SRC3 (NCOA3) (NM_006534) Human Untagged Clone

CAT#: SC316311

NCOA3 (untagged)-Human nuclear receptor coactivator 3 (NCOA3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NCOA3
• Synonyms: ACTR; AIB-1; AIB1; bHLHe42; CAGH16; CTG26; KAT13B; pCIP; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006534 edited
  GCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGGGAGGATCAAAAT
  ACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAACATCCTTTGACT
  GGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGATTAGGAGAAAACTTGGATCCAC
  TGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGACAAGGTCTTACCT
  GCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGAATTGGCTGAGC
  TGATATCTGCCAATCTTAGTGATATTGACAATTTCAATGTCAAACCAGATAAATGTGCGA
  TTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCA
  ATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAG
  ACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGTTTCCTATTTGTGGTGAATCGAG
  ACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAATATAAGCAAGAGG
  ACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAAAGGATTTTCTTA
  AGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGGACAAATGAGACCCAAAGACAAA
  AAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATATTCTGGAAGACA
  TAAACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTC
  AGCCACGAGCTATGATGGAGGAAGGGGAAGATTTGCAATCTTGTATGATCTGTGTGGCAC
  GCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACCCTGAGAGCTTTATTACCAGAC
  ATGATCTTTCAGGAAAGGTTGTCAATATAGATACAAATTCACTGAGATCCTCCATGAGGC
  CTGGCTTTGAAGATATAATCCGAAGGTGTATTCAGAGATTTTTTAGTCTAAATGATGGGC
  AGTCATGGTCCCAGAAACGTCACTATCAAGAAGCTTATCTTAATGGCCATGCAGAAACCC
  CAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAAC
  TCTTCCGAAATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGA
  GAGAACAGAATGGATATAGACCAAACCCAAATCCTGTTGGACAAGGGATTAGACCACCTA
  TGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGA
  TGCCGAGCAGCAGGGCCTATGGCTTGGCAGACCCTAGCACCACAGGGCAGATGAGTGGAG
  CTAGGTATGGGGGTTCCAGTAACATAGCTTCATTGACCCCTGGGCCAGGCATGCAATCAC
  CATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCCACATGGGAGTC
  CTGGTCTTGCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCAA
  AGATAGCCTCACATCAGTTTTCTCCTGTTGCAGGTGTGCACTCTCCCATGGCATCTTCTG
  GCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTG
  AAGGTGTGGGGACTTCCCTTTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACT
  CTCCCAATATGAATATTACCCAACCAAGTAAAGTAAGCAATCAGGATTCCAAGAGTCCTC
  TGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAATGTGTCAGTCAAATAGCAGAG
  ATCACCTCAGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGAGAATCAAAGGG
  GTCCTTTGGAAAGCAAAGGTCATAAAAAATTACTGCAGTTACTTACCTGTTCTTCTGATG
  ACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTG
  TTAGTGTCACCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACAT
  CCAATATGCATGGGTCACTGTTACAAGAGAAGCACCGGATTTTGCACAAGTTGCTGCAGA
  ATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAGAAGCCACTGGGAAAGACACCA
  GCAGTATAACTTCTTGTGGGGACGGAAATGTTGTCAAGCAGGAGCAGCTAAGTCCTAAGA
  AGAAGGAGAATAATGCACTTCTTAGATACCTGCTGGACAGGGATGATCCTAGTGATGCAC
  TCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACCA
  GCTCCACCATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTG
  AAGAGGGATCTGGAGACTTGGATAATCTAGATGCTATTCTTGGTGATCTGACTAGTTCTG
  ACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGT
  TTCAAGGAACTAATTCTCTGGGTTTGAAAAGTTCACAGTCTGTGCAGTCTATTCGTCCTC
  CATATAACCGAGCAGTGTCTCTGGATAGCCCTGTTTCTGTTGGCTCAAGTCCTCCAGTAA
  AAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGGGAATCCAAGAA
  TGATGGATAGTCAGGAAAATTATGGCTCAAGTATGGGTGGGCCAAACCGAAATGTGACTG
  TGACTCAGACTCCTTCCTCAGGAGACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGG
  AACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGAGATTATAATACTTCTTTACCCA
  GACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTG
  CGAGACCAGTATTGCAACAGCAGCAGCAGATGCTTCAAATGAGGCCTGGTGAAATCCCCA
  TGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCATCTAACCAACTGGGTTCCTGGC
  CCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAATAGGCCTCTTCTTA
  GGAATTCCCTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAAA
  GAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAACACAGATGCCACAGGCCTGGAAG
  AAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCA
  AACAGGATGCTTTCCAAGGCCAAGAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTAT
  ATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAAGGAGGCTTTCATCTTCAGGGAC
  AATCACCATCTTTTAACTCTATGATGAATCAGATGAACCAGCAAGGCAATTTTCCTCTCC
  AAGGAATGCACCCACGAGCCAACATCATGAGACCCCGGACAAACACCCCCAAGCAACTTA
  GAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGACAGGCAC
  TTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGC
  AGCCCCAGCAGGGTTTTCTTAATGCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAA
  GTCATCACTTCCGACAACAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAGCAGCAAC
  AGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGC
  AGCAAACCCAGGCCTTCAGCCCACCTCCTAATGTGACTGCTTCCCCCAGCATGGATGGGC
  TTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCAACAGTTTCCATATCAACCAAATT
  ATGGAATGGGACAACAACCAGATCCAGCCTTTGGTCGAGTGTCTAGTCCTCCCAATGCAA
  TGATGTCGTCAAGAATGGGTCCCTCCCAGAATCCCATGATGCAACACCCGCAGGCTGCAT
  CCATCTATCAGTCCTCAGAAATGAAGGGCTGGCCATCAGGAAATTTGGCCAGGAACAGCT
  CCTTTTCCCAGCAGCAGTTTGCCCACCAGGGGAATCCTGCAGTGTATAGTATGGTGCACA
  TGAATGGCAGCAGTGGTCACATGGGACAGATGAACATGAACCCCATGCCCATGTCTGGCA
  TGCCTATGGGTCCTGATCAGAAATACTGCTGACATCTCTGCACCAGGACCTCTTAAGGAA
  ACCACTGTACAAATGACACTGCACTAGGATTATTGGGAAGGAATCATTGTTCCAGGCATC
  CATCTTGGAAGAAAGGACCAGCTTTGAGCTCCATCAAGGGTATTTTAAGTGATGTCATTT
  GAGCAGGACTGGATTTTAAGCCGAAGGGCAATATCTACGTGTTTTTCCCCCCTCCTTCTG
  CTGTGTATCATGGTGTTCAAAACAGAAATGTTTTTTGGCATTCCACCTCCTAGGGATATA
  ATTCTGGAGACATGGAGTGTTACTGATCATAAAACTTTTGTGTCACTTTTTTCTGCCTTG
  CTAGCCAAAATCTCTTAAATACACGTAGGTGGGCCAGAGAACATTGGAAGAATCAAGAGA
  GATTAGAATATCTGGTTTCTCTAGTTGCAGTATTGGACAAAGAGCATAGTCCCAGCCTTC
  AGGTGTAGTAGTTCTGTGTTGACCCTTTGTCCAGTGGAATTGGTGATTCTGAATTGTCCT
  TTACTAATGGTGTTGAGTTGCTCTGTCCCTATTATTTGCCCTAGGCTTTCTCCTAATGAA
  GGTTTTCATTTGCCATTCATGTCCTGTAATACTTCACCTCCAGGAACTGTCATGGATGTC
  CAAATGGCTTTGCAGAAAGGAAATGAGATGACAGTATTTAATCGCAGCAGTAGCAAACTT
  TTCACATGCTAATGTGCAGCTGAGTGCACTTTATTTAAAAAGAATGGATAAATGCAATAT
  TCTTGAGGTCTTGAGGGAATAGTGAAACACATTCCTGGTTTTTGCCTACACTTACGTGTT
  AGACAAGAACTATGATTTTTTTTTTAAAGTACTGGTGTCACCCTTTGCCTATATGGTAGA
  GCAATAATGCTTTTTAAAAATAAACTTCTGAAAACCCAAGGCCAGGTACTGCATTCTGAA
  TCAGAATCTCGCAGTGTTTCTGTGAATAGATTTTTTTGTAAATATGACCTTTAAGATATT
  GTATTATGTAAAATATGTATATACCTTTTTTTGTAGGTCACAACAACTCATTTTTACAGA
  GTTTGTGAAGCTAAATATTTAACATTGTTGATTTCAGTAAGCTGTGTGGTGAGGCTACCA
  GTGGAAGAGACATCCCTTGACTTTTGTGGCCTGGGGGAGGGGTAGTGCTCCACAGCTTTT
  CCTTCCCCACCCCCCAGCCTTAGATGCCTCGCTCTTTTCAATCTCTTAATCTAAATGCTT
  TTTAAAGAGATTATTTGTTTAGATGTAGGCATTTTAATTTTTTAAAAATTCCTCTACCAG
  AACTAAGCACTTTGTTAATTTGGGGGGAAAGAATAGATATGGGGAAATAAACTTAAAAAA
  AAATCAGGAATTTAAAAAAACGAGCAATTTGAAGAGAATCTTTTGGATTTTAAGCAGTCC
  GAAATAATAGCAATTCATGGGCTGTGTGTGTGTGTGTATGTGTGTGTGTGTGTGTGTATG
  TTTAATTATGTTACCTTTTCATCCCCTTTAGGAGCGTTTTCAGATTTTGGTTGCTAAGAC
  CTGAATCCCATATTGAGATCTCGAGTAGAATCCTTGGTGTGGTTTCTGGTGTCTGCTCAG
  CTGTCCCCTCATTCTACTAATGTGATGCTTTCATTATGTCCCTGTGGATTAGAATAGTGT
  CAGTTATTTCTTAAGTAACTCAGTACCCAGAACAGCCAGTTTTACTGTGATTCAGAGCCA
  CAGTCTAACTGAGCACCTTTTAAACCCCTCCCTCTTCTGCCCCCTACCACTTTTCTGCTG
  TTGCCTCTCTTTGACACCTGTTTTAGTCAGTTGGGAGGAAGGGAAAAATCAAGTTTAATT
  CCCTTTATCTGGGTTAATTCATTTGGTTCAAATAGTTGACGGAATTGGGTTTCTGAATGT
  CTGTGAATTTCAGAGGTCTCTGCTAGCCTTGGTATCATTTTCTAGCAATAACTGAGAGCC
  AGTTAATTTTAAGAATTTCACACATTTAGCCAATCTTTCTAGATGTCTCTGAAGGTAAGA
  TCATTTAATATCTTTGATATGCTTACGAGTAAGTGAATCCTGATTATTTCCAGACCCACC
  ACCAGAGTGGATCTTATTTTCAAAGCAGTATAGACAATTATGAGTTTGCCCTCTTTCCCC
  TACCAAGTTCAAAATATATCTAAGAAAGATTGTAAATCCGAAAACTTCCATTGTAGTGGC
  CTGTGCTTTTCAGATAGTATACTCTCCTGTTTGGAGACAGAGGAAGAACCAGGTCAGTCT
  GTCTCTTTTTCAGCTCAATTGTATCTGACCCTTCTTTAAGTTATGTGTGTGGGGAGAAAT
  AGAATGGTGCTCTTATCTTTCTTGACTTTAAAAAAATTATTAAAAACAAAAAAAAAATAA
  ATTTTTTTGCAATCCTTTCCTCAGACCTGGCTCCAGGCTAACTGGAAGGCAGCGCTCCCT
  TTTTTATATAGTAGAAAAATGAAGTTTATTATAAGTTTTTATATTTTCTACTTGTTCATT
  TGGTGCAAACTCAAGATTTCTTTTAATAGGTGCAGTCTTTGAGATAATTTGTTTTTACCT
  GTATTGCCCTTTATCTTTTTTAGGTAATTCTTTGTACTCCTGCTGTCTACCTCTCCTCAC
  ACCCCAGCACCCCCCATTTTTTCAAACCTTGGTATCTGTTGGGTGAACAGTATAATCTTT
  TCATCTGCTTTTAGAATGTGGGATATTTCCAGTACCTACTTTTTTTTTTTTTTTTGCTGA
  ATCCAAAGATATATAAATAAAATATATATTTTATAAAGATCAGAATGATATAAAGGAGAT
  ACATGTTTCTTCCTTTAAAAAATAAACGGAAGTTACATTGTTAATGTTCATATTATGATG
  CCACTTTTCTAAACTGCATCTGGATTGAAAGGTGTAAATATCAATAACAGTGCTACTTAG
  TTATCAGTATTTAATATCTGAGGTGAGTTGGGGGTATCTATATTAGGGGTAGGGTATTAC
  AGAAGATAATTGGCTTGATGTCCTAGAAGTTCTTTGATCCAGAGGTGGGTGCA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006534 unedited
  GGGGCACCGTATGTAATACGACTCCTATAGGGCGGCCGCGCAGTGTGATGGATATCTGCA
  GAATTCGCCCTTGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAATGGCGGCGG
  GAGGATCAAAATACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCTTGAA
  CATCCTTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGATTAGGAGAAA
  ACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCAGGAC
  AAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAG
  AATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAATGTCAAACCAG
  ATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAA
  AAACTATTTCCAATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAG
  TTATTGATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGTTTCCTATTTG
  TGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTGCAAT
  ATAAGCAAGAGGACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAGAAGACAGAA
  AGGATTTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGGACAAATGAGA
  CCCAAAGACAAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCCACATGA
  TATTCTGGAAGACAAAAACGCAGTCCTGAAATGCGCCAGAGATATGAAACATGCATGCTT
  TGCCTGTTCTTCAGCCACGAGCTTATGATGGAGAGGGGAAGAATTTGGCAATCCCTTTGT
  TATGATTCTCTTTTTT
  
• Restriction Sites: Please inquire
• ACCN: NM_006534
• ORF Size: 4263 bp
• Insert Size: 7400
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006534.2, NP_006525.2
• RefSeq Size: 7923
• RefSeq ORF: 4263
• Locus ID: 8202
• Domains: PAS, HLH
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1, resulting in a shorter isoform (b) compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.