IQSEC2 (NM_001111125) Human Untagged Clone

CAT#: SC317211

IQSEC2 (untagged)-Human IQ motif and Sec7 domain 2 (IQSEC2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IQSEC2
• Synonyms: BRAG1; IQ-ArfGEF; MRX1; MRX18; MRX78
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001111125, the custom clone sequence may differ by one or more nucleotides
  ATGGAGGCGGGGTCGGGGCCCCCGGGCGGCCCGGGATCCGAGAGCCCAAATCGGGCCGTG
  GAGTACCTGCTGGAGCTGAACAACATCATCGAGAGCCAGCAGCAGCTGCTGGAAACCCAG
  CGGCGGCGCATCGAGGAGCTGGAGGGCCAGCTGGACCAGCTCACCCAGGAGAACCGCGAC
  CTGCGAGAGGAGAGCCAGCTGCACCGCGGGGAGCTGCACCGGGACCCCCACGGCGCGCGG
  GATAGCCCGGGCCGCGAGAGCCAGTACCAGAACCTGCGCGAGACCCAGTTCCACCACCGC
  GAGCTGCGGGAGAGCCAGTTCCACCAGGCGGCCCGGGACGTGGGCTACCCGAACCGGGAA
  GGCGCCTACCAGAATCGGGAGGCTGTGTATCGGGACAAGGAGCGGGACGCCTCCTACCCG
  CTCCAGGACACTACCGGTTACACAGCCCGCGAGCGTGACGTGGCCCAGTGCCACCTGCAC
  CACGAGAACCCAGCCCTGGGTCGCGAGCGTGGCGGGCGGGAGGCCGGGCCGGCGCACCCG
  GGCCGCGAGAAGGAAGCGGGCTATTCGGCGGCGGTGGGCGTGGGGCCGCGGCCACCGCGG
  GAGCGGGGCCAGCTGAGCCGTGGCGCATCCAGGAGCTCCAGTCCCGGCGCCGGCGGAGGC
  CACAGCACCAGTACCAGCACCAGCCCGGCCACGACCCTCCAGAGAAAATCTGATGGTGAG
  AATTCCAGAACAGTCAGTGTGGAGGGTGATGCCCCAGGCAGTGACCTGAGCACAGCGGTT
  GATAGTCCTGGGAGCCAACCCCCCTACCGGCTGAGCCAGCTGCCCCCCTCCAGCAGCCAC
  ATGGGGGGCCCCCCTGCTGGAGTGGGCCTTCCCTGGGCTCAGCGGGCACGCCTCCAGCCA
  GCCAGTGTCGCCCTGAGGAAGCAGGAGGAGGAGGAGATAAAGCGCTCCAAGGCCCTATCG
  GACAGCTATGAACTCTCCACAGACCTGCAGGACAAGAAGGTGGAAATGCTGGAGAGGAAG
  TATGGGGGCTCCTTCCTGAGCCGCAGGGCTGCCAGGACCATCCAGACAGCCTTCCGCCAG
  TACCGCATGAACAAGAACTTTGAGCGGCTACGCAGCTCAGCCTCAGAGAGCCGCATGTCC
  CGCCGCATCATCCTTTCCAACATGCGGATGCAGTTCTCCTTTGAGGAGTATGAGAAGGCA
  CAGAACCCCGCGTACTTCGAGGGCAAGCCTGCCTCGCTGGACGAGGGTGCCATGGCTGGT
  GCCCGGAGCCACCGGCTTGAACGGGGGCTCCCATATGGAGGCTCCTGTGGTGGGGGCATC
  GATGGTGGTGGAAGCTCCGTCACCACATCTGGAGAGTTTTCTAATGACATCACAGAACTT
  GAGGACTCCTTCTCCAAACAGGTAAAGTCTCTGGCTGAATCCATCGACGAAGCCCTGAAC
  TGCCACCCGTCAGGGCCCATGTCTGAGGAGCCAGGGTCAGCCCAGCTGGAGAAGCGGGAG
  TCAAAGGAACAGCAAGAGGACAGCTCAGCCACATCCTTCAGTGATCTTCCCCTCTACCTG
  GATGACACAGTTCCCCAACAATCCCCTGAGCGACTGCCCAGCACAGAACCCCCACCCCAG
  GGCCGGCCCGAGTTCTGGGCGCCAGCCCCTCTCCCGCCAGTTCCTCCACCAGTGCCATCA
  GGAACCCGGGAAGACGGTAGCCGTGAGGAAGGCACTCGCAGGGGTCCCGGGTGCTTGGAG
  TGCCGGGATTTCCGGCTGCGGGCTGCCCACCTTCCCCTGCTTACCATTGAGCCTCCTAGT
  GACAGCTCCGTGGACCTGAGTGACCGCTCAGATCGCGGCTCTGTCCACCGCCAGCTGGTG
  TATGAGGCTGATGGCTGCAGCCCCCATGGGACCCTGAAGCACAAGGGGCCACCAGGCAGG
  GCCCCGATCCCACACCGCCACTACCCAGCCCCTGAAGGCCCAGCCCCAGCCCCACCAGGG
  CCCCTGCCACCAGCCCCCAACAGTGGCACTGGGCCCAGTGGTGTGGCTGGGGGTCGGAGG
  TTGGGGAAGTGCGAGGCAGCAGGCGAGAACTCTGATGGTGGAGATAACGAGAGCCTTGAG
  AGCTCCAGCAATTCCAATGAGACCATCAACTGCAGCTCCGGCTCCTCTTCTCGGGACAGT
  CTAAGGGAGCCTCCGGCTACCGGCCTGTGCAAGCAGACTTACCAGCGGGAGACAAGGCAT
  AGCTGGGACTCGCCAGCTTTCAACAATGATGTGGTCCAGAGGCGGCACTACCGAATCGGC
  CTCAACCTCTTCAACAAGAAGCCAGAGAAGGGTATCCAGTATCTGATCGAGCGGGGCTTC
  CTGTCAGACACACCGGTGGGAGTGGCTCACTTCATCCTGGAGCGGAAAGGCCTCAGCCGG
  CAGATGATAGGGGAATTCCTAGGGAACCGGCAGAAGCAGTTCAACAGAGACGTGTTGGAC
  TGTGTGGTGGATGAGATGGACTTCTCCTCCATGGATCTGGATGATGCGCTCCGGAAGTTC
  CAGTCCCATATCCGGGTTCAGGGTGAGGCCCAGAAAGTGGAGCGACTCATCGAAGCCTTC
  AGCCAGCGGTACTGTGTCTGTAACCCAGCCCTCGTGCGCCAGTTCCGGAACCCAGACACC
  ATCTTCATCCTTGCTTTTGCCATCATCCTCCTCAATACCGACATGTACAGTCCCAGCGTC
  AAAGCTGAACGAAAGATGAAACTAGATGACTTCATCAAGAACCTGAGAGGGGTTGACAAT
  GGTGAAGACATCCCCCGAGACCTCCTGGTGGGCATCTACCAGCGCATCCAGGGGCGTGAA
  CTGCGGACCAACGATGACCATGTGTCCCAGGTGCAGGCTGTGGAGCGCATGATTGTTGGA
  AAGAAACCAGTCCTGTCTCTCCCTCACCGTCGACTGGTTTGCTGCTGCCAGCTCTACGAG
  GTGCCAGATCCAAACCGCCCCCAGAGGCTAGGGTTGCATCAGCGGGAGGTCTTCCTCTTC
  AATGATCTCCTTGTGGTCACCAAAATTTTCCAGAAGAAGAAGATCTTGGTGACGTACAGT
  TTCCGTCAGTCTTTCCCCCTCGTGGAAATGCACATGCAGCTCTTCCAGAATTCATATTAC
  CAGTTTGGGATCAAGTTGCTGTCTGCAGTACCTGGTGGGGAGCGAAAAGTCCTCATCATC
  TTCAATGCCCCCAGCCTCCAGGACCGGCTGCGCTTTACATCCGACCTGCGCGAGTCCATT
  GCGGAGGTGCAGGAGATGGAGAAATACCGTGTGGAGTCGGAGCTGGAGAAGCAGAAAGGT
  ATGATGCGGCCTAACGCCTCACAGCCTGGAGGGGCCAAGGACTCAGTGAATGGGACGATG
  GCCCGCAGTAGCCTGGAGGACACTTACGGGGCAGGCGATGGGCTCAAACGGGGCGCACTC
  AGCAGTTCCCTGCGAGACCTCTCTGATGCAGGGAAGCGGGGGCGGCGTAACAGCGTGGGA
  TCGCTGGACAGCACCATCGAAGGGTCTGTTATTAGCAGTCCACGCCCTCACCAGAGGATG
  CCACCTCCGCCCCCACCCCCGCCGCCAGAGGAGTACAAGAGCCAGAGGCCCGTCTCCAAC
  TCCTCATCCTTCCTGGGCTCCCTATTTGGAAGCAAGCGGGGCAAGGGGCCCTTCCAGATG
  CCACCACCGCCAACAGGCCAGGCCTCTGCCTCCTCTTCATCTGCTTCTTCCACGCACCAC
  CACCACCACCACCACCATCATGGCCATAGCCACGGTGGCCTGGGGGTGCTGCCTGATGGG
  CAGTCCAAGCTCCAGGCCCTGCATGCCCAGTATTGCCAAGGACCGGGCCCTGCCCCGCCA
  CCCTACCTCCCACCCCAGCAGCCCTCTCTTCCCCCACCTCCCCAGCAGCCCCCACCCTTG
  CCCCAGCTGGGCTCCATTCCACCGCCTCCCGCCTCAGCCCCACCTGTGGGGCCACATCGC
  CACTTCCACGCCCATGGCCCAGTCCCAGGGCCCCAACACTATACCTTGGGCCGGCCAGGC
  AGGGCACCCAGACGGGGGGCTGGAGGACACCCTCAGTTTGCTCCACATGGCCGCCACCCC
  CTGCACCAGCCCACATCCCCACTGCCCCTGTACAGTCCTGCCCCCCAGCACCCTCCAGCC
  CACAAACAGGGCCCTAAGCACTTCATCTTCAGCCACCACCCACAGATGATGCCAGCAGCA
  GGCGCGGCTGGGGGCCCTGGATCCCGGCCACCAGGGGGCTCCTACTCCCACCCCCACCAC
  CCCCAGTCACCATTGTCACCACACTCACCCATCCCACCCCACCCCTCCTATCCACCCCTC
  CCCCCACCCTCCCCTCACACCCCGCACTCACCCCTTCCACCCACCTCCCCCCATGGCCCG
  CTGCACGCCTCTGGGCCCCCTGGCACAGCCAACCCCCCCAGTGCAAACCCCAAGGCCAAG
  CCAAGCCGGATCAGCACCGTGGTC
  
• Restriction Sites: Please inquire
• ACCN: NM_001111125
• ORF Size: 4467 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001111125.1, NP_001104595.1
• RefSeq Size: 6004
• RefSeq ORF: 4467
• Locus ID: 23096
• Protein Pathways: Endocytosis
• Gene Summary: This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.