LNX1 (NM_001126328) Human Untagged Clone

CAT#: SC323183

LNX1 (untagged)-Human ligand of numb-protein X 1 (LNX1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LNX1
• Synonyms: LNX; MPDZ; PDZRN2
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001126328, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAACCAGCCAGAGTCTGCCAACGATCCTGAACCCCTGTGTGCAGTGTGTGGCCAAGCCCACTCCTTGG
  AGGAAAACCACTTCTACAGCTATCCAGAGGAAGTGGATGATGACCTCATCTGCCACATCTGCCTGCAGGC
  TTTGCTGGACCCCCTGGACACTCCGTGTGGACACACCTACTGCACCCTCTGCCTCACCAACTTCCTGGTG
  GAGAAGGACTTCTGTCCCATGGACCGCAAGCCTCTGGTTCTGCAGCACTGCAAGAAGTCCAGCATCCTGG
  TCAACAAACTCCTCAACAAGCTACTGGTGACCTGCCCATTCAGGGAGCACTGCACCCAGGTGTTGCAGCG
  CTGTGACCTCGAGCATCACTTTCAAACCAGCTGTAAAGGTGCCTCCCACTACGGCCTGACCAAAGATAGG
  AAGAGGCGCTCACAAGATGGCTGTCCAGACGGCTGTGCGAGCCTCACAGCCACGGCTCCCTCCCCAGAGG
  TTTCTGCAGCTGCCACCATCTCCTTAATGACAGACGAGCCTGGCCTAGACAACCCTGCCTACGTGTCCTC
  GGCAGAGGACGGGCAGCCAGCAATCAGCCCAGTGGACTCTGGCCGGAGCAACCGAACTAGGGCACGGCCC
  TTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAAATCGAGCTTTGAGTGTTCTTCGAAGGA
  CAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCACTGCCCC
  TGAAGTCTTTCCAAGGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTA
  GATCCCAGTGAAAGCCTCTCTATTAGGCTGGTGGGAGGTAGCGAAACCCCACTGGTCCATATCATTATCC
  AACACATTTATCGTGATGGGGTGATCGCCAGAGACGGCCGGCTACTGCCAGGAGACATCATTCTAAAGGT
  CAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGCGGCAGCCCTGCCAGGTG
  CTGTGGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACA
  GACCCCGAGATGACAGCTTTCATGTGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACT
  GGTGCGCAAGGTGGATGAGCCTGGGGTTTTCATCTTCAATGTGCTGGATGGCGGTGTGGCATATCGACAT
  GGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGACATGATCTTCGATATGGCAGCCCAGAAA
  GTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTCGGCAGCG
  GAGCCCTGACATCTTTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGG
  AGCAACACTCCCAAGCCCCTCCATCCTACAATTACTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACC
  CCGGTGAATCTCTCGGCATGACCGTCGCAGGGGGAGCATCACATAGAGAATGGGATTTGCCTATCTATGT
  CATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAGGTGACATTTTGTTGAAT
  GTGGATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCT
  CGATAGTACTCAAAGCTTTGGAAGTCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCT
  GGACTCCAACCACAACATGGCCCCACCCAGTGACTGGTCCCCATCCTGGGTCATGTGGCTGGAATTACCA
  CGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACACAGCTGGAAGTCTGGGCTTCTGCATTG
  TAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAACACCAGC
  ATACAATGATGGAAGAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATG
  ATACATGCTTGCTTGGCAAGACTGCTGAAAGAACTTAAAGGAAGAATTACTCTAACTATTGTTTCTTGGC
  CTGGCACTTTTTTATAG
  
  
• Restriction Sites: Please inquire
• ACCN: NM_001126328
• ORF Size: 2187 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001126328.1, NP_001119800.1
• RefSeq Size: 3199
• RefSeq ORF: 2187
• Locus ID: 84708
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a, also known as LNXp80).