SRC3 (NCOA3) (NM_181659) Human Untagged Clone

CAT#: SC323280

NCOA3 (untagged)-Human nuclear receptor coactivator 3 (NCOA3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NCOA3
• Synonyms: ACTR; AIB-1; AIB1; bHLHe42; CAGH16; CTG26; KAT13B; pCIP; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_181659 edited
  CCGGCGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAA
  TGGCGGCGGGAGGATCAAAATACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAA
  CTGCTTGAACATCCTTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGAT
  TAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATA
  CTCCAGGACAAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAAT
  ATATTGAAGAATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAATG
  TCAAACCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAG
  AGCAAGGAAAAACTATTTCCAATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAG
  GGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGTT
  TCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAAT
  ACCTGCAATATAAGCAAGAGGACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAG
  AAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGGA
  CAAATGAGACCCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACAC
  CACATGATATTCTGGAAGACATAAACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAA
  TGCAGTGCTTTGCCCTGTCTCAGCCACGAGCTATGATGGAGGAAGGGGAAGATTTGCAAT
  CTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGAAAGAACATTTCCATCAAACC
  CTGAGAGCTTTATTACCAGACATGATCTTTCAGGAAAGGTTGTCAATATAGATACAAATT
  CACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATTCAGAGAT
  TTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGCTTATC
  TTAATGGCCATGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGA
  CTGCACAGACAAAAAGCAAACTCTTCCGAAATCCTGTAACAAATGATCGACATGGCTTTG
  TCTCAACCCACTTCCTTCAGAGAGAACAGAATGGATATAGACCAAACCCAAATCCTGTTG
  GACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTCGGTAGGCGGCATGAGTATGT
  CGCCAAACCAAGGCTTACAGATGCCGAGCAGCAGGGCCTATGGCTTGGCAGACCCTAGCA
  CCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCATTGACCC
  CTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGA
  GTAGCCCCCCACATGGGAGTCCTGGTCTTGCCCCAAACCAGCAGAATATCATGATTTCTC
  CTCGTAATCGTGGGAGTCCAAAGATAGCCTCACATCAGTTTTCTCCTGTTGCAGGTGTGC
  ACTCTCCCATGGCATCTTCTGGCAATACTGGGAACCACAGCTTTTCCAGCAGCTCTCTCA
  GTGCCCTGCAAGCCATCAGTGAAGGTGTGGGGACTTCCCTTTTATCTACTCTGTCATCAC
  CAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGTAAAGTAAGCA
  ATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAA
  TGTGTCAGTCAAATAGCAGAGATCACCTCAGTGACAAAGAAAGTAAGGAGAGCAGTGTTG
  AGGGGGCAGAGAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTACTGCAGT
  TACTTACCTGTTCTTCTGATGACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATT
  CAAGTTGTAAAGAATCTTCTGTTAGTGTCACCAGCCCCTCTGGAGTCTCCTCCTCTACAT
  CTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACTGTTACAAGAGAAGCACCGGA
  TTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAGATTACTGCAG
  AAGCCACTGGGAAAGACACCAGCAGTATAACTTCTTGTGGGGACGGAAATGTTGTCAAGC
  AGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTGCTGGACA
  GGGATGATCCTAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATA
  ATAAAATGAGTCAGTGCACCAGCTCCACCATTCCTAGCTCAAGTCAAGAGAAAGACCCTA
  AAATTAAGACAGAGACAAGTGAAGAGGGATCTGGAGACTTGGATAATCTAGATGCTATTC
  TTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCATATCCTCAAATGGTAGTCATC
  TGGGGACTAAGCAACAGGTGTTTCAAGGAACTAATTCTCTGGGTTTGAAAAGTTCACAGT
  CTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTGGATAGCCCTGTTTCTG
  TTGGCTCAAGTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCA
  TGTTGGGTGGGAATCCAAGAATGATGGATAGTCAGGAAAATTATGGCTCAAGTATGGGTG
  GGCCAAACCGAAATGTGACTGTGACTCAGACTCCTTCCTCAGGAGACTGGGGCTTACCAA
  ACTCAAAGGCCGGCAGAATGGAACCTATGAATTCAAACTCCATGGGAAGACCAGGAGGAG
  ATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCTCTATTCCCACATTGCCTCTTC
  GGTCTAATAGCATACCAGGTGCGAGACCAGTATTGCAACAGCAGCAGCAGATGCTTCAAA
  TGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCAT
  CTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCA
  CTCAAAATAGGCCTCTTCTTAGGAATTCCCTGGATGATCTTGTTGGGCCACCTTCCAACC
  TGGAAGGCCAGAGTGACGAAAGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAACA
  CAGATGCCACAGGCCTGGAAGAAATTGACAGAGCTTTGGGCATTCCTGAACTTGTCAATC
  AGGGACAGGCATTAGAGCCCAAACAGGATGCTTTCCAAGGCCAAGAAGCAGCAGTAATGA
  TGGATCAGAAGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCTCCAATGCAAG
  GAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACC
  AGCAAGGCAATTTTCCTCTCCAAGGAATGCACCCACGAGCCAACATCATGAGACCCCGGA
  CAAACACCCCCAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTTT
  TGAATCAGAGCCGACAGGCACTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTG
  CGGTGATGAGGCCTATGATGCAGCCCCAGGTGAGCTCC:::CAGGGTTTTCTTAATGCTC
  AAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCACTTCCGACAACAGAGGGTGG
  CTATGATGATGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGC
  AACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCACCTC
  CTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAG
  CTCCTCCGCAACAGTTTCCATATCAACCAAATTATGGAATGGGACAACAACCAGATCCAG
  CCTTTGGTCGAGTGTCTAGTCCTCCCAATGCAATGATGTCGTCAAGAATGGGTCCCTCCC
  AGAATCCCATGATGCAACACCCGCAGGCTGCATCCATCTATCAGTCCTCAGAAATGAAGG
  GCTGGCCATCAGGAAATTTGGCCAGGAACAGCTCCTTTTCCCAGCAGCAGTTTGCCCACC
  AGGGGAATCCTGCAGTGTATAGTATGGTGCACATGAATGGCAGCAGTGGTCACATGGGAC
  AGATGAACATGAACCCCATGCCCATGTCTGGCATGCCTATGGGTCCTGATCAGAAATACT
  GCTGACATCTCTGCACCAGGACCTCTTAAGGAAACCACTGTACAAATGACACTGCACTAG
  GATTATTGGGAAGGAATCATTGTTCCAGGCATCCATCTTGGAAGAAAGGACCAGCTTTGA
  GCTCCATCAAGGGTATTTTAAGTGATGTCATTTGAGCAGGACTGGATTTTAAGCCGAAGG
  GCAATATCTACGTGTTTTTCCCCCCTCCTTCTGCTGTGTATCATGGTGTTCAAAACAGAA
  ATGTTTTTTGGCATTCCACCTCCTAGGGATATAATTCTGGAGACATGGAGTGTTACTGAT
  CATAAAACTTTTGTGTCACTTTTTTCTGCCTTGCTAGCCAAAATCTCTTAAATACACGTA
  GGTGGGCCAGAGAACATTGGAAGAATCAAGAGAGATTAGAATATCTGGTTTCTCTAGTTG
  CAGTATTGGACAAAGAGCATAGTCCCAGCCTTCAGGTGTAGTAGTTCTGTGTTGACCCTT
  TGTCCAGTGGAATTGGTGATTCTGAATTGTCCTTTACTAATGGTGTTGAGTTGCTCTGTC
  CCTATTATTTGCCCTAGGCTTTCTCCTAATGAAGGTTTTCATTTGCCATTCATGTCCTGT
  AATACTTCACCTCCAGGAACTGTCATGGATGTCCAAATGGCTTTGCAGAAAGGAAATGAG
  ATGACAGTATTTAATCGCAGCAGTAGCAAACTTTTCACATGCTAATGTGCAGCTGAGTGC
  ACTTTATTTAAAAAGAATGGATAAATGCAATATTCTTGAGGTCTTGAGGGAATAGTGAAA
  CACATTCCTGGTTTTTGCCTACACTTACGTGTTAGACAAGAACTATGATTTTTTTTTTTA
  AAGTACTGGTGTCACCCTTTGCCTATATGGTAGAGCAATAATGCTTTTTAAAAATAAACT
  TCTGAAAACCCAAGGCCAGGTACTGCATTCTGAATCAGAATCTCGCAGTGTTTCTGTGAA
  TAGATTTTTTTGTAAATATGACCTTTAAGATATTGTATTATGTAAAATATGTATATACCT
  TTTTTTGTAGGTCACAACAACTCATTTTTACAGAGTTTGTGAAGCTAAATATTTAACATT
  GTTGATTTCAGTAAGCTGTGTGGTGAGGCTACCAGTGGAAGAGACATCCCTTGACTTTTG
  TGGCCTGGGGGAGGGGTAGTGCTCCACAGCTTTTCCTTCCCCACCCCCCAGCCTTAGATG
  CCTCGCTCTTTTCAATCTCTTAATCTAAATGCTTTTTAAAGAGATTATTTGTTTAGATGT
  AGGCATTTTAATTTTTTAAAAATTCCTCTACCAGAACTAAGCACTTTGTTAATTTGGGGG
  GAAAGAATAGATATGGGGAAATAAACTTAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006534 unedited
  NNTGTTCAAATATTTGTATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGCCGG
  CGGCGGCTGCGGGCTGAGCGGCGAGTTTCCGATTTAAAGCTGAGCTGCGAGGAAAAGGCG
  GCGGGAGGATCAAAATACTTGCTGGATGGTGGACTCAGAGACCAATAAAAATAAACTGCT
  TGAACATCCTTTGACTGGTTAGCCAGTTGCTGATGTATATTCAAGATGAGTGGATTAGGA
  GAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATACTCCA
  GGACAAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATT
  GAAGAATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAATGTCAAA
  CCAGATAAATGTGCGATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAA
  GGAAAAACTATTTCCAATGATGATGATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAG
  GGAGTTATTGATAAAGACTCCTTAGGACCGCTTTTACTTCAGGCATTGGATGGTTTCCTA
  TTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAATGTCACACAATACCTG
  CAATATAAGCAAGAGGACCTGGTTAACACAAGTGNTTACAATATCTTACATGAAGAAGAC
  AGAAAGGATTTTCTTAAGAATTTACCACAATCTACAGTTAATGGACGTTTCTTGGACAAA
  TGAGACCCAAAGACAAAAAGCCATACATTTATTGCCGCATGTTGATGAAAACACCCATGA
  TATTCTTGAAGACATAANACGCAGTCCTGAAAGCGCCAGAGAATGAAAAATGCAGGGCTT
  GCCCTGTCTTAGCCCGACCATGATGGAGAAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006534 unedited
  NGGCCATCCTTGGACCGCGCCGCATTCTANATTTTTTTTTTTTTTTTAAGTTTAATTTCC
  CCATATCTATTCTTTCCCCCCAAATTAACAAAGTGCTTAGTTCTGGTAGAGGAATTTTTA
  AAAAATTAAAATGCCTACATCTAAACAAATAATCTCTTTAAAAAGCATTTAGATTAAGAG
  ATTGAAAAGAGCGAGGCATCTAAGGCTGGGGGGTGGGGAAGGAAAAGCTGTGGAGCACTA
  CCCCTCCCCCAGGCCACAAAAGTCAAGGGATGTCTCTTCCACTGGTAGCCTCACCACACA
  GCTTACTGAAATCAACAATGTTAAATATTTAGCTTCACAAACTCTGTAAAAATGAGTTGT
  TGTGACCTACAAAAAAAGGTATATACATATTTTACATAATACAATATCTTAAAGGTCATA
  TTTACAAAAAAATCTATTCACAGAAACACTGCGAGATTCTGATTCAGAATGCAGTACCTG
  GCCTTGGGTTTTCAGAAGTTTATTTTTAAAAAGCATTATTGCTCTACCATATAGGCAAAG
  GGTGACACCAGTACTTTAAAAAAAAAAATCATAGTTCTTGTCTAACACGTAAGTGTAGGC
  AAAAACCAGGAATGTGTTTCACTATTCCCTCAAGACCTCAAGAATATTGCATTTATCCAT
  TTCTTTTAAATAAAGTGCACTCAGCTGCACATTAGCATGTTGAAAAGTTTGCTACTGCTG
  CCATTAAATACTGTCATCTCATTTCCTTTCTGCAAAGCCCATTTGGACATCCTGGACAGT
  TTCCTGGGAGTTGAAGTATTACAGGACATGAATGGGCCAAGGAAAACCTTCCTTAAGTAG
  AAAACCTAGGGCCAAAAATAAGGGCAGAACCACCTCAACCCTN
  
• Restriction Sites: Please inquire
• ACCN: NM_181659
• ORF Size: 4275 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_181659.1, NP_858045.1
• RefSeq Size: 7935
• RefSeq ORF: 4275
• Locus ID: 8202
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.