STEAP4 (NM_024636) Human Untagged Clone

CAT#: SC317754

STEAP4 (untagged)-Human STEAP family member 4 (STEAP4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STEAP4
• Synonyms: SchLAH; STAMP2; TIARP; TNFAIP9
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_024636, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGAAAACTTGTATAGATGCACTTCCTCTTACTATGAATTCTTCAGAAAAGCAAGAGACTGTATGTA
  TTTTTGGAACTGGTGATTTTGGAAGATCACTGGGATTGAAAATGCTCCAGTGTGGTTATTCTGTTGTTTT
  TGGAAGTCGAAACCCCCAGAAGACCACCCTACTGCCCAGTGGTGCAGAAGTCTTGAGCTATTCAGAAGCA
  GCCAAGAAGTCTGGCATCATAATCATAGCAATCCACAGAGAGCATTATGATTTTCTCACAGAATTAACTG
  AGGTTCTCAATGGAAAAATATTGGTAGACATCAGCAACAACCTCAAAATCAATCAATATCCAGAATCTAA
  TGCAGAGTACCTTGCTCATTTGGTGCCAGGAGCCCACGTGGTAAAAGCATTTAACACCATCTCAGCCTGG
  GCTCTCCAGTCAGGAGCACTGGATGCAAGTCGGCAGGTGTTTGTGTGTGGAAATGACAGCAAAGCCAAGC
  AAAGAGTGATGGATATTGTTCGTAATCTTGGACTTACTCCAATGGATCAAGGATCACTCATGGCAGCCAA
  AGAAATTGAAAAGTACCCCCTGCAGCTATTTCCAATGTGGAGGTTCCCCTTCTATTTGTCTGCTGTGCTG
  TGTGTCTTCTTGTTTTTCTATTGTGTTATAAGAGACGTAATCTACCCTTATGTTTATGAAAAGAAAGATA
  ATACATTTCGTATGGCTATTTCCATTCCAAATCGTATCTTTCCAATAACAGCACTTACACTGCTTGCTTT
  GGTTTACCTCCCTGGTGTTATTGCTGCCATTCTACAACTGTACCGAGGCACAAAATACCGTCGATTCCCA
  GACTGGCTTGACCACTGGATGCTTTGCCGAAAGCAGCTTGGCTTGGTAGCTCTGGGATTTGCCTTCCTTC
  ATGTCCTCTACACACTTGTGATTCCTATTCGATATTATGTACGATGGAGATTGGGAAACTTAACCGTTAC
  CCAGGCAATACTCAAGAAGGAGAATCCATTTAGCACCTCCTCAGCCTGGCTCAGTGATTCATATGTGGCT
  TTGGGAATACTTGGGTTTTTTCTGTTTGTACTCTTGGGAATCACTTCTTTGCCATCTGTTAGCAATGCAG
  TCAACTGGAGAGAGTTCCGATTTGTCCAGTCCAAACTGGGTTATTTGACCCTGATCTTGTGTACAGCCCA
  CACCCTGGTGTACGGTGGGAAGAGATTCCTCAGCCCTTCAAATCTCAGATGGTATCTTCCTGCAGCCTAC
  GTGTTAGGGCTTATCATTCCTTGCACTGTGCTGGTGATCAAGTTTGTCCTAATCATGCCATGTGTAGACA
  ACACCCTTACAAGGATCCGCCAGGGCTGGGAAAGGAACTCAAAACACTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_024636
• ORF Size: 1380 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_024636.3, NP_078912.2
• RefSeq Size: 4488
• RefSeq ORF: 1380
• Locus ID: 79689
• Domains: F420_oxidored
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). Variants 1 and 2 encode the same isoform.