGGATGTC
  CAGGAGCGAACGACACTTCGCTATGAGGAACGCATCACAGAGCTCCACAGCGTCATTGCG
  GAGCTCAACAAGAAGATAGACCGTCTGCAAGGCACCACCATCAGGGAGGAAGATGAGTAC
  TCAGAACTGCGATCAGAACTCAGCCAGAGCCAACACGAGGTCAACGAGGACTCTCGAAGC
  ATGGACCAAGACCAGACCTCTGTCTCTATCCCCGAAAACCAGTCTACCATGGTTACTGCT
  GACATGGACAACTGCAGTGACCTGAACTCAGAACTGCAGAGGGTGCTGACAGGGCTGGAG
  AATGTTGTCTGCGGCAGGAAGAAGAGCAGCTGCAGCCTCTCCGTGGCCGAGGTGGACAGG
  CACATTGAGCAGCTCACCACAGCCAGCGAGCACTGTGACCTGGCTATTAAGACAGTCGAG
  GAGATTGAGGGGGTGCTTGGCCGGGACCTGTATCCCAACCTGGCTGAAGAGAGGTCTCGG
  TGGGAGAAGGAGCTGGCTGGGCTGAGGGAAGAGAATGAGAGCCTGACTGCCATGCTGTGC
  AGCAAAGAGGAAGAACTGAACCGGACTAAGGCCACCATGAATGCCATCCGGGAAGAGCGG
  GACCGGCTCCGGAGGAGGGTCAGAGAGCTTCAAACTCGACTACAGAGCGTGCAGGCCACA
  GGTCCCTCCAGCCCTGGCCGCCTCACTTCCACCAACCGCCCGATTAACCCCAGCACTGGG
  GAGCTGAGCACAAGCAGCAGCAGCAATGACATTCCCATCGCCAAGATTGCTGAGAGGGTG
  AAGCTATCAAAGACAAGGTCCGAATCGTCATCATCTGATCGGCCAGTCCTGGGCTCAGAA
  ATCAGTAGCATAGGGGTATCCAGCAGTGTGGCTGAACACCTGGCCCACTCACTTCAGGAC
  TGCTCCAATATCCAAGAGATTTTCCAAACACTCTACTCACACGGATCTGCCATCTCAGAA
  AGCAAGATTAGAGAGTTTGAGGTGGAAACAGAACGGCTGAATAGCCGGATTGAGCACCTC
  AAATCCCAAAATGACCTCCTGACCATAACCTTGGAGGAATGTAAAAGCAATGCCGAGAGG
  ATGAGCATGCTGGTGGGAAAATACGAATCCAATGCCACAGCGCTGAGGCTGGCCTTGCAG
  TACAGCGAGCAGTGCATCGAAGCCTACGAACTCCTCCTGGCGCTGGCAGAGAGTGAGCAG
  AGCCTCATCCTGGGGCAGTTCCGAGCGGCGGGCGTGGGGTCCTCCCCTGGAGACCAGTCG
  GGGGATGAAAACATCACTCAGATGCTCAAGCGAGCTCATGACTGCCGGAAGACAGCTGAG
  AACGCTGCCAAGGCCCTGCTCATGAAGCTGGACGGCAGCTGTGGGGGAGCCTTTGCCGTG
  GCCGGCTGCAGCGTGCAGCCCTGGGAGAGCCTTTCCTCCAACAGCCACACCAGCACAACC
  AGCTCCACAGCCAGTAGTTGCGACACCGAGTTCACTAAAGAAGACGAGCAGAGGCTGAAG
  GATTATATCCAGCAGCTCAAGAATGACAGGGCTGCGGTCAAGCTGACCATGCTGGAGCTG
  GAAAGCATCCACATCGATCCTCTCAGCTATGACGTCAAGCCTCGGGGAGACAGCCAGAGG
  CTGGATCTGGAAAACGCAGTGCTTATGCAGGAGCTCATGGCCATGAAGGAGGAGATGGCC
  GAGTTGAAGGCCCAGCTCTACCTACTGGAGAAAGAGAAGAAGGCCCTGGAGCTGAAGCTG
  AGCACGCGGGAGGCCCAGGAGCAGGCCTACCTGGTGCACATTGAGCACCTGAAGTCCGAG
  GTGGAGGAGCAGAAGGAGCAGCGGATGCGATCCCTCAGCTCCACCAGCAGCGGCAGCAAA
  GACAAACCTGGCAAGGAGTGTGCTGATGCTGCCTCCCCAGCTCTGTCCCTAGCCGAACTC
  AGGACAACGTGCAGCGAGAATGAGCTGGCTGCGGAGTTCACCAACGCCATTCGTCGAGAA
  AAGAAGTTGAAGGCCAGAGTTCAAGAGCTGGTGAGTGCCTTGGAGAGACTCACCAAGAGC
  AGTGAAATCCGACATCAGCAATCTGCAGAGTTCGTGAATGATCTAAAGCGGGCCAACAGC
  AACCTGGTGGCTGCCTATGAGAAAGCAAAGAAAAAGCATCAAAACAAACTGAAGAAGTTA
  GAGTCGCAGATGATGGCCATGGTGGAGAGACATGAGACCCAAGTGAGGATGCTCAAGCAA
  AGAATAGCTCTGCTAGAGGAGGAGAACTCCAGGCCACACACCAATGAAACTTCGCTT
  
• Restriction Sites: Please inquire
• ACCN: NM_001085377
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001085377.1, NP_001078846.1
• RefSeq Size: 8679 bp
• RefSeq ORF: 3060 bp
• Locus ID: 4163
• Cytogenetics: 5q22.2
• Protein Families: Druggable Genome
• Gene Summary: 'This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.