PICK1 (NM_001039584) Human Untagged Clone

CAT#: SC324447

PICK1 (untagged)-Human protein interacting with PRKCA 1 (PICK1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PICK1
• Synonyms: PICK; PRKCABP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001039584.1 GTGGGTTCAGGTACCAGCCTGGCCGGGACCCGGCTGTGGGACCAACGCTTCCGGTGAGCG
  ACAGAGGCAGCTCCCCAGGGCCTGGAGACCCGTGGGGCGGACTCTGGGATCTGAGCCTAT
  CGCCCTGGCCTGGAGCCCCCCTTTGTACCTATTCCCCATTCCCCTACCGAGCTGGGCAGT
  TAGCCAGCCCACTCCAACTCTCGGAACCATGTTTGCAGACTTGGATTATGACATCGAAGA
  GGATAAACTCGGAATCCCGACTGTGCCTGGGAAGGTGACCCTGCAGAAGGATGCTCAGAA
  CCTGATCGGGATCAGCATTGGAGGAGGGGCCCAGTACTGTCCCTGCCTCTATATCGTCCA
  GGTATTTGACAACACCCCAGCAGCCTTGGACGGCACAGTGGCAGCTGGCGATGAGATCAC
  CGGTGTCAATGGCAGGTCAATCAAAGGGAAAACTAAGGTGGAGGTGGCGAAGATGATTCA
  GGAGGTGAAGGGGGAGGTGACCATCCACTACAACAAGCTGCAGGCGGACCCCAAGCAGGG
  CATGTCCCTGGACATTGTGTTGAAGAAAGTCAAGCACCGGCTGGTGGAGAACATGAGTTC
  AGGGACCGCAGATGCTCTGGGCCTGAGCCGGGCCATCCTGTGCAATGATGGGCTTGTCAA
  GAGGCTAGAGGAGCTGGAGCGGACCGCTGAGCTATACAAAGGGATGACGGAACACACCAA
  GAACCTCCTACGGGCCTTTTATGAGCTGTCGCAGACTCACCGGGCCTTTGGGGACGTGTT
  CTCCGTGATCGGGGTGCGGGAGCCCCAGCCAGCTGCGAGCGAGGCTTTTGTGAAGTTCGC
  CGATGCCCACCGCAGCATCGAGAAGTTCGGCATTCGGCTTCTGAAAACCATCAAGCCGAT
  GCTGACGGATCTGAACACGTACCTCAACAAAGCCATCCCGGACACTCGCCTCACCATCAA
  GAAGTACCTGGACGTGAAGTTTGAGTACCTGTCGTACTGCCTGAAGGTGAAGGAGATGGA
  TGACGAGGAATACAGCTGCATTGCCCTAGGCGAGCCCCTTTACCGGGTGAGCACCGGCAA
  CTATGAGTACCGCCTGATCCTGCGCTGCCGCCAGGAGGCGCGCGCCCGCTTCTCCCAGAT
  GCGCAAGGATGTGCTGGAGAAGATGGAGCTGCTGGACCAGAAGCACGTCCAGGACATCGT
  GTTCCAGCTGCAGCGCCTCGTGTCCACCATGTCCAAGTACTACAACGACTGCTACGCAGT
  GCTGCGGGATGCCGACGTCTTCCCCATCGAGGTAGACCTGGCGCACACCACATTGGCCTA
  TGGCCTCAACCAGGAGGAGTTCACAGATGGGGAGGAGGAGGAGGAGGAGGAAGACACGGC
  AGCTGGGGAGCCGTCCAGGGATACACGAGGGGCTGCTGGGCCCTTGGACAAGGGTGGAAG
  CTGGTGTGACTCCTGAGTGCCCCGCGGCTGTGGTGCCGGGGGCAGGGTGCGTGGGAGGAC
  GGAGCCTGGGAGCGGGGCGGGGCCGCCGCGCAAGGGGGCGACGCATAAAGGCCTGCTGGC
  TTGGGGCGCCTGCCTCCCTGCTCCTCTGTCCTCGCACAGCGAACCTGGGCTCCTGCCCAG
  GACAGGCACCAGGGTCATGGCCTGGGACCTGGACACTGGCCCCTCCACCCTCCCTCCCCT
  CCCGGCTCCCCGGCCAGAGGGAGAGCTTGGTCTCTGGACCTGCCTTAGGAAGGAGAGGGA
  GGGCAGGAAGGAAAAGAAAGGACTTGGAGGTGGCAGGAGTCCGAGCCCTGCTCCTTGTGG
  GCGCTCACACTGCCCCCGGAGCCTGCTGGGAGTGGGGCCAGCCGTGGACAGCTGAGGTTG
  GGGTCAATGCCTCCTGGGCACCCTTGCCTCGCCCCAGACCGGCCCGTCCAGTCCCCATCA
  CACCTCGGCGGCCTTTATTTATTCTGTTCCCCCAGCTCGGCCACTTCTCTGAAGGAGGGC
  TGGGTTCTGGGCCTGTATCGAATAAACACAAACCTGGATGGCGCAAAAAAAAAAAAAAAA
  AA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001039584.1 unedited
  CGCTAAAAAATGTGTACACGACTCCTATAGGGCGGCCGGGAAAAAAGCACGAGGGGGGGT
  ACAGGCACCAGCCTGGCCGGGACCCGGCTGTGGGACCAACGCTTCCGGGGAGCGACAGAG
  GCAGCTCCCCAGGGCCTGGAGACCCGAGGGGCGGACTCTGGGATCTGAGCCTATCGCCCT
  GGCCTGGAGCCCCCCTTTGTACCTATTCCCCATTCCCCTACCGAGCTGGGCAGTTAGCCA
  GCCCACTCCAACTCTCGGAACCATGTTTGCAGACTTGGATTATGACATCGAAGAGGATAA
  ACTCGGAATCCCGACTGTGCCTGGGAAGGTGACCCTGCAGAAGGATGCTCATAACCTGAT
  CGGGATCAGCATTGGAGGAGGGGCCCAGTACTGTCCCTGCCTCTATATCGTCCAGGTATT
  TGACAACACCCCAGCAGCCTTGGACGGCATAGTGGCAGCTGGCGATGAGATCACCGGTGT
  CAATGGCAGGTCAATCAAAGGGAAAACTAAGGTGGAGGTGGCGAAGATGATTCAGGAGGT
  GAAGGGGGAGGTGACCATCCACTACACAAGCTGCAGGCGGGACCCCAAGCAGGGCCATGT
  CCCTGGGACATTGTGTTGAATAAAGTCAAGCACCGGCTGGTGGGAAACATTGAGTTCAGG
  AACCGCAGATGCTCTGGGCCTGACCGGGCCATCCTGTGCAATGAAGGGCTTGCCAGTAGG
  CTAAGGAGCTGGAACGAACCCGCTGA
• Restriction Sites: Please inquire
• ACCN: NM_001039584
• ORF Size: 1248 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001039584.1, NP_001034673.1
• RefSeq Size: 2073
• RefSeq ORF: 1248
• Locus ID: 9463
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.