BHMT2 (NM_017614) Human Untagged Clone

CAT#: SC321102

BHMT2 (untagged)-Human betaine--homocysteine S-methyltransferase 2 (BHMT2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BHMT2
• Synonyms: FLJ20001
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017614.3 AGAGCCGCGGCACCATGGCACCTGCTGGACGCCCGGGGGCCAAGAAGGGGATTTTGGAGC
  GCCTGGAGAGTGGGGAGGTTGTGATTGGAGATGGCAGCTTTCTCATTACTCTGGAGAAGA
  GAGGCTATGTGAAGGCTGGGCTCTGGACTCCAGAGGCAGTGATAGAACACCCAGACGCAG
  TTCGTCAACTTCACATGGAATTCTTGAGAGCAGGATCAAATGTCATGCAGACTTTTACCT
  TTTCTGCCAGTGAGGACAATATGGAAAGCAAGTGGGAAGATGTAAATGCTGCTGCCTGTG
  ACCTCGCCAGGGAAGTGGCTGGCAAAGGTGATGCTTTGGTAGCAGGGGGGATCTGCCAGA
  CATCAATATACAAATACCAGAAGGATGAAGCTAGAATTAAAAAACTTTTTCGACAACAGC
  TAGAAGTTTTTGCCTGGAAAAATGTGGACTTCTTGATTGCAGAGTATTTTGAGCACGTTG
  AAGAAGCTGTGTGGGCTGTGGAAGTCTTAAAAGAATCAGATAGACCCGTGGCAGTTACCA
  TGTGCATAGGCCCAGAGGGAGACATGCATGATATAACCCCCGGAGAATGTGCTGTGAGGC
  TGGTGAAGGCAGGGGCTTCCATCGTTGGCGTGAACTGCCGCTTTGGGCCCGACACCAGCT
  TGAAGACGATGGAGCTCATGAAGGAGGGTCTTGAGTGGGCAGGGCTGAAAGCGCACCTCA
  TGGTGCAGCCTCTGGGGTTCCACGCGCCTGACTGTGGCAAAGAGGGGTTTGTGGATCTCC
  CAGAATATCCCTTTGGACTGGAGTCCAGAGTTGCCACCAGATGGGATATTCAAAAATACG
  CCAGAGAGGCCTACAACCTGGGGGTCAGGTACATTGGCGGGTGCTGTGGATTTGAGCCCT
  ACCACATCAGGGCAATTGCAGAGGAGCTGGCCCCAGAAAGGGGCTTTTTGCCACCAGCTT
  CAGAAAAACACGGCAGCTGGGGAAGTGGTTTGGACATGCACACCAAACCCTGGATTAGAG
  CAAGGGCTCGAAGGGAGTATTGGGAGAATCTGCTGCCAGCTTCAGGCAGACCTTTCTGTC
  CTTCGCTGTCAAAGCCAGACTTCTAAGGAGTAGTGAAAGAAAACCCTGAAATAATCGAAC
  AGGAAAAAGTTGCCCTCAAGCCTGACCTGGAACCGTTCCTCACCTTCATCCTCACCATGC
  CCTGCTATCTCCAGCTGCTGAGCAGCTGAGGTGCTGCAGCCCCTTCCCTTCCAGCCCACA
  AGTGTGTGCATATTGAGCTCCTGCTGTGGTTAAGCACTGCAACAGACTCTACCAGAGATG
  CAAAGAGAAGCGAGAGAGGCACCTTGTTCTCCAAGAACTTACTGTCCAATCATGCTGTGG
  TGCATTCCTTTGAAGATCATGAAGAATAGCCAAACTTGTCTTTGAGGGTGAATTTGACAC
  TTTAAAATAATCAGAAGTCACTGAGACCCAAAGCTAGTGAATAATTCAAGTGACTAAGCT
  AGATACTTGAGGATGATAGAGCAACACTAAACTAAAGCAATGAGTCTGCTTTTTTTAATG
  ATTTATACAATGACTCCAAAGGCAATCCCAAAGAAAAGATGTAAAGAATGTTTTGAGCAA
  TGGTAGCATTATTGAAATAAATGTTTAACTATCCAAAGGAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017614.3 unedited
  TACCATTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGGAGAG
  CCGCGGCACCATGGCACCTGCTGGACGCCCGGGGGCCAAGAAGGGGATTTTGGAGCGCCT
  GGAGAGTGGGGAGGTTGTGATTGGAGATGGCAGCTTTCTCATTACTCTGGAGAAGAGAGG
  CTATGTGAAGGCTGGGCTCTGGACTCCAGAGGCAGTGATAGAACACCCAGACGCAGTTCG
  TCAACTTCACATGGAATTCTTGAGAGCAGGATCAAATGTCATGCAGACTTTTACCTTTTC
  TGCCAGTGAGGACAATATGGAAAGCAAGTGGGAAGATGTAAATGCTGCTGCCTGTGACCT
  CGCCAGGGAAGTGGCTGGCAAAGGTGATGCTTTGGTAGCAGGGGGGATCTGCCAGACATC
  AATATACAAATACCAGAAGGATGAAGCTAGAATTAAAAAACTTTTTCGACAACAGCTAGA
  AGTTTTTGCCTGGAAAAATGTGGACTTCTTGATTGCAGAGTATTTTGAGCACGTTGAAGA
  AGCTGTGTGGGCTGTGGAAGTCTTAAAAGAATCAGATAGACCCGTGGCAGTTACCATGTG
  CATAGGCCCAGAGGGAGACATGCATGATATAACCCCCGGAGAATGTGCTGTGAGGCTGGT
  GAAAGGCAGGGGCTTCCATCGTTGGCGTGAACTGCCGCTTTGGGCCCGACACCAGCTTGA
  AGACGATGGAGCTCATGAACGAGGGTCTTGAGTGGGCAGGCTGAAAGCGCACCTCATGGT
  GCAGCCTCTGGGGTTCACGCGCTGACTGTGGCAAAGAGGGGTTTGGTGGATCTCCAGATA
  TCCCTTTGACTGAGTCCAGAAGTGCCACCAGATGGGATATTCAAAAAATACGCCAGGAAA
  AGCTACAACTGGGGGTCAGGGTACATTTGCC
• Restriction Sites: Please inquire
• ACCN: NM_017614
• ORF Size: 1092 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017614.3, NP_060084.2
• RefSeq Size: 2007
• RefSeq ORF: 1092
• Locus ID: 23743
• Domains: S-methyl_trans
• Gene Summary: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.