AIPL1 (NM_014336) Human Untagged Clone

CAT#: SC321437

AIPL1 (untagged)-Human aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AIPL1
• Synonyms: AIPL2; LCA4
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014336.3 CTGCAGCCATGGATGCCGCTCTGCTCCTGAACGTGGAAGGGGTCAAGAAAACCATTCTGC
  ACGGGGGCACGGGCGAGCTCCCAAACTTCATCACCGGATCCCGAGTGATCTTTCATTTCC
  GCACCATGAAATGTGATGAGGAGCGGACAGTCATTGACGACAGTCGGCAGGTGGGCCAGC
  CCATGCACATCATCATCGGAAACATGTTCAAGCTCGAGGTCTGGGAGATCCTGCTTACCT
  CCATGCGGGTGCACGAGGTGGCCGAGTTCTGGTGCGACACCATCCACACGGGGGTCTACC
  CCATCCTGTCCCGGAGCCTGAGGCAGATGGCCCAGGGCAAGGACCCCACAGAGTGGCACG
  TGCACACGTGCGGGCTGGCCAACATGTTCGCCTACCACACGCTGGGCTACGAGGACCTGG
  ACGAGCTGCAGAAGGAGCCTCAGCCTCTGGTCTTTGTGATCGAGCTGCTGCAGGTTGATG
  CCCCGAGTGATTACCAGAGGGAGACCTGGAACCTGAGCAATCATGAGAAGATGAAGGCGG
  TGCCCGTCCTCCACGGAGAGGGAAATCGGCTCTTCAAGCTGGGCCGCTACGAGGAGGCCT
  CTTCCAAGTACCAGGAGGCCATCATCTGCCTAAGGAACCTGCAGACCAAGGAGAAGCCGT
  GGGAGGTGCAGTGGCTGAAGCTGGAGAAGATGATCAATACTCTGATCCTCAACTACTGCC
  AGTGCCTGCTGAAGAAGGAGGAGTACTATGAGGTGCTGGAGCACACCAGTGATATTCTCC
  GGCACCACCCAGGCATCGTGAAGGCCTACTACGTGCGTGCCCGGGCTCACGCAGAGGTGT
  GGAATGAGGCCGAGGCCAAGGCGGACCTCCAGAAAGTGCTGGAGCTGGAGCCGTCCATGC
  AGAAGGCGGTGCGCAGGGAGCTGAGGCTGCTGGAGAACCGCATGGCGGAGAAGCAGGAGG
  AGGAGCGGCTGCGCTGCCGGAACATGCTGAGCCAGGGTGCCACGCAGCCTCCCGCAGAGC
  CACCCACAGAGCCACCCGCACAGTCATCCACAGAGCCACCTGCAGAGCCACCCACAGCAC
  CATCTGCAGAGCTGTCCGCAGGGCCCCCTGCAGAGCCAGCCACAGAGCCACCCCCGTCCC
  CAGGGCACTCGCTGCAGCACTGAGCCCCCTGAGGCCCACAGCCACCCAGGCAGGGAGCAA
  GTGGCCTGGTCACTTCTGGTTCGATTGACCAGGATCGTGGTGTCACTTTTTAAAATTTAA
  AATTAATTTTTGAAATCAAAGTCAGACACACCCATGGTAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014336.3 unedited
  GGCCTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGA
  GGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGACCG
  ACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAAA
  ACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCAC
  GAGGCTGCAGCCATGGATGCCGCTCTGCTCCTGAACGTGGAAGGGGTCAAGAAAACCATT
  CTGCACGGGGGCACGGGCGAGCTCCCAAACTTCATCACCGGATCCCGAGTGATCTTTCAT
  TTCCGCACCATGAAATGTGATGAGGAGCGGACAGTCATTGACGACAGTCGGCAGGTGGGC
  CAGCCCATGCACATCATCATCGGAAACATGTTCAAGCTCGAGGTCTGGGAGATCCTGCTT
  ACCTCCATGCGGGTGCACGAGGTGGCCGAGTTCTGGTGCGACACCATCCACACGGGGGTC
  TACCCCATCCTGTCCCGGAGCCTGAGGCAGATGGCCCAGGGCAAGGACCCCACAGAGTGG
  CACGTGCACACGTGCGGGCTGGCCAACATGTTCGCCTACCACACGCTGGGCTACGAGGAC
  CTGGACGAGCTGCAGAAGGAGCCTCAGCCTCTGGTCTTTGTGATCGAGCTGCTGCAGGTT
  GATGCCCCGAGTGATTACCAGAGGGAGACCTGGAACCTGAGCAATCATGAGAGATGATGG
  CGGTGCCCGTCCTCCACGGAGAGGGAAATCGGCTTCTTCAGCTGGGCCGCTACGAGGAGG
  CCTCTTCCAGTACCAGAGCCATCATCTGCCTAGACCTGCAGACAGGACAGCGTGGGAGGG
  TGCATGGCTGAAGCTGGAAAGATAGATCAATACTCTGATCCTCACTACTGCCATGGCTGG
  CTTGAAGGGAGGGATC
• Restriction Sites: Please inquire
• ACCN: NM_014336
• ORF Size: 1155 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014336.3, NP_055151.3
• RefSeq Size: 2981
• RefSeq ORF: 1155
• Locus ID: 23746
• Protein Families: Druggable Genome
• Gene Summary: Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (1) encodes the longest isoform (1).