PNPO (NM_018129) Human Untagged Clone

CAT#: SC320715

PNPO (untagged)-Human pyridoxamine 5'-phosphate oxidase (PNPO)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PNPO
• Synonyms: HEL-S-302; PDXPO
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_018129.2 GTGCCGGGCCACAGCCGGGTCACGTGGCCGGCGGCCCCCCATGACGTGCTGGCTGCGGGG
  CGTCACGGCGACGTTCGGGCGACCTGCCGAGTGGCCAGGCTACCTCAGTCACCTGTGTGG
  TCGCAGTGCTGCCATGGACCTGGGACCCATGCGCAAGAGTTACCGCGGGGACCGAGAGGC
  ATTTGAGGAGACTCATCTGACCTCTCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGA
  GGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCAC
  CAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTT
  CCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGC
  TTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAA
  GAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGAT
  TGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAA
  AAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAGCCAAAATCCTGGGG
  TGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCA
  TGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGAC
  CCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCT
  GGCCCAGAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCC
  TTCTTTCTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCT
  AATCCTCTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAAT
  GGTGGCGTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTA
  TGATTGATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGAC
  AGACAGGGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTC
  CTAGCATATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATAATTTGAAATT
  TGAACTGGAGAGATCCAGAACCTTGGGAGTCATTAAAGCCAAGTCATTCATAGCAGCCAG
  GAAACAATAGGAACCAAAAGCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTT
  CCCTGGATCCCTCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCCCTGCCTTAAAACACC
  CCACTATCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTTTTTTTACTTAATCTAGCTAGA
  ATCTATTTCTGTTGATTACAACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCT
  TTTTTTCTTTTTTCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGC
  TGGAGTGCAGTGGTGTGATCTTGGCTCACTGAAACCTCTGCCTCCCAGGTTCAAGCAATT
  CTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACACGCCACCACGCCCAACTAA
  TTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATTGTCTCCATCTCT
  TGACCTTGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCAC
  CACACCCAGCGAGACGGGGTTTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTA
  AAGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCACGC
  TTGGCCGGGATAGTATATTTTTATAGCACTTCCCCTACTGATTGCTGCCTTCTCTGTGGC
  TACAAGGGACCCACAGAATTACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTG
  GGAGAGATTTCAAACAATCACACCTGCCTGAGAAGGAGTGGGCTGTCACTAGGAATTTTT
  ATTCCCAGTCCGTCAGGAATTTTGTAGAAGGGCTTCATGTGCTGGTACCAATAGGACAGG
  AAGATTTTAATCAGCTTTACTATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACAT
  ACATTTTCCAAAAAGAAAAATTAAATGATTATAGAGATTAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018129.2 unedited
  GCCATTGTATACGACTCCTATAGGGCGGCCGGGAAATTCGGCACGAGGGTGCCGGGCCAC
  AGCCGGGTCACGTGGCCGGCGGCCCCCCATGACGTGCTGGCTGCGGGGCGTCACGGCGAC
  GTTCGGGCGACCTGCCGAGTGGCCAGGCTACCTCAGTCACCTGTGTGGTCGCAGTGCTGC
  CATGGACCTGGGACCCATGCGCAAGAGTTACCGCGGGGACCGAGAGGCATTTGAGGAGAC
  TCATCTGACCTCTCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCA
  GTGTCCTGACATAGGGGAAGCCAATGCTATGTGTCTGGCTACCTGCACCAGAGATGGAAA
  ACCCTCTGCTCGCATGTTGCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCAC
  TAACTTCGAGAGTCGAAAAGGAAAAGAGCTGGACTCTAATCCCTTTGCTTCCCTTGTCTT
  CTACTGGGAGCCACTTAACCGTCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGA
  GGAGGAGGCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGGCTGTGG
  TCAGCCCACCAGAGTTCTGTGATCCCTGATCGGGAGTATCTGAGAAAGAAAAATGAGGAA
  CTGAAACAGCTCTACCAGGATCAGAGGTGCCCAAGCCAAAATCCTGGGGTGGCCTATGTC
  CTGTACCCCTCAGGTGATGGAGTTCTGGCAAAGGTCAAACCAAACCGCTGCATGACCGGA
  TAAGTCTTTCGGCGGGGCCTACCCACAGGAAAATTTCCCTTTGAGGCCATGACCCACGCG
  GGGGCAGCAAGACTGGGCTCATGAGAGAACTGGAACCTTAAACTCTGGTACTTGCTTGCC
  AATTGGGACTAGGGCCTAGTGTCAAGAGGGTTGGCATTGGACCAGGGCCGTTTTCAACTC
  ACCCATTTCTTTCTCACCTCC
• Restriction Sites: Please inquire
• ACCN: NM_018129
• ORF Size: 786 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018129.2, NP_060599.1
• RefSeq Size: 3437
• RefSeq ORF: 786
• Locus ID: 55163
• Domains: Pyridox_oxidase
• Protein Pathways: Metabolic pathways, Vitamin B6 metabolism
• Gene Summary: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008]