Probable hydrolase PNKD (PNKD) (NM_022572) Human Untagged Clone

CAT#: SC319134

PNKD (untagged)-Human paroxysmal nonkinesigenic dyskinesia (PNKD), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PNKD
• Synonyms: BRP17; DYT8; FKSG19; FPD1; KIPP1184; MR-1; MR-1S; MR1; PDC; PKND1; PNKD1; TAHCCP2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_022572.3 ATGGCTTGGCAGGGCTGGCCCGCGGCGTGGCAGTGGGTCGCCGGCTGCTGGCTCCTCCTC
  GTCCTTGTCCTCGTCCTACTTGTGAGCCCCCGCGGCTGCCGAGCGCGGCGGGGCCTCCGC
  GGTCTGCTCATGGCGCACAGCCAGCGGCTGCTCTTCCGAATCGGGTACAGCCTGTACACC
  CGCACCTGGCTCGGGTACCTCTTCTACCGACAGCAGCTGCGCAGGGCTCGGAATCGCTAC
  CCTAAAGGCCACTCGAAAACCCAGCCCCGCCTCTTCAATGGAGTGAAGGTGCTTCCCATC
  CCTGTCCTCTCGGACAACTACAGCTACCTCATCATCGACACCCAGGCCCAGCTGGCTGTG
  GCTGTGGACCCTTCAGACCCTCGGGCTGTGCAGGCTTCCATTGAAAAGGAAGGGGTCACC
  TTGGTCGCCATTCTGTGTACTCACAAGCACTGGGACCACAGTGGAGGGAACCGTGACCTC
  AGCCGGCGGCACCGGGACTGTCGGGTGTACGGGAGCCCTCAGGACGGCATCCCCTACCTC
  ACCCATCCCCTGTGTCATCAAGATGTGGTCAGCGTGGGACGGCTTCAGATCCGGGCCCTG
  GCTACACCTGGCCACACACAAGGCCATCTGGTCTACCTACTGGATGGGGAGCCCTACAAG
  GGTCCCTCCTGCCTCTTCTCAGGGGACCTGCTCTTCCTCTCTGGCTGTGGGCGGACCTTT
  GAGGGCAATGCAGAGACCATGCTGAGCTCACTGGACACTGTGCTGGGGCTAGGGGATGAC
  ACCCTTCTGTGGCCTGGTCATGAGTATGCAGAGGAGAACCTGGGCTTTGCAGGTGTGGTG
  GAGCCCGAGAACCTGGCCCGGGAGAGGAAGATGCAGTGGGTGCAGCGGCAGCGGCTGGAG
  CGCAAGGGCACGTGCCCATCTACCCTGGGAGAGGAGCGCTCCTACAACCCGTTCCTGAGA
  ACCCACTGCCTGGCGCTACAGGAGGCTCTGGGGCCGGGGCCGGGCCCCACTGGGGATGAT
  GACTACTCCCGGGCCCAGCTCCTGGAAGAGCTCCGCCGGCTGAAGGATATGCACAAGAGC
  AAGTGATGCCCCCAGCGCCCCCAGCCCAGCCCACTCCCCGCATGGGGAGGCCGCCACCAC
  CAACACCTCATCATCCTTCTCATCGCTAACACCACCACCTCCATCGGCACCCAAGCGGGC
  ATCATCCCCCCACACTGCTCAGGGGAGGGGAGGGATCAGGCGATGAGACTGTGAGGCCAA
  AAGAAGCGGGCCTGTTGGAGGCTGGGAACCCCGCAGCGCGAGGCTGCCTCATCAACGGCA
  AGAGGAAAGGAGGGGTCTCGGGACATCTCCAGACCCTACCAACTGGGAGGGTCCCCTCCT
  CCTTCCCTACTCCTGGGACGGCAGCAAGGACATGGGGGCTGCTGTTAGCTTCTCCGTCAG
  GAGGCCTCATCTCACTGTAGCCCTGGAACCCAGGGTCCATCTTGCCCTTCCCCCATCCAT
  GGTTGGGAAAGAAGCTCAGCCCCTCACAGTGGCCTCAAGTGTGATGCCTTACAAAAGCAC
  CACTCAGATGGGCAGCTGGACTCTGGTGTCCTGAGACTCTGCCCTCTTCCCACAGCCTCC
  CTGCCCCACCCATCCCTGCAAAGCCATTTTTCAGACAGAGCCATTCCTAAGAACACTGAA
  GGGCTGGAATGCTGGCTGGCCACTCTCTGCCTCAGTGGCCTCCCTACAGCCTGGAAGAAG
  GAGGGTCCTGATTGCCAAGGAAACCTCCTCATTGGGCTAAGGAGACACTGGAGTCTGGAG
  TGTGGAGCCCCACAGTCTTGCAGGTCACATGCTCTCCTTGCACATCTGGCCTGGTTGTAC
  CCACTGGCCTCTGCCTCTGCCCTGGGCCAAAAGGGCCCCTCCTTGCCAGGGGAGAGACAG
  CCACGGTCCTCTTTGGCCGATGCTGTATTCTCATTTTGGCCCTTGTTCTTAGGCCCGTCT
  GCCCGCCTTCCTCCATCTAACCTTTCCTGTTTTATCCGCAGCCCTTTTCTTCTTTGAGTT
  AGTAAAGATTTATTCTGTAACCTGACACTCATCTGGCCCTTTGCAGTTTGCCAGCCATAT
  TCCCATGTGATTTCCCACTGGATCCAGGCCCCCATCCGGCTGGCAGGAGGGGGCTCTGAC
  GTGCAGGTTGGAAATCAGAAGTCTGTGAGAGCGCGGGAGTGCATGGCAGCTCTGGGTCCC
  AGACCTGGCCCGACCCCTCTGCTTCACCTCCAGCTCTGCTGCTCCTCTACTCTTGGGTCG
  AGATCCCTTTGGAGCCACAGCGAGGAACCCTGTGGTCCTCAGGCAGGTGTACCTTGAGTC
  AGCCAGGAGCCCTCTTTTCCTGTGTCAAAGCCTGCCCTCGGGCTCTGCTCACCTCTGGTG
  ACCCTCCAAGATGCCCCTGCCCTCAGTTTCCCCTCATGATCTGGCCTCTGCCCCCTTCTC
  TAGCCACAGCCTCTAGTACACTTTAGCAATACCACCAGACTAGTTAGAGTTCCCCACTCA
  CCAAGCAAGACATGCAGTTTCATGCCTCTGTGCCTTCGCTCATGCTGTTTCTTCCGACTG
  GAATGCCTTCCCCTGCTCCTCCTGCCTTGTCTGCCTGGCAAGTTCATCTCTCACGATCCC
  CTCAAAGGCCCCCTCCTCCAGGAAGGCAACCCCTGTGCCCCTCCCCTCCAGGCTACCTCT
  GCACTTTGTCAATGCTTCTCTTGTGGCACTTATCACACTGTATTTTACTTGTTTACATGT
  TTGTCTCCCCTTCTAGACTGTGAATCCTTAAGGGCATGGACTGTATCTTATGCATCTCTG
  TATTTCTGCGCCTAGCACGGTGCCTAGCACACAGTAGGCGCTCAATAAATGTTGAATGAA
  TGAATGATTTAATCAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022572.3 unedited
  GGCGATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGATGGCTTGGCAG
  GGCTGGCCCGCGGCGTGGCAGTGGGTCGCCGGCTGCTGGCTCCTCCTCGTCCTTGTCCTC
  GTCCTACTTGTGAGCCCCCGCGGCTGCCGAGCGCGGCGGGGCCTCCGCGGTCTGCTCATG
  GCGCACAGCCAGCGGCTGCTCTTCCGAATCGGGTACAGCCTGTACACCCGCACCTGGCTC
  GGGTACCTCTTCTACCGACAGCAGCTGCGCAGGGCTCGGAATCGCTACCCTAAAGGCCAC
  TCGAAAACCCAGCCCCGCCTCTTCAATGGAGTGAAGGTGCTTCCCATCCCTGTCCTCTCG
  GACAACTACAGCTACCTCATCATCGACACCCAGGCCCAGCTGGCTGTGGCTGTGGACCCT
  TCAGACCCTCGGGCTGTGCAGGCTTCCATTGAAAAGGAAGGGGTCACCTTGGTCGCCATT
  CTGTGTACTCACAAGCACTGGGACCACAGTGGAGGGAACCGTGACCTCAGCCGGCGGCAC
  CGGGACTGTCGGGTGTACGGGAGCCCTCAGACGGCATCCCCTACCTCACCCATCCCCTGT
  GTCATCAAGATGTGGTCAGCGTGGGACGGCTTCAGATCCGGGCCCTGGCTACACCTGGCC
  ACACACAAGGCCATCTGGTCTACCTACTGGATGGGGAGCCCTACAAGGTCCCTCCTGCCT
  CTTCTCAGGGACCTGCTCTTCCTCTCTGGCTGGTGGGCGGACCTTTGAGGGCAATGCAGA
  GACCATGCTGAGCCTCACTGGACAACTGTGCTGGGGCTAGGGGGATGACACCCTTTCTTG
  TTGGCCCTGGTCATGAGTATGCATAGGAGAACCTGGGCTTGCAGTGTGGGTGGAGCCGGA
  ACCTGGCCGGCAAGAATATGCATTGGGTGCACCGCCTCGCGTGGATGGCAAAGGCAACGT
  GCCAA
• Restriction Sites: Please inquire
• ACCN: NM_022572
• ORF Size: 1086 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_022572.3, NP_072094.1
• RefSeq Size: 2986
• RefSeq ORF: 1086
• Locus ID: 25953
• Domains: lactamase_B
• Protein Families: Transmembrane
• Gene Summary: This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2), alternately referred to as the medium form (MR-1M), differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.