HNRPAB (HNRNPAB) (NM_004499) Human Untagged Clone

CAT#: SC320740

HNRNPAB (untagged)-Human heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HNRNPAB
• Synonyms: ABBP1; HNRPAB
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004499.3 GGCACCGCGCGGGACGGAGCTTGGCTGTTGGTCGGTGGGTTCCCGTGCGGCGGCGGCCAA
  GGAGGAGGAGACACAGTTGGAGCAGCTCCGTGGGCTGACTGGGGCGAGGCCTCAGCAGCG
  CGAGCTTGAGTGCGGCCGAGCCTGCGGCGCCTTCCCCTGCGGGTGGGGACGAGCGGGCCC
  CGCGGCGTCATCGGCGGCGAGGAGCCGCCGCGCCTCGGCCTAGCATGTCGGAAGCGGGCG
  AGGAGCAGCCCATGGAGACGACGGGCGCCACCGAGAACGGACATGAGGCCGTCCCCGAAG
  GCGAGTCGCCGGCCGGGGCTGGCACGGGCGCCGCGGCGGGGGCTGGAGGCGCGACCGCGG
  CGCCCCCGAGCGGGAATCAGAACGGCGCCGAGGGCGACCAGATCAACGCCAGCAAGAACG
  AGGAGGACGCGGGAAAAATGTTCGTTGGTGGCCTGAGCTGGGATACTAGCAAAAAAGATT
  TAAAAGACTATTTTACTAAATTTGGAGAGGTCGTTGACTGTACAATAAAAATGGATCCCA
  ACACTGGACGGTCAAGAGGGTTTGGGTTTATCCTGTTCAAAGATGCAGCCAGTGTGGAGA
  AGGTCCTAGACCAGAAGGAGCACAGGCTGGATGGCCGTGTCATTGACCCTAAAAAGGCCA
  TGGCTATGAAGAAGGACCCGGTGAAGAAAATCTTCGTTGGGGGTCTGAATCCTGAAGCCA
  CTGAGGAAAAGATCAGGGAGTACTTTGGCGAGTTTGGGGAGATTGAGGCCATTGAATTGC
  CAATGGATCCAAAGTTGAACAAAAGACGAGGTTTTGTGTTTATCACCTTTAAAGAAGAAG
  AACCCGTGAAGAAGGTTCTGGAGAAAAAGTTCCATACTGTCAGTGGAAGCAAGTGTGAGA
  TCAAGGTGGCCCAGCCCAAAGAAGTCTATCAGCAGCAGCAGTATGGCTCTGGGGGCCGTG
  GAAACCGCAACCGAGGGAACCGAGGCAGCGGAGGTGGTGGTGGAGGTGGAGGTCAGGGTA
  GTACAAACTACGGCAAGAGCCAGCGACGTGGTGGCCATCAGAATAACTACAAGCCATACT
  GAGGCGGCAGCAGGAGCGACCAACTGATCGCACACATGCTTTGTTTGGATATGGAGTGAA
  CACAATTATGTACCAAATTTAACTTGGCAAACTTTCTATTGCCTGTCCCATGTGCATCTT
  ATTTAAAATTTCCCCCATGGAAATCACTCTCCTGTTGACTATTTCCAGAGCTCTAGGTGT
  TTAGGCAGCGTGTGGTGTCTGAGAGGCCATAGCGCCATCATGGGCTGATTTTTATTACCA
  GGTCCCCCAGAAGCAGGTGGGAGGCTCTGCTTCCTGCTGCCGCTCTGCAGCCTGGACCTG
  TGGACCCTGGTTGTAAAGAGTAAATTGTATCTTAGGAAACCAGTGTCACCTTTTTTTCAC
  CTTTTAATTTTATATTATTTGCGTCATACATTTCCTGTAACGGAAGTGTTAATTTTACTG
  TACTTTTTGGTACCTTTTGGGAATCTAATGTATTGTAAGGTATTTTACACGTGTCCTGAT
  TTTGCCACAACCTGGATATTGAAGCTATCCAAGCTTTTGAAATAAAATTTAAAAACCCCC
  AAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_004499
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004499.3, NP_004490.2
• RefSeq Size: 1696 bp
• RefSeq ORF: 858 bp
• Locus ID: 3182
• Cytogenetics: 5q35.3
• Domains: RRM
• Gene Summary: 'This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region compared to variant 1. The resulting protein (isoform b) is shorter, compared to isoform a.