EDC3 (NM_001142443) Human Untagged Clone

CAT#: SC325143

EDC3 (untagged)-Human enhancer of mRNA decapping 3 homolog (S. cerevisiae) (EDC3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EDC3
• Synonyms: hYjeF_N2-15q23; LSM16; MRT50; YJDC; YJEFN2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142443, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTACAGATTGGCTGGGAAGTATTGTGTCCATCAATTGTGGAGATAGCTTGGGTGTCTATCAGGGAA
  GAGTGTCAGCTGTGGATCAGGTCAGCCAGACCATTTCTCTCACCCGGCCTTTCCATAATGGAGTGAAGTG
  TCTTGTTCCAGAAGTCACCTTCAGGGCAGGTGACATTACGGAGTTAAAAATTCTGGAGATACCAGGACCT
  GGAGACAACCAACATTTTGGAGACCTTCATCAAACAGAATTAGGCCCCTCTGGTGCTGGCTGCCAAGTGG
  GCATCAATCAGAATGGCACAGGCAAGTTTGTCAAGAAGCCAGCCTCTTCCAGCAGTGCCCCTCAGAATAT
  CCCTAAGAGGACAGATGTGAAGAGCCAGGATGTTGCCGTTTCCCCGCAGCAGCAACAGTGCTCAAAGAGC
  TATGTCGACAGGCACATGGAATCCTTGAGTCAGTCCAAAAGTTTCCGTCGTCGGCACAACTCCTGGTCAT
  CTAGTAGCAGGCACCCAAATCAGGCAACTCCCAAGAAAAGTGGTTTAAAGAATGGCCAGATGAAGAATAA
  AGATGACGAGTGCTTCGGGGATGATATTGAGGAGATCCCAGACACAGATTTTGATTTTGAAGGGAACCTG
  GCTCTTTTTGACAAGGCAGCTGTGTTTGAGGAGATTGATACCTATGAAAGGAGAAGTGGTACCCGTTCCC
  GGGGCATCCCAAATGAAAGGCCCACTCGGTACCGCCATGATGAGAACATCTTGGAGTCCGAGCCCATTGT
  CTATCGACGGATCATAGTGCCCCACAACGTGAGCAAGGAGTTCTGCACGGACTCTGGCCTGGTTGTCCCA
  AGTATTTCCTATGAGCTGCATAAAAAGCTGTTGTCCGTGGCTGAGAAGCATGGGCTGACCCTTGAGCGGA
  GACTGGAGATGACAGGTGTGTGTGCCAGTCAGATGGCACTGACCCTCCTCGGAGGACCTAACAGGTTGAA
  TCCCAAAAATGTTCACCAGAGGCCTACAGTGGCTCTACTGTGTGGACCTCATGTGAAGGGGGCTCAGGGT
  ATCAGCTGTGGAAGGCACCTAGCCAACCATGATGTCCAGGTCATCCTTTTCCTGCCCAATTTTGTCAAGA
  TGTTGGAATCTATCACCAATGAGCTGTCGCTCTTCAGCAAGACCCAAGGCCAACAAGTGTCTAGCCTCAA
  AGATCTGCCCACTAGCCCTGTGGACCTGGTCATCAACTGCCTGGATTGCCCTGAGAACGTCTTCCTGCGC
  GATCAACCCTGGTACAAGGCAGCTGTGGCCTGGGCCAACCAGAACCGGGCACCAGTACTCAGCATAGACC
  CTCCTGTGCATGAAGTCGAACAGGGCATTGATGCCAAATGGTCACTGGCACTGGGCCTGCCTCTGCCACT
  GGGGGAGCACGCAGGCCGTATCTATTTGTGCGACATTGGCATTCCCCAGCAGGTCTTCCAGGAGGTGGGC
  ATCAACTACCACTCGCCCTTTGGCTGCAAGTTTGTTATCCCACTGCACTCTGCTTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001142443
• ORF Size: 1527 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001142443.1, NP_001135915.1
• RefSeq Size: 4086
• RefSeq ORF: 1527
• Locus ID: 80153
• Protein Pathways: RNA degradation
• Gene Summary: This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1-4 encode the same isoform (1).