HBS1L (NM_006620) Human Untagged Clone

CAT#: SC324322

HBS1L (untagged)-Human HBS1-like (S. cerevisiae) (HBS1L), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HBS1L
• Synonyms: EF-1a; eRF3c; ERFS; HBS1; HSPC276
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006620.2 GCCAAGATGGCGCATAGGGGTTCTCCAGGCTGCAGTTGGCGCCTTATCAGTATCTAAGCG
  GAGTGTTTTGGAAGGAGTTAAGGGGCTGTGGCAAACGCCCTCTCCGCCGTCATGGCCCGG
  CATCGGAATGTTCGAGGCTATAACTACGATGAAGATTTTGAAGATGATGATCTCTACGGC
  CAGTCTGTAGAGGATGATTATTGTATTTCGCCGTCAACAGCTGCTCAGTTTATTTATTCA
  CGGCGTGACAAACCTTCCGTTGAGCCTGTGGAAGAATATGATTATGAAGATCTGAAAGAA
  TCTTCCAATTCTGTTTCAAACCATCAGCTCAGTGGATTTGATCAAGCTCGTCTTTATTCA
  TGCCTTGATCACATGAGAGAGGTACTTGGAGATGCTGTGCCAGATGAAATATTAATTGAA
  GCAGTTCTGAAGAACAAGTTTGATGTGCAGAAGGCTTTGTCAGGGGTTCTGGAACAAGAT
  AGAGTGCAGAGTTTGAAGGACAAGAATGAGGCAACAGTATCTACAGGAAAGATAGCAAAA
  GGAAAACCAGTAGATTCCCAGACATCGCGAAGTGAATCTGAAATTGTGCCAAAAGTTGCT
  AAAATGACTGTATCTGGAAAGAAGCAAACTATGGGATTTGAAGTGCCTGGAGTATCTTCT
  GAAGAAAATGGTCATAGTTTCCACACACCTCAAAAAGGACCGCCCATTGAAGATGCCATT
  GCTTCTTCCGATGTTCTTGAGACTGCTTCTAAATCTGCTAATCCACCCCACACGATTCAA
  GCATCAGAAGAGCAGAGTTCAACCCCAGCACCGGTGAAAAAGTCTGGCAAGCTGAGGCAG
  CAAATAGATGTGAAGGCGGAACTGGAGAAGCGGCAAGGAGGGAAGCAGCTACTCAACTTA
  GTGGTCATTGGTCATGTTGATGCTGGGAAAAGTACTCTGATGGGCCATATGCTTTATCTT
  CTGGGTAATATAAACAAAAGAACTATGCATAAGTATGAACAGGAGTCTAAAAAGGCTGGC
  AAAGCTTCGTTTGCATATGCATGGGTCTTGGATGAAACTGGCGAAGAAAGGGAAAGGGGA
  GTAACCATGGATGTTGGTATGACAAAGTTTGAAACCACAACCAAAGTTATTACATTAATG
  GATGCTCCAGGCCATAAGGACTTCATTCCAAATATGATTACAGGAGCAGCCCAGGCGGAT
  GTAGCTGTTTTAGTTGTAGATGCCAGCAGGGGAGAGTTTGAAGCTGGATTTGAGACTGGA
  GGACAAACACGAGAGCATGGACTCTTGGTCCGTTCTCTGGGAGTGACGCAGCTTGCAGTT
  GCAGTTAATAAAATGGATCAGGTTAATTGGCAACAAGAAAGGTTTCAAGAGATTACTGGA
  AAACTTGGGCACTTTCTTAAGCAAGCAGGTTTTAAGGAGAGTGATGTAGGTTTTATTCCT
  ACAAGTGGTCTCAGTGGTGAAAATCTAATCACAAGATCTCAGTCAAGTGAACTCACAAAA
  TGGTATAAAGGACTATGTTTATTAGAACAAATTGATTCCTTTAAGCCTCCCCAGCGATCT
  ATTGACAAACCTTTTAGATTATGTGTGTCCGATGTTTTCAAAGATCAAGGATCTGGATTT
  TGCATAACTGGTAAAATAGAAGCTGGTTATATCCAAACTGGTGACCGACTACTGGCAATG
  CCTCCTAATGAAACTTGTACCGTGAAAGGAATCACTCTGCATGATGAACCTGTCGACTGG
  GCGGCAGCAGGCGATCATGTTAGTCTTACTTTGGTTGGGATGGATATCATCAAAATCAAT
  GTTGGCTGCATATTTTGTGGCCCCAAAGTACCCATTAAAGCTTGCACTCGTTTCAGAGCC
  CGAATCCTCATCTTTAATATTGAAATTCCTATCACTAAAGGATTTCCTGTGCTGTTACAC
  TACCAAACTGTCAGTGAACCCGCCGTTATTAAACGATTGATTAGTGTCTTAAACAAAAGC
  ACGGGTGAAGTCACAAAGAAAAAGCCTAAGTTTTTGACTAAAGGCCAGAATGCATTGGTA
  GAGCTACAGACACAAAGACCAATAGCTCTTGAGCTATATAAAGACTTTAAAGAGCTGGGG
  AGGTTCATGCTACGTTACGGTGGTTCTACAATAGCTGCTGGTGTTGTCACTGAGATAAAA
  GAATGATGGGTCAGAATTTCTACCACGTTTCTGGATACAGTGAAATAGCTAACCTCTGTT
  TCAAGAATGCAGTTATTAAGTCAAAGGAACAATGTGCAATTGATATGTTTTTAGATGAGA
  GAGAAAAATTAAAGCTAAAATTAGCTGCAAAGAAGTATTAATAATCACCTCTGCAAAAAT
  TCTAAGTTGCCAACTGGCAAAGAAAGTCTAATGTTAAAAACAACTTTGCCTTTGAAACGT
  TAATAAATGGATTTACTTTGCTAAGATTTATGGCAAGTGTCAAAAATAGTATCTGAAGAT
  ACTGAATCATCATGAAATGAACTCTACTTCTGGCCAAAGCACAATGTATTTGCAGTTTTC
  TCTTTTGATTCAATTATACTGCACATGTTTTAAGGAAAAGTAACTTAATTGGGTTTTTCA
  GGCAGTTGATATTTGACCTAAGCTTTTTTTTTTTTTTTTTTTCCAGTTAATGCTAAGAAA
  AGATTTGGGGAAGGTTATAATAAAAGTATTTTGTGGTGACCATAAGAATGTCCCTCCCCA
  AACAAGTAAACTTGTGAAAGTTTAATTTGGAATTAGTGGAAGCTGTTCCTTTGAAAGCCA
  AGATATTATTTAAGTTGTAAAGCCAGCTAATAAAATGCCTTAGTTTGAGCATAATAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006620.2 unedited
  TGCTAGCCTGTAAGCCTCCCGCTGTTTTGACCTCCATAGAAGACACCGGGACCGATCCAG
  CCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCTATG
  ACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTGGTA
  CCGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGCCAAGATGGCGCATAGGG
  GTTCTCCAGGCTGCAGTTGGCGCCTTATCAGTATCTAAGCGGAGTGTTTTGGAAGGAGTT
  AAGGGGCTGTGGCAAACGCCCTCTCCGCCGTCATGGCCCGGCATCGGAATGTTCGAGGCT
  ATAACTACGATGAAGATTTTGAAGATGATGATCTCTACGGCCAGTCTGTAGAGGATGATT
  ATTGTATTTCGCCGTCAACAGCTGCTCAGTTTATTTATTCACGGCGTGACAAACCTTCCG
  TTGAGCCTGTGGAAGAATATGATTATGAAGATCTGAAAGAATCTTCCAATTCTGTTTCAA
  ACCATCAGCTCAGTGGATTTGATCAAGCTCGTCTTTATTCATGCCTTGATCACATGAGAG
  AGGTACTTGGAGATGCTGTGCCAGATGAAATATTAATTGAAGCAGTTCTGAAGAACAAGT
  TTGATGTGCAGAAAGCTTTGTCAGGGGTTCTGGAACAAGATAGAGTGCAGAGTTTGAAGG
  ACAAGAATGAGGCAACAGTATCTACAGGAAAGATAGCAAAGGAAAACCAGTAGATTCCCA
  GACATCGCGAAGTGAATCTGAAATTGTGCCAAAGTTGCTAAAATGACTGTATCTGGAAAG
  AAGCAAACTATGGGATTTGAGTGCCTGAAGTATCTTCTGAAGAAATGTCCATAGTTTCCA
  CACCACCTCAAAGACCGGCATGAAGATGCATGCTCTCCGATGTTCTTGGAAAACTGCCTT
  CTAATTCTTGCTATCAA
• Restriction Sites: Please inquire
• ACCN: NM_006620
• ORF Size: 2055 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006620.2, NP_006611.1
• RefSeq Size: 7163
• RefSeq ORF: 2055
• Locus ID: 10767
• Domains: GTP_EFTU, GTP_EFTU_D3, GTP_EFTU_D2
• Gene Summary: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).