INT11 (CPSF3L) (NM_017871) Human Untagged Clone

CAT#: SC321284

CPSF3L (untagged)-Human cleavage and polyadenylation specific factor 3-like (CPSF3L)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CPSF3L
• Synonyms: CPSF3L; CPSF73L; INT11; RC-68; RC68
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017871.4 CCGCAGGCGGGCCTCGCGGGTCCGGGAGCGCGGCGGAGACGATGCCTGAGATCAGAGTCA
  CGCCCTTGGGGGCCGGCCAGGACGTGGGCCGAAGCTGCATCCTGGTCTCCATTGCGGGCA
  AGAATGTCATGCTGGACTGTGGAATGCACATGGGCTTCAATGACGACCGACGCTTCCCTG
  ACTTCTCCTACATCACCCAGAACGGCCGCCTAACAGACTTCCTGGACTGTGTGATCATTA
  GCCACTTCCACCTGGACCACTGCGGGGCACTCCCCTACTTCAGCGAGATGGTGGGCTACG
  ACGGCCCCATCTACATGACTCACCCCACCCAGGCCATCTGCCCCATCTTGCTGGAGGACT
  ACCGCAAGATCGCCGTAGACAAGAAGGGCGAGGCCAACTTCTTCACCTCCCAGATGATCA
  AAGACTGCATGAAGAAGGTGGTGGCTGTCCACCTCCACCAGACGGTCCAGGTAGATGATG
  AGCTGGAGATCAAGGCCTACTATGCAGGCCACGTGCTGGGGGCAGCCATGTTCCAGATTA
  AAGTGGGCTCAGAGTCTGTGGTCTACACGGGTGATTATAACATGACCCCAGACCGACACT
  TAGGAGCTGCCTGGATTGACAAGTGCCGCCCCAACCTGCTCATCACAGAGTCCACGTACG
  CCACGACCATCCGTGACTCCAAGCGCTGCCGGGAGCGAGACTTCCTGAAGAAAGTCCACG
  AGACCGTGGAGCGTGGTGGGAAGGTGCTGATACCTGTGTTCGCGCTGGGCCGCGCCCAGG
  AGCTCTGCATCCTCCTGGAGACCTTCTGGGAGCGCATGAACCTGAAGGTGCCCATCTACT
  TCTCCACGGGGCTGACCGAGAAGGCCAACCACTACTACAAGCTGTTCATCCCCTGGACCA
  ACCAGAAGATCCGCAAGACTTTTGTGCAGAGGAACATGTTTGAGTTCAAGCACATCAAGG
  CCTTCGACCGGGCTTTTGCTGACAACCCAGGACCGATGGTTGTGTTTGCCACGCCAGGAA
  TGCTGCACGCTGGGCAGTCCCTGCAGATCTTCCGGAAATGGGCCGGAAACGAAAAGAACA
  TGGTCATCATGCCCGGCTACTGCGTGCAGGGCACCGTCGGCCACAAGATCCTCAGCGGGC
  AGCGGAAGCTCGAGATGGAGGGGCGGCAGGTGCTGGAGGTCAAGATGCAGGTGGAGTACA
  TGTCATTCAGCGCACACGCGGACGCCAAGGGCATCATGCAGCTGGTGGGCCAGGCAGAGC
  CGGAGAGCGTGCTGCTGGTGCATGGCGAGGCCAAGAAGATGGAGTTCCTGAAGCAGAAGA
  TCGAGCAGGAGCTCCGGGTCAACTGCTACATGCCGGCCAATGGCGAGACGGTGACGCTGC
  CCACAAGCCCCAGCATCCCCGTAGGCATCTCGCTGGGGCTGCTGAAGCGGGAGATGGCGC
  AGGGGCTGCTCCCTGAGGCCAAGAAGCCTCGGCTCCTGCACGGCACCCTGATCATGAAGG
  ACAGCAACTTCCGGCTGGTGTCCTCAGAGCAAGCCCTCAAAGAGCTGGGTCTGGCTGAGC
  ACCAGCTGCGCTTCACCTGCCGCGTGCACCTGCATGACACACGCAAGGAGCAGGAGACGG
  CATTGCGCGTCTACAGCCACCTCAAGAGCGTCCTGAAGGACCACTGTGTGCAGCACCTCC
  CGGACGGCTCTGTGACTGTGGAGTCCGTCCTCCTCCAGGCCGCCGCCCCTTCTGAGGACC
  CAGGCACCAAGGTGCTGCTGGTCTCCTGGACCTACCAGGACGAGGAGCTGGGGAGCTTCC
  TCACATCTCTGCTGAAGAAGGGCCTCCCCCAGGCCCCCAGCTGAGGCCGGCAACTCACCC
  AGCCGCCACCTCTGCCCTCTCCCAGCTGGACAGACCCTGGGCCTGCACTTCAGGACTGTG
  GGTGCCCTGGGTGAACAGACCCTGCAGGTCCCATCCCTGGGGACAGAGGCCTTGTGTCAC
  CTGCCTGCCCAGGCAGCTGTTTGCAGCTGAAGAAACAAACTGGTCTCCAGGCTGTCTTGC
  CTTTATTCCTGGTTAGGGCAGGTGGTCCTAGACAGCAGTTTCCAGTAAAAGCTGAACAAA
  AGACAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017871.4 unedited
  CGACATTGTATACGACTCCTATAGGGCGGCCGGGTAATTCGTCGACTGGATCCGGTACCG
  AGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGACC
  GACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAA
  AACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCA
  CGAGGCCGCAGGCGGGCCTCGCGGGTCCGGGAGCGCGGCGGAGACGATGCCTGAGATCAG
  AGTCACGCCCTTGGGGGCCGGCCAGGACGTGGGCCGAAGCTGCATCCTGGTCTCCATTGC
  GGGCAAGAATGTCATGCTGGACTGTGGAATGCACATGGGCTTCAATGACGACCGACGCTT
  CCCTGACTTCTCCTACATCACCCAGAACGGCCGCCTAACAGACTTCCTGGACTGTGTGAT
  CATTAGCCACTTCCACCTGGACCACTGCGGGGCACTCCCCTACTTCAGCGAGATGGTGGG
  CTACGACGGCCCCATCTACATGACTCACCCCACCCAGGCCATCTGCCCCATCTTGCTGGA
  GGACTACCGCAAGATCGCCGTAGACAAGAAGGGCGAGGCCAACTTCTTCACCTCCCAGAT
  GATCAAAGACTGCATGAAGAAGTGGTGGCTGTCCACCTCCACCAGACGGTCCAGGTAGAT
  GATGAGCTGGAGATCAAGGCCTACTATGCAGGCCACGTGCTGGGGGCAGCCATGTTCCAG
  ATTAAAGTGGGCTCAGAGTCTGTGGTCTACACGGTGATTATAACATGACCCCAGACCGAC
  ACTTAGAGCTGCTGATGACAGTGCCGCCCAACCTGCTCATCACAGAGTCACGTACGCACG
  ACATCGTGACTCAGCGCCTGCCGGGAGCGAGAACTTCTGAGAAGTCCACGAGAACCTGAA
  GCTG
• Restriction Sites: Please inquire
• ACCN: NM_017871
• ORF Size: 1803 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017871.4, NP_060341.2
• RefSeq Size: 2147
• RefSeq ORF: 1803
• Locus ID: 54973
• Gene Summary: The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) lacks two alternate exons in the coding region which results in the use of an upstream start codon, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct N-terminus when it is compared to isoform 1.